Results 171 to 180 of about 5,869 (218)

Pharmacology of spider venom toxins

Toxin Reviews, 2014
Spider venom is an intricate combination of target specific enzymatic and non-enzymatic toxins. In addition, the venom also contains polyamine neurotoxins, ATP, AMP, ADP, guanosine, 2,4,6-trihydroxy purine, γ-aminobutyric acid, glutamic acid, aspartic ...
Subbaiah, G. K., Kempaiah, K., Sannaningaiah, D.   +2 more
exaly   +2 more sources

Spider Venom Peptides

, 2006
Spider venom peptides and protein toxins are recognized as highly potent and specific molecular tools that modulate neurotransmission via interaction with a variety of ion channels, receptors, and transporters in vertebrates and invertebrates.
GRAHAM M. NICHOLSON, Nicholson, GM
openaire   +2 more sources

Some of the next articles are maybe not open access.

Related searches:

Spider Venoms and Spider Toxins

Journal of Toxicology: Toxin Reviews, 1998
AbstractSpider venoms and toxins are useful tools for the study of ion channels and synaptic functions of neurons in vertebrates and invertebrates. The components of spider venom, such as proteins, peptides, polyamines and bioamines, are species-specific. The various functions of these toxins are reviewed in this paper.
Masahisa Ori, Hiroyoshi Ikeda
openaire   +1 more source

Molecular diversity of spider venom

Biochemistry (Moscow), 2009
Spider venom, a factor that has played a decisive role in the evolution of one of the most successful groups of living organisms, is reviewed. Unique molecular diversity of venom components including substances of variable structure (from simple low molecular weight compounds to large multidomain proteins) with different functions is considered ...
A A, Vassilevski, S A, Kozlov, E V, Grishin   +2 more
openaire   +2 more sources

Funnelweb–Spider Venom Antagonist

Medical Journal of Australia, 1980
It was found in a series of experiments on anaesthetized monkeys that rat plasma and rat euglobulin fractions contain a substance which could offer some protection against funnelweb-spider envenomation when administered before envenomation or simultaneously with the funnelweb-spider venom. Further work to isolate, identify, and purify this substance is
R K, Atkinson, G, Brewer, W E, Glover, D, Morgans, T A, Torda   +4 more
openaire   +2 more sources

Venomous Snake and Spider Bites in Pregnancy

Obstetrical & Gynecological Survey, 2021
Importance Venomous snake and spider bites are relatively rare in the Unites States and even more so in the pregnant population. However, the impact of a venomous bite, also known as an envenomation, can be serious in a pregnant patient.
Emily, Chen, Sarah, Dotters-Katz, Jeffrey A, Kuller, Megan, Varvoutis   +3 more
openaire   +2 more sources

Pharmacology and biochemistry of spider venoms

Toxicon, 2002
Spider venoms represent an incredible source of biologically active substances which selectively target a variety of vital physiological functions in both insects and mammals. Many toxins isolated from spider venoms have been invaluable in helping to determine the role and diversity of neuronal ion channels and the process of exocytosis.
Rash, Lachlan D., Hodgson, Wayne C.
openaire   +5 more sources

Spider Venomics: Implications for Drug Discovery

Future Medicinal Chemistry, 2014
Over a period of more than 300 million years, spiders have evolved complex venoms containing an extraordinary array of toxins for prey capture and defense against predators. The major components of most spider venoms are small disulfide-bridged peptides that are highly stable and resistant to proteolytic degradation.
Pineda, Sandy S., Undheim, Eivind A. B., Rupasinghe, Darshani B., Ikonomopoulou, Maria P., King, Glenn F.   +4 more
openaire   +5 more sources

Total Synthesis of the Spider-Venom Peptide Hi1a

Organic Letters, 2021
Hi1a is a venom peptide from the Australian funnel-web spider Hadronyche infensa with a complex tertiary structure. Hi1a has neuroprotective and cardioprotective properties due to its potent inhibition of acid-sensing ion channel 1a (ASIC1a) and is currently being pursued as a novel therapy for acute ischemic events.
Nisharnthi M. Duggan, Natalie J. Saez, Daniel Clayton, Elena Budusan, Emma E. Watson, Isaac J. Tucker, Lachlan D. Rash, Glenn F. King, Richard J. Payne   +8 more
openaire   +5 more sources

Structure and pharmacology of spider venom neurotoxins

Biochimie, 2000
Spider venoms are complex mixtures of neurotoxic peptides, proteins and low molecular mass organic molecules. Their neurotoxic activity is due to the interaction of the venom components with cellular receptors, in particular ion channels. Spider venoms have proven to be a rich source of highly specific peptide ligands for selected subtypes of potassium,
P, Escoubas, S, Diochot, G, Corzo
openaire   +2 more sources