Results 141 to 150 of about 51,283 (222)

COVID-19 Infection: Implications for Perioperative and Critical Care Physicians. [PDF]

, 2020
Healthcare systems worldwide are responding to Coronavirus Disease 2019 (COVID-19), an emerging infectious syndrome caused by the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) virus. Patients with COVID-19 can progress from asymptomatic or
Greenland, John R, London, Martin J, Michelow, Marilyn D, Wang, Linlin   +3 more
core  

Antibody-dependent enhancement of SARS coronavirus infection and its role in the pathogenesis of SARS [PDF]

, 2016
1. Anti-SARS-CoV spike antibodies promote infection of primary human immune cells by SARS-CoV. 2. The antibody-dependent enhancement (ADE) infection pathway grants SARS-CoV an opportunity to infect primary human macrophages, but it does not sustain ...
Bruzzone, R, Cheung, CY, Daëron, M, Dutry, ICA, Jaume, MDA, LEUNG, HL, Li, D, Li, PH, Peiris, JSM, Yip, MS   +9 more
core  

Genome-wide bioinformatics analysis of human protease capacity for proteolytic cleavage of the SARS-CoV-2 spike glycoprotein

Microbiology Spectrum
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) primarily enters the cell by binding the virus’s spike (S) glycoprotein to the angiotensin-converting enzyme 2 receptor on the cell surface, followed by proteolytic cleavage by host proteases ...
Evgenii V. Matveev, Gennady V. Ponomarev, Marat D. Kazanov   +2 more
doaj   +1 more source

SARS-CoV-2 spike protein variant binding affinity to an angiotensin-converting enzyme 2 fusion glycoproteins

PLoS ONE, 2022
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), the causative agent of the Coronavirus disease 2019 (Covid-19) pandemic, continues to evolve and circulate globally.
Alicia M. Matthews, Thomas G. Biel, Uriel Ortega-Rodriguez, Vincent M. Falkowski, Xin Bush, Talia Faison, Hang Xie, Cyrus Agarabi, V. Ashutosh Rao, Tongzhong Ju   +9 more
doaj  

Influence of Mutations on Physicochemical Properties of Spike Proteins from Prototypical SARS-CoV-2 Variants of Concern Detected in Amazonian Countries

Microbiology Research
Since the emergence of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), the viral spike protein (S) has become a target to describe appropriate epitopes for vaccine development and to carry out epidemiological surveillance, especially ...
Adriana Conceição B. Silva, Carlos Alberto M. Carvalho   +1 more
doaj   +1 more source

SARS-CoV-2 spike-reactive naïve B cells and pre-existing memory B cells contribute to antibody responses in unexposed individuals after vaccination

Frontiers in Immunology
IntroductionSince December 2019, the emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causing coronavirus disease 2019 (COVID-19) has presented considerable public health challenges.
Shishan Teng, Shishan Teng, Yabin Hu, Yabin Hu, You Wang, You Wang, Yinggen Tang, Yinggen Tang, Qian Wu, Xingyu Zheng, Xingyu Zheng, Rui Lu, Rui Lu, Dong Pan, Dong Pan, Fen Liu, Fen Liu, Tianyi Xie, Tianyi Xie, Chanfeng Wu, Chanfeng Wu, Yi-Ping Li, Wenpei Liu, Xiaowang Qu   +23 more
doaj   +1 more source

Coronavirus (2019-nCoV) Deactivation via Spike Glycoprotein Shielding by Old Drugs, Bioinformatic Study

, 2020
The disease of COVID-19 comprises the most serious against human health worldwide with a high rate of virulence and mortality. The disease is caused by the 2019-nCoV virus from the beta coronavirus family. The virus makes use of its surface glycoprotein named S protein or spike to enter the human cells.
openaire   +2 more sources

IN-SILICO STUDY OF SILYMARIN AGAINST SPIKE GLYCOPROTEIN OF CORONAVIRUS

International Research Journal of Modernization in Engineering Technology and Science, 2022
openaire   +1 more source

Design and Characterization of an HRC-Derived Peptide Inhibitor of Canine Coronavirus Spike-Mediated Fusion. [PDF]

Pathogens
Iovane V, Giugliano R, Gentile A, Della Marca R, Di Clemente L, Chianese A, Montagnaro S, De Filippis A, Galdiero M, Zannella C.   +9 more
europepmc   +1 more source

Insertion in the N-Terminal Domain of the SARS-CoV-2 Spike Glycoprotein Affects Antibody Recognition and Phenotypic Properties. [PDF]

Viruses
Ermolaeva EA, Zyrina AN, Sirazova DI, Lunin AS, Motov AS, Chernavtseva AD, Gancharova OS, Kozlovskaya LI, Shishova AA, Siniugina AA, Ishmukhametov AA.   +10 more
europepmc   +1 more source