Results 41 to 50 of about 5,876 (263)

Brown Spider (Loxosceles) Venom Toxins as Potential Biotools for the Development of Novel Therapeutics

Toxins, 2019
Brown spider envenomation results in dermonecrosis with gravitational spreading characterized by a marked inflammatory reaction and with lower prevalence of systemic manifestations such as renal failure and hematological disturbances. Several toxins make
Daniele Chaves-Moreira, Fernando Hitomi Matsubara, Zelinda Schemczssen-Graeff, Elidiana De Bona, Vanessa Ribeiro Heidemann, Clara Guerra-Duarte, Luiza Helena Gremski, Carlos Chávez-Olórtegui, Andrea Senff-Ribeiro, Olga Meiri Chaim, Raghuvir Krishnaswamy Arni, Silvio Sanches Veiga   +11 more
doaj   +1 more source

Venomic and pharmacological activity of Acanthoscurria paulensis (Theraphosidae) spider venom

Toxicon, 2012
In the present study we conducted proteomic and pharmacological characterizations of the venom extracted from the Brazilian tarantula Acanthoscurria paulensis, and evaluated the cardiotoxicity of its two main fractions. The molecular masses of the venom components were identified by mass spectrometry (MALDI-TOF-MS) after chromatographic separation ...
Caroline Barbosa Farias Mourão, Fagner Neves Oliveira, Andréa Cruz e Carvalho, Claudia Arenas, Harry Morales Duque, Jacqueline Coimbra Gonçalves, Jéssica K. A. Macêdo, Priscilla Galante, Carlos Schwartz, Márcia Renata Mortari, Maria de Fátima M. Almeida Santos, Elisabeth F. Schwartz   +11 more
openalex   +4 more sources

Transcriptomic Analysis of the Spider Venom Gland Reveals Venom Diversity and Species Consanguinity

Toxins, 2019
Selenocosmia jiafu (S. jiafu) has been recently identified as a new species of spider in China. It lives in the same habitat as various other venomous spiders, including Chilobrachys jingzhao (C. jingzhao), Selenocosmia huwena (S. huwena), and Macrothele
Zhaotun Hu, Bo Chen, Zhen Xiao, Xi Zhou, Zhonghua Liu   +4 more
doaj   +1 more source

Molecular basis of the remarkable species selectivity of an insecticidal sodium channel toxin from the African spider Augacephalus ezendami [PDF]

, 2016
The inexorable decline in the armament of registered chemical insecticides has stimulated research into environmentally-friendly alternatives. Insecticidal spider-venom peptides are promising candidates for bioinsecticide development but it is ...
Bosmans, F, Dziemborowicz, S, Gilchrist, J, Herzig, V, Ikonomopoulou, M, King, GF, Kuhn-Nentwig, L, Moreira, LA, Nicholson, GM, Rezende, FO, Smith, JJ   +10 more
core   +1 more source

Comparisons of Protein and Peptide Complexity in Poneroid and Formicoid Ant Venoms [PDF]

, 2016
© 2016 American Chemical Society. Animal venom peptides are currently being developed as novel drugs and bioinsecticides. Because ants use venoms for defense and predation, venomous ants represent an untapped source of potential bioactive toxins.
Aili, SR, Dejean, A, Escoubas, P, Koh, JMS, Nicholson, GM, Orivel, J, Padula, MP, Touchard, A   +7 more
core   +2 more sources

A roadmap to the enzymes from spider venom: biochemical ecology, molecular diversity, and value for the bioeconomy

Frontiers in Arachnid Science
Spiders are ancient and highly successful predators, which use venom for both predation and defense. Their venoms are complex mixtures of potent biological molecules, emerging as a prolific source of biomolecular innovation in agriculture, biomedicine ...
Josephine Dresler, Josephine Dresler, Ignazio Avella, Ignazio Avella, Maik Damm, Maik Damm, Ludwig Dersch, Ludwig Dersch, Jonas Krämer, Jonas Krämer, Andreas Vilcinskas, Andreas Vilcinskas, Andreas Vilcinskas, Tim Lüddecke, Tim Lüddecke   +14 more
doaj   +1 more source

Chemical and Biological Characteristics of Antimicrobial α-Helical Peptides Found in Solitary Wasp Venoms and Their Interactions with Model Membranes

Toxins, 2019
Solitary wasps use their stinging venoms for paralyzing insect or spider prey and feeding them to their larvae. We have surveyed bioactive substances in solitary wasp venoms, and found antimicrobial peptides together with some other bioactive peptides ...
Marcia Perez dos Santos Cabrera, Marisa Rangel, João Ruggiero Neto, Katsuhiro Konno   +3 more
doaj   +1 more source

Isolation of two insecticidal toxins from venom of the Australian theraphosid spider Coremiocnemis tropix [PDF]

, 2016
© 2016 Elsevier Ltd Sheep flystrike is caused by parasitic flies laying eggs on soiled wool or open wounds, after which the hatched maggots feed on the sheep flesh and often cause large lesions.
Alewood, PF, Bosmans, F, Durek, T, Dziemborowicz, S, Er, SY, Gilchrist, J, Herzig, V, Ikonomopoulou, MP, King, GF, Nicholson, GM, Pineda, SS, Smith, JJ   +11 more
core   +1 more source

Who was the real sabertooth predator: Thylacosmilus or Thylacoleo?

The Anatomical Record, EarlyView.
Abstract Sabertoothed mammalian predators, all now extinct, were almost exclusively feloid carnivorans (Eutheria, Placentalia): here a couple of extinct metatherian predators are considered in comparison with the placental sabertooths. Thylacosmilus (the “marsupial sabertooth”) and Thylacoleo (the “marsupial lion”) were both relatively large (puma ...
Christine M. Janis
wiley   +1 more source

Diversification of a single ancestral gene into a successful toxin superfamily in highly venomous Australian funnel-web spiders [PDF]

, 2014
Background: Spiders have evolved pharmacologically complex venoms that serve to rapidly subdue prey and deter predators. The major toxic factors in most spider venoms are small, disulfide-rich peptides.
Antunes, A, Darling, A, Fry, BG, Kely, L, King, GF, Pineda, SS, Sollod, BL, Sunagar, K, Undheim, EAB, Wilson, D   +9 more
core   +2 more sources