Results 81 to 90 of about 7,152,333 (341)
A therapeutic neutralizing antibody targeting receptor binding domain of SARS-CoV-2 spike protein
Nature Communications, 2021 Vaccines and therapeutics are urgently needed for the pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Here, we screen human monoclonal antibodies (mAb) targeting the receptor binding domain (RBD) of the viral spike ...
Cheolmin Kim +44 more
semanticscholar +1 more source
Evaluating SARS-CoV-2 Spike Protein Transfection in HEK-293T Cells for VLP Applications
Journal of Experimental Life ScienceThe spike protein in SARS-CoV-2 works mainly to initiate infections, especially for binding to host cells and fusing with cell membranes. Characterizing SARS-CoV-2 spikes protein transfection cells could optimize the production of VLP in HEK-293T cells ...
Ilmiana Nurur Rohmah +6 more
doaj +1 more source
Integrative structural studies of the SARS-CoV-2 spike protein during the fusion process (2022)
Current Research in Structural Biology, 2022 SARS-CoV-2 is the virus responsible for the COVID-19 pandemic and catastrophic, worldwide health and economic impacts. The spike protein on the viral surface is responsible for viral entry into the host cell. The binding of spike protein to the host cell
Jacob C. Miner +5 more
doaj +1 more source
The Possible Role of TASK Channels in Rank-Ordered Recruitment of Motoneurons in the Dorsolateral Part of the Trigeminal Motor Nucleus. [PDF]
, 2016 Because a rank-ordered recruitment of motor units occurs during isometric contraction of jaw-closing muscles, jaw-closing motoneurons (MNs) may be recruited in a manner dependent on their soma sizes or input resistances (IRs). In the dorsolateral part of
Emura, Norihito +18 more
core +2 more sources
COVID-19 and chronological aging : senolytics and other anti-aging drugs for the treatment or prevention of corona virus infection? [PDF]
, 2020 COVID-19, also known as SARS-CoV-2, is a new emerging zoonotic corona virus of the SARS (Severe Acute Respiratory Syndrome) and the MERS (Middle East Respiratory Syndrome) family.
Auwerx +30 more
core +2 more sources
medRxiv, 2021 We identified a novel SARS-CoV-2 variant by viral whole-genome sequencing of 2,172 remnant nasal/nasopharyngeal swab samples from 44 counties in California. Named B.1.427/B.1.429 or 20C/L452R, the variant emerged around May 2020 and increased from 0% to >
Xianding Deng +45 more
semanticscholar +1 more source
Human coronavirus spike protein-host receptor recognition
Progress in Biophysics and Molecular Biology, 2021 A variety of coronaviruses (CoVs) have infected humans and caused mild to severe respiratory diseases that could result in mortality. The human CoVs (HCoVs) belong to the genera of α- and β-CoVs that originate in rodents and bats and are transmitted to humans via zoonotic contacts.
openaire +2 more sources
The Comparison of SARS-CoV-2, SARS-CoV, and MERS-CoV Genome and Spike Protein Variations
Jurnal Riset Biologi dan Aplikasinya, 2021 SARS-CoV-2 is a virus that has caused COVID-19 pandemic. This virus is a new variant of the SARS-CoV virus and also closely related to MERS-CoV, which caused similar acute respiratory infections. All these viruses recognize target cells by binding to the
Choirun Nita Fikriani +2 more
doaj +1 more source
, 2017 Monitoring the kinetics and conformational dynamics of single enzymes is crucial in order to better understand their biological functions as these motions and structural dynamics are usually unsynchronized among the molecules.
Baaske, Martin D. +4 more
core +1 more source
Revealing networks from dynamics: an introduction [PDF]
, 2014 What can we learn from the collective dynamics of a complex network about its interaction topology? Taking the perspective from nonlinear dynamics, we briefly review recent progress on how to infer structural connectivity (direct interactions) from ...
Casadiego, Jose, Timme, Marc
core +1 more source