Results 91 to 100 of about 403,301 (348)

Urine Specimens from Pregnant and Nonpregnant Women Inhibitory to Amplification of \u3cem\u3eChlamydia trachomatis\u3c/em\u3e Nucleic Acid by PCR, Ligase Chain Reaction, and Transcription-Mediated Amplification: Identification of Urinary Substances Associated with Inhibition and Removal of Inhibitory Activity [PDF]

, 1998
The presence of endogenous amplification inhibitors in urine may produce false-negative results for the detection of Chlamydia trachomatis nucleic acids by tests such as PCR, ligase chain reaction (LCR), and transcription-mediated amplification (TMA ...
Chernesky, Max A., Chong, Sylvia, Faught, M., Guthrie, Dawn M., Jang, Dan, Luinstra, Kathy, Mahoney, James, Sellors, John W.   +7 more
core   +1 more source

Whole genome sequencing-based mapping and candidate identification of mutations from fixed zebrafish tissue [PDF]

, 2017
As forward genetic screens in zebrafish become more common, the number of mutants that cannot be identified by gross morphology or through transgenic approaches, such as many nervous system defects, has also increased.
Ackerman, Sarah D, Gray, Ryan S, Harty, Breanne L, Herbert, Amy L, Holmgren, Melanie, Johnson, Stephen L, Monk, Kelly R, O\u27Reilly-Pol, Thomas, Sanchez, Nicholas E   +8 more
core   +3 more sources

Molecular Evolutionary Analyses of the Spike Protein Gene and Spike Protein in the SARS-CoV-2 Omicron Subvariants

Microorganisms, 2023
To better understand the evolution of the SARS-CoV-2 Omicron subvariants, we performed molecular evolutionary analyses of the spike (S) protein gene/S protein using advanced bioinformatics technologies. First, time-scaled phylogenetic analysis estimated that a common ancestor of the Wuhan, Alpha, Beta, Delta variants, and Omicron variants/subvariants ...
Norika Nagasawa, Ryusuke Kimura, Mao Akagawa, Tatsuya Shirai, Mitsuru Sada, Kaori Okayama, Yuka Sato-Fujimoto, Makoto Saito, Mayumi Kondo, Kazuhiko Katayama, Akihide Ryo, Makoto Kuroda, Hirokazu Kimura   +12 more
openaire   +3 more sources

Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky, Cara Joyce, H. Jeremy Bockholt, Paul A. Rudnick, William H. Adams, Fiona McAllister, Justin W. Smock, Michael A. Newton, Jane S. Paulsen   +8 more
wiley   +1 more source

Phytochemicals as a potential inhibitor of Spike Protein of SARS-CoV-2 Omicron Variant

Jurnal Kedokteran Diponegoro, 2023
Background: More than 50 mutations have been found in Omicron SARS-CoV-2. Most Omicron mutations are located in the spike protein, which plays a pivotal role in virus infection.
Tuti Ratnasari, Faizah Fulyani, Endang Mahati   +2 more
doaj   +1 more source

COVID‐19 Vaccination is not Associated with the Development of Idiopathic Inflammatory Myositis in U.S. Veterans

Arthritis Care &Research, Accepted Article.
Objective Several case reports have proposed a potential association between COVID‐19 vaccination and the subsequent development of idiopathic inflammatory myositis (IIM). This study examined prior COVID‐19 vaccination in US Veterans who developed new‐onset IIM compared to those without new‐onset IIM.
Caleb Hernández, Naomi Schlesinger, Jorge Rojas, Jessica A. Walsh, Tawnie J Braaten, Gary A Kunkel, Makoto Jones, Brian C Sauer, Julio Facelli, Grant W. Cannon, Dorota Lebiedz‐Odrobina   +10 more
wiley   +1 more source

A Magnetic Bead-Based Sensor for the Quantification of Multiple Prostate Cancer Biomarkers. [PDF]

, 2015
Novel biomarker assays and upgraded analytical tools are urgently needed to accurately discriminate benign prostatic hypertrophy (BPH) from prostate cancer (CaP).
Brooks, James D, Chang, Edwin, Chen, Zuxiong, Gambhir, Sanjiv S, Jokerst, Jesse V, Mitchell, Breeana, Nolley, Rosalie, Xu, Lingyun   +7 more
core   +4 more sources

Retractions in rheumatology: trends, causes, and implications for research integrity

Arthritis Care &Research, Accepted Article.
Objective We aimed to describe the trends and main reasons for study retraction in rheumatology literature. Methods We reviewed the Retraction Watch database to identify retracted articles in rheumatology. We recorded the main study characteristics, authors’ countries, reasons for retraction, time from publication to retraction, and trends over time ...
Anna Maria Vettori, Michele Iudici
wiley   +1 more source

Metabotropic Glutamate Receptor Activation in Cerebelar Purkinje Cells as Substrate for Adaptive Timing of the Classicaly Conditioned Eye Blink Response [PDF]

, 1995
To understand how the cerebellum adaptively times the classically conditioned nictitating membrane response (NMR), a model of the metabotropic glutamate receptor (mGluR) second messenger system in cerebellar Purkinje cells is constructed.
Bullock, Daniel, Fiala, John C., Grossberg, Stephen   +2 more
core   +1 more source

The Future of the COVID-19 Pandemic: How Good (or Bad) Can the SARS-CoV2 Spike Protein Get? [PDF]

, 2022
Matthew A. Nugent
openalex   +1 more source