Results 51 to 60 of about 525,422 (309)

Biophysical approaches for studying viral entry

FEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

SARS‐CoV‐2 Omicron variant: Immune escape and vaccine development

MedComm, 2022
New genetic variants of severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) constantly emerge through unmitigated spread of the virus in the ongoing Coronavirus disease 2019 pandemic. Omicron (B.1.1.529), the latest variant of concern (VOC), has
Danyi Ao, Tianxia Lan, Xuemei He, Jian Liu, Li Chen, Daniel T. Baptista‐Hon, Kang Zhang, Xiawei Wei   +7 more
doaj   +1 more source

Ternary Spike: Learning Ternary Spikes for Spiking Neural Networks

Proceedings of the AAAI Conference on Artificial Intelligence
The Spiking Neural Network (SNN), as one of the biologically inspired neural network infrastructures, has drawn increasing attention recently. It adopts binary spike activations to transmit information, thus the multiplications of activations and weights can be substituted by additions, which brings high energy efficiency.
Yufei Guo, Yuanpei Chen, Xiaode Liu, Weihang Peng 0001, Yuhan Zhang 0006, Xuhui Huang, Zhe Ma 0001   +6 more
openaire   +4 more sources

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers

FEBS Letters, EarlyView.
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui, Agnes Banreti, Armelle L. Ernst, Guillaume Leseigneur, Uwe J. Meierhenrich   +4 more
wiley   +1 more source

Checkpoints for Spike-Element-Wise ResNet

, 2021
https://github.com/fangwei123456/Spike-Element-Wise ...
Wei Fang (9080993)
core   +1 more source

ConformationLab studio: local AlphaFold2-based protein structure prediction on macOS using ColabFold

SoftwareX
Recent advances in in silico protein structure prediction, particularly through AlphaFold, have enabled highly accurate modelling of proteins and their interactions.
Spike Murphy Müller
doaj   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

FEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Bayesian multi-modal model comparison: a case study on the generators of the spike and the wave in generalized spike–wave complexes [PDF]

, 2010
We present a novel approach to assess the networks involved in the generation of spontaneous pathological brain activity based on multi-modal imaging data.
Lemieux, L., Vaudano, A.E., Daunizeau, Jean, Lemieux, L, Daunizeau, J., Vaudano, A E, Daunizeau, J, Lemieux, Louis, VAUDANO, Anna Elisabetta   +8 more
core   +1 more source

Athlete and Support Staff Perceptions of Training Modalities for the Development of Surfing-Specific Manoeuvres: A Concept Mapping Approach

Journal of Coaching and Sports Science
This study investigated the perspectives of surfers and support staff on the importance and feasibility of common surfing training modalities. The Concept Systems groupwisdomTM web platform was used to collect and analyse data from 29 participants (18 ...
Rick Dann, Jonathon Headrick, Llion Roberts, Vincent Kelly, Alex Donaldson, Alec McKenzie, Steven Duhig   +6 more
doaj   +1 more source