Results 31 to 40 of about 389,245 (269)

The miner and the activist: an Australian parable for our carbon constrained world

Journal of Political Ecology, 2010
This paper reviews the meaning of carbon by applying five broad questions to this controversial substance: what is land; what is property; what is ownership; what is value; and what are property rights?
James Arvanitakis, Spike Boydell
doaj   +1 more source

Decay rate of antiS1/S2 IgG serum levels after 6 months of BNT162b2 vaccination in a cohort of COVID-19-naive and COVID-19-experienced subjects

Human Vaccines & Immunotherapeutics, 2022
Vaccination toward SARS-CoV-2 reduced mortality and ‘boosters’ are being implemented. We offer scientific contribution about IgG production in the COVID-19 experienced population.
Fabio Borgonovo, Carlo Alberto Stangalini, Carmine Tinelli, Chiara Mariani, Davide Mileto, Maria Vittoria Cossu, Laura Abbati, Lara Bilardo, Gloria Gagliardi, Miriam Cutrera, Martina Pellicciotta, Luciana Armiento, Gianfranco Dedivitiis, Amedeo F. Capetti, Giuliano Rizzardini   +14 more
doaj   +1 more source

The Screening of Broadly Neutralizing Antibodies Targeting the SARS-CoV-2 Spike Protein by mRNA Immunization in Mice

Pharmaceutics, 2023
Neutralizing antibodies (nAbs), the popular antiviral drugs used for the treatment of COVID-19, are effective in reducing viral load and hospitalization.
Zhiyin An, Yu Zhang, Xiang Yu, Jia Xia, Yanan Yin, Guoming Li, Jing Lu, Xuemei Fan, Yingjie Xu   +8 more
doaj   +1 more source

Effect of the N501Y Mutation on Ligands Complexed with SARS-CoV-2 RBD: Insights on Potential Drug Candidates for COVID-19

Drugs and Drug Candidates, 2023
Bioactive compounds against SARS-CoV-2 targets could be potential treatments for COVID-19. Inhibitors of the receptor-binding domain (RBD) on the viral spike protein can block its binding to the human angiotensin-converting enzyme type II (ACE2) receptor.
Camila Fonseca Amorim da Silva, Samanta Omae Camalhonte, Michell de Oliveira Almeida, Sheila Cruz Araujo, Miriam Sannomiya, João Henrique Ghilardi Lago, Kathia Maria Honorio   +6 more
doaj   +1 more source

Current and Future Direct-Acting Antivirals Against COVID-19

Frontiers in Microbiology, 2020
The coronavirus disease of 2019 (COVID-19) has caused an unprecedented global crisis. The etiological agent is a new virus called the severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2). As of October, 2020 there have been 45.4 million confirmed
Shiu-Wan Chan
doaj   +1 more source

Introduction of Two Prolines and Removal of the Polybasic Cleavage Site Lead to Higher Efficacy of a Recombinant Spike-Based SARS-CoV-2 Vaccine in the Mouse Model

mBio, 2021
The spike protein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been identified as the prime target for vaccine development. The spike protein mediates both binding to host cells and membrane fusion and is also so far the only known
Fatima Amanat, Shirin Strohmeier, Raveen Rathnasinghe, Michael Schotsaert, Lynda Coughlan, Adolfo García-Sastre, Florian Krammer   +6 more
doaj   +1 more source

Spike Train Decoding Without Spike Sorting [PDF]

Neural Computation, 2008
We propose a novel paradigm for spike train decoding, which avoids entirely spike sorting based on waveform measurements. This paradigm directly uses the spike train collected at recording electrodes from thresholding the bandpassed voltage signal.
openaire   +3 more sources

Rethinking, Returning, Reflecting [PDF]

Alternatif Politika, 2017
After almost four decades of feminist International Relations (IR), I here rethink the journey this has entailed – for myself and others -- and contemplate where it has taken us.
V. Spike Peterson
doaj  

Comparative Analysis and Classification of SARS-CoV-2 Spike Protein Structures in PDB

COVID, 2023
The Spike (S) protein of the SARS-CoV-2 virus that causes the COVID-19 disease is considered the most important target for vaccine, drug and therapeutic research as it attaches and binds to the ACE2 receptor of the host cells and allows the entry of this
Memoona Aslam, M. Saqib Nawaz, Philippe Fournier-Viger, Wenjin Li   +3 more
doaj   +1 more source

To spike, or when to spike?

Current Opinion in Neurobiology, 2014
Recent experimental reports have suggested that cortical networks can operate in regimes were sensory information is encoded by relatively small populations of spikes and their precise relative timing. Combined with the discovery of spike timing dependent plasticity, these findings have sparked growing interest in the capabilities of neurons to encode ...
openaire   +4 more sources