Results 61 to 70 of about 3,974,865 (310)
VaccinesThe emergence of new SARS-CoV-2 variants continues to cause challenging problems for the effective control of COVID-19. In this study, we tested the hypothesis of whether a strategy of multivalent and sequential heterologous spike protein vaccinations ...
Rong Liu +10 more
doaj +1 more source
, 2021 Flowchart of patient receiving BNT162b2-mRNA vaccines and analysed for IgG anti-SARS-CoV-2 Spike-Protein-RBD.
Jean-Philippe Bourdenx (11524599) +6 more
core +1 more source
Coronavirus Spike Protein and Tropism Changes
, 2016 (Uploaded by Plazi for the Bat Literature Project) Coronaviruses (CoVs) have a remarkable potential to change tropism. This is particularly illustrated over the last 15 years by the emergence of two zoonotic CoVs, the severe acute respiratory syndrome (SARS)- and Middle East respiratory syndrome (MERS)-CoV. Due to their inherent genetic variability, it
Hulswit, R J G +2 more
openaire +4 more sources
Strategies for the Management of Spike Protein-Related Pathology
Microorganisms, 2023 In the wake of the COVID-19 crisis, a need has arisen to prevent and treat two related conditions, COVID-19 vaccine injury and long COVID-19, both of which can trace at least part of their aetiology to the spike protein, which can cause harm through several mechanisms.
Matthew T.J. Halma +3 more
openaire +3 more sources
Evaluating SARS-CoV-2 Spike Protein Transfection in HEK-293T Cells for VLP Applications
Journal of Experimental Life ScienceThe spike protein in SARS-CoV-2 works mainly to initiate infections, especially for binding to host cells and fusing with cell membranes. Characterizing SARS-CoV-2 spikes protein transfection cells could optimize the production of VLP in HEK-293T cells ...
Ilmiana Nurur Rohmah +6 more
doaj +1 more source
The SARS-CoV-2 spike protein is vulnerable to moderate electric fields
Nature Communications, 2021 The SARS-CoV-2 Spike protein is essential for viral infectivity and binds to the host receptor ACE2. Here, the authors present MD simulations of the Spike protein and its variants of concern and observe that the Spike protein is destabilised by moderate ...
Claudia R. Arbeitman +3 more
doaj +1 more source
Predicted 3D Models of the SARS-CoV-2 Spike Protein Membrane Proximal External Region and Transmembrane Domain [PDF]
, 2020 The transmembrane helix domain (TMD), membrane proximal external region (MPER) and part of heptad repeat 2 (HR2) domain in SARS-CoV-2 spike protein were modelled using a constrained fold-and-dock strategy.
Alexander, Izvorski
core +1 more source
Relative Mutant N501Y SARS-CoV-2 Spike Protein RBD Inhibition of Anti-Spike Protein IgG and ACE-2 Binding to Spike Protein Species [PDF]
, 2021 ABSTRACT In the SARS-CoV-2 coronavirus pandemic of 2019 (COVID-19), it has become evident that the ACE-2 receptor-binding domain (RBD) of the viral spike protein (SP) is the target of neutralizing antibodies that comprise a critical element of protective immunity to the virus.
Melvin E. Klegerman +2 more
openaire +1 more source
The Comparison of SARS-CoV-2, SARS-CoV, and MERS-CoV Genome and Spike Protein Variations
Jurnal Riset Biologi dan Aplikasinya, 2021 SARS-CoV-2 is a virus that has caused COVID-19 pandemic. This virus is a new variant of the SARS-CoV virus and also closely related to MERS-CoV, which caused similar acute respiratory infections. All these viruses recognize target cells by binding to the
Choirun Nita Fikriani +2 more
doaj +1 more source
Corrigendum: Evaluating SARS-CoV-2 Spike Protein Transfection in HEK-293T Cells for VLP Applications
Journal of Experimental Life ScienceThe spike protein of SARS-CoV-2 is crucial for initiating infections by binding to host cells and mediating membrane fusion. In this study, HEK-293T cells were transfected with plasmids encoding three structural proteins of SARS-CoV-2, i.e., Spike ...
Ilmiana Nurur Rohmah +7 more
doaj +1 more source