Results 31 to 40 of about 403,301 (348)

Structure of SARS-CoV-2 spike protein

open access: yesCurrent Opinion in Virology, 2021
The COVID-19 (coronavirus disease 2019) pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has led to loss of human life in millions and devastating socio-economic consequences worldwide. The disease has created urgent needs for intervention strategies to control the crisis and meeting these needs requires a deep ...
Jun Zhang   +3 more
openaire   +2 more sources

Spike protein of SARS-CoV-2 suppresses gonadotrophin secretion from bovine anterior pituitaries

open access: yesThe Journal of Reproduction and Development, 2022
Coronavirus disease (COVID-19), the ongoing global pandemic, is caused by the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). Recent evidence shows that the virus utilizes angiotensin-converting enzyme 2 (ACE2) as a spike protein receptor ...
Dimas Arya ABDILLAH   +4 more
doaj   +1 more source

SARS-CoV-2 Spike Protein Interaction Space

open access: yesInternational Journal of Molecular Sciences, 2023
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a +sense single-strand RNA virus. The virus has four major surface proteins: spike (S), envelope (E), membrane (M), and nucleocapsid (N), respectively. The constitutive proteins present a high grade of symmetry. Identifying a binding site is difficult. The virion is approximately 50–200 nm
Claudiu N. Lungu, Mihai V. Putz
openaire   +2 more sources

Binding of the SARS-CoV-2 Spike Protein to the Asialoglycoprotein Receptor on Human Primary Hepatocytes and Immortalized Hepatocyte-Like Cells by Confocal Analysis

open access: yesHepatic Medicine: Evidence and Research, 2021
Daniel P Collins,1 Clifford J Steer2,3 1CMDG, LLC, Saint Paul, MN, USA; 2Department of Medicine, University of Minnesota Medical School, Minneapolis, MN, USA; 3Department of Genetics, Cell Biology and Development, University of Minnesota Medical School ...
Collins DP, Steer CJ
doaj  

Accurate quantification of selenoproteins in human plasma/serum by isotope dilution ICP-MS : focus on selenoprotein P [PDF]

open access: yes, 2017
Acknowledgements The research leading to these results was funded by the EMRP Joint Research Project “Metrology for metalloproteins” (HLT-05 2012). The EMRP is jointly funded by the EMRP participating countries within EURAMET and the European Union.Peer ...
Busto, M. Estela del Castillo   +8 more
core   +1 more source

BSL2-compliant lethal mouse model of SARS-CoV-2 and variants of concern to evaluate therapeutics targeting the Spike protein

open access: yesFrontiers in Immunology, 2022
Since first reported in 2019, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is rapidly acquiring mutations, particularly in the spike protein, that can modulate pathogenicity, transmission and antibody evasion leading to successive waves ...
Mohanraj Manangeeswaran   +13 more
doaj   +1 more source

Mutations in the SARS CoV2 Spike Gene and Their Reflections on the Spike Protein

open access: yesClinical and Experimental Health Sciences, 2021
Objective: In this study, it was aimed to determine the mutation frequency in spike (S) genes of SARS CoV2 from six different regions of the world, their distribution on the gene and reflections of these mutations to the S protein. Materials and methods: SARS CoV2 S gene sequences originating from Asia, Africa, Europe, South America, Oceania and North ...
ÇAĞLAYAN, Elif, TURAN, Kadir
openaire   +3 more sources

SARS-CoV-2 Spike Protein Elicits Cell Signaling in Human Host Cells: Implications for Possible Consequences of COVID-19 Vaccines

open access: yesVaccines, 2021
The world is suffering from the coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). SARS-CoV-2 uses its spike protein to enter the host cells. Vaccines that introduce the spike protein into
Yuichiro J. Suzuki, Sergiy G. Gychka
doaj   +1 more source

Investigation of Interaction between the Spike Protein of SARS-CoV-2 and ACE2-Expressing Cells Using an In Vitro Cell Capturing System

open access: yesBiological Procedures Online, 2021
Background The Interaction between severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein with Angiotensin converting enzyme 2 (ACE2) on the host cells is a crucial step for the viral entry and infection.
Yuning Shang   +6 more
doaj   +1 more source

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