Results 71 to 80 of about 7,152,333 (341)
Heliyon, 2021 Coronavirus disease 2019 (COVID-19), an infectious disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has now spread globally. Some patients develop severe complications including multiple organ failure. It has been suggested
K. Shirato, T. Kizaki
semanticscholar +1 more source
Adaptive Evolution of the Spike Protein in Coronaviruses
Molecular Biology and Evolution, 2023 Abstract Coronaviruses are single-stranded, positive-sense RNA viruses that can infect many mammal and avian species. The Spike (S) protein of coronaviruses binds to a receptor on the host cell surface to promote viral entry. The interactions between the S proteins of coronaviruses and receptors of host cells are extraordinarily complex,
Xiaolu Tang +3 more
openaire +2 more sources
Modeling the architecture of depolymerase-containing receptor binding proteins in Klebsiella phages [PDF]
, 2019 Klebsiella pneumoniae carries a thick polysaccharide capsule. This highly variable chemical structure plays an important role in its virulence. Many Klebsiella bacteriophages recognize this capsule with a receptor binding protein (RBP) that contains a ...
Briers, Yves +3 more
core +2 more sources
Coronavirus Spike Protein and Tropism Changes
, 2016 (Uploaded by Plazi for the Bat Literature Project) Coronaviruses (CoVs) have a remarkable potential to change tropism. This is particularly illustrated over the last 15 years by the emergence of two zoonotic CoVs, the severe acute respiratory syndrome (SARS)- and Middle East respiratory syndrome (MERS)-CoV. Due to their inherent genetic variability, it
Hulswit, R J G +2 more
openaire +3 more sources
VaccinesThe emergence of new SARS-CoV-2 variants continues to cause challenging problems for the effective control of COVID-19. In this study, we tested the hypothesis of whether a strategy of multivalent and sequential heterologous spike protein vaccinations ...
Rong Liu +10 more
doaj +1 more source
Genome Composition and Divergence of the Novel Coronavirus (2019-nCoV) Originating in China. [PDF]
, 2020 An in-depth annotation of the newly discovered coronavirus (2019-nCoV) genome has revealed differences between 2019-nCoV and severe acute respiratory syndrome (SARS) or SARS-like coronaviruses.
Cheng, Genhong +15 more
core
Molecular aspects of MERS-CoV [PDF]
, 2017 This article is made available for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source.
Al-Ahmed, Shamsah H. +3 more
core +1 more source
Structural impact on SARS-CoV-2 spike protein by D614G substitution
Science, 2021 How an early variant got ahead Throughout the COVID-19 pandemic, epidemiologists have monitored the evolution of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) with particular focus on the spike protein.
Jun Zhang +12 more
semanticscholar +1 more source
The SARS-CoV-2 spike protein is vulnerable to moderate electric fields
Nature Communications, 2021 The SARS-CoV-2 Spike protein is essential for viral infectivity and binds to the host receptor ACE2. Here, the authors present MD simulations of the Spike protein and its variants of concern and observe that the Spike protein is destabilised by moderate ...
Claudia R. Arbeitman +3 more
doaj +1 more source
Physiological sharp wave-ripples and interictal events in vitro: What’s the difference? [PDF]
, 2014 Sharp wave-ripples and interictal events are physiological and pathological forms of transient high activity in the hippocampus with similar features.
Freund, Tamás +7 more
core +1 more source