Results 71 to 80 of about 525,422 (309)

Membrane potential fluctuations determine the precision of spike timing and synchronous activity: a model study [PDF]

open access: yes, 2001
Kretzberg J, Egelhaaf M, Warzecha A-K. Membrane potential fluctuations determine the precision of spike timing and synchronous activity: a model study. Journal of computational neuroscience.
Egelhaaf, Martin ; https://orcid.org/   +2 more
core   +1 more source

Is Greenberg's "Macro-Carib" viable?

open access: yesBoletim do Museu Paraense Emílio Goeldi. Ciências Humanas
In his landmark work Language in the Americas, Greenberg (1987) proposed that Macro-Carib was one of the major low-level stocks of South America, which together with Macro-Panoan and Macro-Ge-Bororo were claimed to comprise the putative Ge-Pano-Carib ...
Spike Gildea, Doris Payne
doaj   +1 more source

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

open access: yesMolecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth   +17 more
wiley   +1 more source

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

open access: yesFEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang   +10 more
wiley   +1 more source

Spike-history dependencies affect decoding performance.

open access: yes, 2018
A: Shuffles of responses to repeated stimulus presentations remove different types of correlations, but preserve average locking to the stimulus (PSTH), and thus stimulus-induced correlations.
Gašper Tkačik (213054)   +4 more
core   +1 more source

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

open access: yesFEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

Existence and Stability of a Spike in the Central Component for a Consumer Chain Model [PDF]

open access: yes, 2015
We study a three-component consumer chain model which is based on Schnakenberg type kinetics. In this model there is one consumer feeding on the producer and a second consumer feeding on the first consumer.
Winter, M   +3 more
core   +1 more source

Delivery of DNA‐encoded vaccines and proteins in mice using cutaneous suction‐mediated transfection

open access: yesFEBS Open Bio, EarlyView.
Cutaneous suction‐mediated transfection in mice for delivery of DNA‐encoded vaccines and proteins. A critical limitation of DNA vaccines and other therapeutics is transfection in vivo to produce the encoded antigens or therapeutic proteins. Cutaneous suction‐based methods have demonstrated effectiveness in many animal models and have been successfully ...
Emran O. Lallow   +12 more
wiley   +1 more source

11.2 V Supply, 0.21% Biphasic Stimuli Charge-Balanced Neurostimulator With Switching Spike Suppression: An Application to Intraspinal Microstimulation for Restoring Motor Function

open access: yesIEEE Access
In this paper, a new high-voltage and high-current compliance integrated electrical neurostimulator with charge balancing stimuli is presented. The proposed stimulator uses a stacked structure to provide the 11.2 V power supply delivering a biphasic ...
Mostafa Katebi   +3 more
doaj   +1 more source

Spiked monopoles [PDF]

open access: yesJournal of High Energy Physics, 2018
Abstract We introduce the spiked monopole, which is a ’t Hooft-Polyakov monopole with two charged scalar Higgs fields, of which one enjoys a quartic self-interaction. The free Higgs field behaves as in a BPS monopole, reducing the inter-monopole repulsion. The other Higgs has a spiked profile similar to a non-BPS monopole.
openaire   +3 more sources

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