Results 221 to 230 of about 50,711 (247)
Some of the next articles are maybe not open access.
2022
Sphingosine-1-phosphate (S1P) is a lipid that binds and activates five distinct receptor subtypes, S1P1, S1P2, S1P3, S1P4, S1P5, widely expressed in different cells, tissues and organs. In the cardiovascular system these receptors have been extensively studied, but no drug acting on them has been approved so far for treating cardiovascular diseases. In
Spampinato, Simona Federica +2 more
openaire +4 more sources
Sphingosine-1-phosphate (S1P) is a lipid that binds and activates five distinct receptor subtypes, S1P1, S1P2, S1P3, S1P4, S1P5, widely expressed in different cells, tissues and organs. In the cardiovascular system these receptors have been extensively studied, but no drug acting on them has been approved so far for treating cardiovascular diseases. In
Spampinato, Simona Federica +2 more
openaire +4 more sources
Sphingosine 1-phosphate receptors modulate intracellular Ca2+ homeostasis
Biochemical and Biophysical Research Communications, 2007Ligation of sphingosine 1-phosphate (S1P) to a set of specific receptors named S1P receptors (S1PRs) regulates important biological processes. Although the ability of S1P to increase cytosolic Ca2+ in various cell types is well known, the role of the individual S1PRs has not been fully characterized.
RAPIZZI, ELENA +5 more
openaire +4 more sources
Vascular sphingosine-1-phosphate S1P1 and S1P3 receptors
Drug News & Perspectives, 2004The sphingolipid sphingosine-1-phosphate (S1P) acts on five subtypes of G-protein- coupled receptors, termed S1P(1) (formerly endothelial differentiation gene-1 [Edg-1]), S1P(2) (Edg-5), S1P(3) (Edg-3), S1P(4) (Edg-6) and S1P(5) (Edg-8), and possibly several other "orphan" receptors, such as GPR3, GPR6 and GPR12.
WAEBER C +2 more
openaire +4 more sources
[Sphingosine-1-phosphate/sphingosine-1-phosphate receptor 1 and T cell migration].
Yao xue xue bao = Acta pharmaceutica Sinica, 2018Lipid second messenger sphingosine-1-phosphate (S1P) can activate sphingosine-1-phosphate receptors (S1PRs) and participate in many biological processes, such as central nervous system homeostasis, cytokine production and T cell migration. S1PR1 is the main S1PR expressed on T cell surface.
Xin-pin, Zhuang, Qing, Zhu
openaire +1 more source
Current treatment and recent progress in gastric cancer
Ca-A Cancer Journal for Clinicians, 2021Smita S Joshi, Brian D Badgwell
exaly
Critical care management of chimeric antigen receptor T‐cell therapy recipients
Ca-A Cancer Journal for Clinicians, 2022Alexander Shimabukuro-Vornhagen +2 more
exaly