Results 71 to 80 of about 881,355 (287)

To which extend is the "neural code" a metric ? [PDF]

open access: yes, 2008
Here is proposed a review of the different choices to structure spike trains, using deterministic metrics. Temporal constraints observed in biological or computational spike trains are first taken into account.
Cessac, Bruno   +3 more
core   +3 more sources

Some theoretical results on neural spike train probability models

open access: yes, 2007
This article contains two main theoretical results on neural spike train models. The first assumes that the spike train is modeled as a counting or point process on the real line where the conditional intensity function is a product of a free firing rate
Chan, Hock Peng, Loh, Wei-Liem
core   +2 more sources

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

Whose was the Fifteenth-century Manor Court?

open access: yesJahrbuch für Wirtschaftsgeschichte
As part of a wider literature challenging the notion that many lords engaged in extensive surplus extraction, a recent study focused on inland Flanders has argued that we need to decouple seigneuries, the institutions which structured lordship on the ...
Gibbs Spike
doaj   +1 more source

Is Greenberg's "Macro-Carib" viable?

open access: yesBoletim do Museu Paraense Emílio Goeldi. Ciências Humanas
In his landmark work Language in the Americas, Greenberg (1987) proposed that Macro-Carib was one of the major low-level stocks of South America, which together with Macro-Panoan and Macro-Ge-Bororo were claimed to comprise the putative Ge-Pano-Carib ...
Spike Gildea, Doris Payne
doaj   +1 more source

Age‐Related Characteristics of SYT1‐Associated Neurodevelopmental Disorder

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives We describe the clinical manifestations and developmental abilities of individuals with SYT1‐associated neurodevelopmental disorder (Baker‐Gordon syndrome) from infancy to adulthood. We further describe the neuroradiological and electrophysiological characteristics of the condition at different ages, and explore the associations ...
Sam G. Norwitz   +3 more
wiley   +1 more source

Variability of grain yield components of some new winter wheat genotypes (Triticum aestivum L.)

open access: yesPlant, Soil and Environment, 2002
Variability of grain yield components of some new winter wheat genotypes (e.g. Lara, Lenta, Kruna, Fiesta, Perla, and one line of AG-45) was examined.
M. Sabo, M. Bede, Ž.u. Hardi
doaj   +1 more source

SARS-CoV-2 requires cholesterol for viral entry and pathological syncytia formation

open access: yeseLife, 2021
Many enveloped viruses induce multinucleated cells (syncytia), reflective of membrane fusion events caused by the same machinery that underlies viral entry.
David W Sanders   +18 more
doaj   +1 more source

A Markovian event-based framework for stochastic spiking neural networks

open access: yes, 2011
In spiking neural networks, the information is conveyed by the spike times, that depend on the intrinsic dynamics of each neuron, the input they receive and on the connections between neurons. In this article we study the Markovian nature of the sequence
A Delorme   +44 more
core   +3 more sources

Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky   +8 more
wiley   +1 more source

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