Neurotoxic activity of venom from the Australian Eastern mouse spider (Missulena bradleyi) involves modulation of sodium channel gating [PDF]
, 2000 Lachlan D. Rash +3 more
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Dissecting the contributions of membrane affinity and bivalency of the spider venom protein DkTx to its sustained mode of TRPV1 activation. [PDF]
J Biol Chem, 2023 Singh Y +8 more
europepmc +1 more source
Loxosceles deserta spider venom induces the expression of vascular endothelial growth factor (VEGF) in keratinocytes. [PDF]
, 2000 Anjali Desai +2 more
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PnPP-15, a Synthetic Peptide Derived from a Toxin from Phoneutria nigriventer Spider Venom, Alleviates Diabetic Neuropathic Pain and Acts Synergistically with Pregabalin in Mice. [PDF]
Toxins (Basel), 2023 Mariano XM +4 more
europepmc +1 more source
Spider venom-derived peptide JZTX-14 prevents migration and invasion of breast cancer cells via inhibition of sodium channels. [PDF]
Front Pharmacol, 2023 Wu W +10 more
europepmc +1 more source
Venom gland organogenesis in the common house spider
Scientific ReportsAbstractVenom is a remarkable innovation found across the animal kingdom, yet the evolutionary origins of venom systems in various groups, including spiders, remain enigmatic. Here, we investigated the organogenesis of the venom apparatus in the common house spider,Parasteatoda tepidariorum.
Hassan, Afrah +3 more
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BioTD: an online database of biotoxins [PDF]
arXivBiotoxins, mainly produced by venomous animals, plants and microorganisms, exhibit high physiological activity and unique effects such as lowering blood pressure and analgesia. A number of venom-derived drugs are already available on the market, with many more candidates currently undergoing clinical and laboratory studies.
arxiv