Results 231 to 240 of about 980,274 (295)

Cellular Responses to Mechanical Cues Across Scales: From Fundamental Insights to Translational Potential

Advanced Healthcare Materials, EarlyView.
This review examines how cellular behavior is regulated by mechanical cues transmitted through soft biomaterials, from single‐cell mechanosensing to tissue‐level adaptation. It highlights why physiological relevance, rather than model complexity alone, is critical for translational mechanobiology and introduces a scoring framework linking material ...
Mathias Polz, Manuel P. Kainz, Niklas Haider, Theresa Rienmüller, Kerstin Lenk, Rupert Kargl, Michele Terzano, Gerhard Sommer, Gerhard A. Holzapfel, Julia Fuchs   +9 more
wiley   +1 more source

Patient‐Derived 3D Heart‐On‐a‐Chip Model of Dilated Cardiomyopathy With Embedded Bead‐Based Mapping of Tissue Contractility

Advanced Healthcare Materials, EarlyView.
A heart‐on‐a‐chip model of dilated cardiomyopathy is developed from patient‐derived induced pluripotent stem cells. The model recapitulates key disease phenotypes and enables functional assessment through integrated bead‐based tracking and pillar deflection measurements.
Ali Mousavi, Ludovic Mouttet, Shihao Cui, Yasaman Hekmatnia, Mehran Mottahedi, Ida Derish, Naimeh Rafatian, Mark Aurousseau, Gregor Andelfinger, Renzo Cecere, Houman Savoji   +10 more
wiley   +1 more source

Concurrent Four-Dimensional Dynamic MRA and Perfusion Imaging Using Dual-Module Arterial Spin Labeling MRI With Stack-Of-Stars Golden-Angle Radial Acquisition. [PDF]

NMR Biomed
Zhao T, Tang J, Moum SJ, He Y, Huang Z, Khan A, Shaibani A, Yan L.   +7 more
europepmc   +1 more source

Engineered Microvascular Model of the Blood–Brain–Tumor Barrier Reveals Endothelial Remodeling in Diffuse Midline Glioma

Advanced Healthcare Materials, EarlyView.
We developed a patient‐derived, functional microfluidic model of the diffuse midline glioma (DMG) blood–brain–tumor barrier (BBTB) comprised of endothelial cells, astrocytes, pericytes, and tumor cells. The system forms perfusable microvasculature, reveals the BBTB retains vascular integrity, identifies DMG‐specific transcriptomic changes distinct from
Kimberly R. Bennett, Yann S. Vanrobaeys, Tessy Teboh, Zakiya Smith, Anderson Scott, Cynthia Hajal, Paula T. Hammond, Joelle P. Straehla   +7 more
wiley   +1 more source

Conjugated Porphyrin Polymer With Superior Charge Transfer for Photodynamic‐Immunomodulatory Prevention of CIED Infection in Diabetes

Advanced Healthcare Materials, EarlyView.
Under NIR irradiation, PTCPP generates ROS to eliminate MRSA biofilms and promote M1 macrophage polarization for phagocytosis. After bacterial clearance, the material is phagocytosed by macrophages, shifting their polarization to M2 phenotype via metabolic reprogramming, which synergistically enhances anti‐infection therapy and wound healing.
Honghao Ma, Jinguo Xu, Rongrong Gu, Chuanhui Dong, Te Chen, Yi Mu, Jing Zhu, Yating Wang, Wen Wang, Yingying Zhang, Hongyu Ma, Xiaochen Wang, Sheng Ye, Cheng Cheng   +13 more
wiley   +1 more source

A prognostic human brain network for diffuse midline glioma. [PDF]

Nature
Sidpra J, Lind V, Cohen AL, Schaper FLWVJ, Stone TJ, Grabovska Y, Biswas A, Sudhakar S, Sepulveda F, Peres BS, Veronese G, Alemán-Charlet C, Ogunbiyi O, Shamardani K, Zhao J, Palacin AC, Miller G, Opipari RS, De Vita E, Ridout D, Ferraciolli SF, Lucato LT, Avsenik J, Piccirilli E, Morales-La Madrid A, Muchart J, Ryan ME, Patel R, Haldipur P, Hill CS, Krüger MT, Zrinzo L, Jeelani NUO, Martinez-Barbera JP, Donson AM, Dorris K, Morgan PS, Mackay A, Venkatesh HS, Horn A, Mueller S, Green AL, Mirsky DM, Akram H, Jones C, Aquilina K, Mankad K, Monje M, Jacques TS, Fox MD, Hargrave DR.   +50 more
europepmc   +1 more source

Elliptical β-barrel deformation underlies gating in VDAC1. [PDF]

Protein Sci
Bergdoll L, Elgeti M, Belyaeva J, Zlobin A, Duneau JP, Hubbell W, Abramson J.   +6 more
europepmc   +1 more source

Quantifying Ligand-to-Protein Distances in Complex Environments Using Intermolecular ¹⁹F PRE NMR Spectroscopy. [PDF]

Chembiochem
Werle Y, Inderfurth ML, Lang CJ, Kovermann M.   +3 more
europepmc   +1 more source

Zn Complexes with the 4-Acyl-Pyrazol-5-One Basis and Their Thin Films. [PDF]

Int J Mol Sci
Gusev A, Braga E, Pismennaia A, Vlasenko V, Hasegawa M, Kiskin M, Linert W.   +6 more
europepmc   +1 more source

dHis-Cu(II) based EPR distances at W-band: navigating the challenges of excitation.

Phys Chem Chem Phys
Moriglioni NA, Limbach Y, El Mkami H, Hunter RI, Ackermann K, Smith GM, Bode BE, Saxena S.   +7 more
europepmc   +1 more source