Selective Budding of SARS-CoV-Like Particles from Glycolipid-Enriched Membrane Lipid Rafts and Host Gene Modulation. [PDF]
Pastey MK, Huang Y, Graham B.
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Cryo-EM structure of locked spike glycoprotein from bat SARS-like coronavirus WIV1, molecular dynamics and biophysics across host range. [PDF]
Liu C +10 more
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The Interaction Between Orientin and the Spike of SARS-CoV-2: An In Silico and Experimental Approach. [PDF]
Pacheco GC +3 more
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Q1020R in the spike proteins of MERS-CoV from Arabian camels confers resistance against soluble human DPP4. [PDF]
Chen N +9 more
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Update and reuse: Structure-guided nanobody evolution against SARS-CoV-2 escape. [PDF]
Bu F +13 more
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Determinants of success and failure of antibody-based strategies against respiratory viruses: insights from RSV and SARS-CoV-2. [PDF]
Guo H +5 more
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Incorporation of Spike and Membrane Glycoproteins into Coronavirus Virions [PDF]
The envelopes of coronaviruses (CoVs) contain primarily three proteins; the two major glycoproteins spike (S) and membrane (M), and envelope (E), a non-glycosylated protein. Unlike other enveloped viruses, CoVs bud and assemble at the endoplasmic reticulum (ER)-Golgi intermediate compartment (ERGIC).
Makoto Ujike, Fumihiro Taguchi
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Spike glycoprotein of coronavirus of animals and sars-Cov-2
Indian Journal of Comparative Microbiology, Immunology and Infectious Diseases, 2022Family Coronaviridae comprises genetically and antigenically diverse (both inter- and intra-genotypic) virus populations that infect vertebrates including man, animals and poultry. The coronaviruses (CoVs) have large projections (peplomers/spikes) of about 20nm on the envelope that forms solar corona-like features on the virion, first identified in ...
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Structural Bioinformatics to Unveil Weaknesses of Coronavirus Spike Glycoprotein Stability
2021Alternative strategies for developing antiviral drugs are needed, as vaccines could not be the final answer against the present SARS CoV-2 outbreak, due to the still existing ambiguities in the immunological response to the virus. Thus, SARS CoV-2 enzymes have been thoroughly investigated to develop their inhibitors as antiviral drugs. We have searched
Bongini P. +4 more
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In this article, we report the atomic-resolution prefusion structure of the spike protein from swine acute diarrhea syndrome coronavirus (SADS-CoV). SADS-CoV is a pathogenic alphacoronavirus that was responsible for a large-scale outbreak of fatal disease in pigs and that was reported to be capable of interspecies transmission.
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