Results 81 to 90 of about 76,288 (243)
A Tale of Two Viruses: The Distinct Spike Glycoproteins of Feline Coronaviruses [PDF]
Viruses, 2020 Feline coronavirus (FCoV) is a complex viral agent that causes a variety of clinical manifestations in cats, commonly known as feline infectious peritonitis (FIP). It is recognized that FCoV can occur in two different serotypes. However, differences in the S protein are much more than serological or antigenic variants, resulting in the effective ...
Javier A. Jaimes +4 more
openaire +5 more sources
Neutralization assay with SARS-CoV-1 and SARS-CoV-2 spike pseudotyped murine leukemia virions
Virology Journal, 2021 Background Virus neutralization by antibodies is an important prognostic factor in many viral diseases. To easily and rapidly measure titers of neutralizing antibodies in serum or plasma, we developed pseudovirion particles composed of the spike ...
Yue Zheng +12 more
doaj +1 more source
Advanced Science, EarlyView.A healthy gut barrier shields underlying fibroblasts from luminal shear forces, illustrating that “good fences make good neighbors.” Barrier damage exposes fibroblasts to shear stress, inducing cell death and the emergence of stress‐adapted, profibrotic fibroblasts. Sustained shear exposure promotes the formation of stiff aggregates of mechanoadapative
Soyoun Min +6 more
wiley +1 more source
Evolutionary aspect of spike glycoprotein's conformational dynamics
Physical Chemistry Chemical PhysicsThe conformational transition of the receptor binding domain (RBD) of the SARS-CoV-2 spike (S) protein from the “closed” to “open” state.
Wentao Xu, Tianyu Guo, Haibin Su
openaire +2 more sources
Molecules, 2020 The worldwide health emergency of the SARS-CoV-2 pandemic and the absence of a specific treatment for this new coronavirus have led to the use of computational strategies (drug repositioning) to search for treatments.
Gema Lizbeth Ramírez-Salinas +3 more
doaj +1 more source
Frontiers in Immunology, 2023 BackgroundUnderstanding the humoral immune response towards viral infection and vaccination is instrumental in developing therapeutic tools to fight and restrict the viral spread of global pandemics. Of particular interest are the specificity and breadth
Peter Lorenz +5 more
doaj +1 more source
Advanced Science, EarlyView.Fibronectin 1 (FN1)‐expressing subicular subpopulations encode novel object preference and selectively govern retrieval of novel object recognition (NOR) via affecting excitability of entorhinal‐projecting circuit through large conductance Ca2+‐activated potassium (BK) channel. ABSTRACT Novel object recognition (NOR), referring to the cognitive ability
Fan Fei +15 more
wiley +1 more source
SARS-CoV-2 spike treatment and transfection impairs airway epithelial repair
ERJ Open ResearchBackground The airway epithelium serves as a physical and immune barrier against inhaled insults. This tissue is susceptible to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and, following injury, the airway epithelium undergoes ...
Tony Guo +5 more
doaj +1 more source
Molecular characterization and detection of infectious bronchitis virus [PDF]
, 2012 This thesis deals with the molecular characterization and detection of infectious bronchitis virus (IBV), an important pathogen that causes heavy losses in the poultry populations worldwide.
Abro, Shahid Hussain
core
, 2023 In our search for a possible Achilles’ heel of SARS-CoV-2, we explored the variability of 1,382,462 complete sequences of the viral spike glycoprotein, all the ones that we could retrieve from the NCBI SARS-CoV-2 databank as of March 6, 2023.
Annalisa Santucci +7 more
core +1 more source