Results 171 to 180 of about 437,835 (354)

PFOS Disrupts Oocyte Maturation and Early Embryonic Development via Ovarian FOXK1 O‐GlcNAcylation in Mice

Advanced Science, EarlyView.
Perfluorooctane sulfonate (PFOS) exposure disrupts oocyte maturation and early embryonic development. This study elucidates the mechanism by which enhanced O‐GlcNAcylation of FOXK1 underlies the PFOS‐induced reduction of progesterone levels in granulosa cells and the disturbance of follicular microenvironment.
Shuwen Han, Qin Yuan, Zhu Wu, Yaohui Fang, Hong Qian, Jiale Zhu, Yuchen Zhang, Ke Deng, Liangliang Su, Haibo Xu, Haotian Shu, Yiming Gong, Qiaoqiao Xu, Guizhen Du, Di Wu, Yun Fan, Chuncheng Lu   +16 more
wiley   +1 more source

CDK1 Inactivation Regulates Anaphase Spindle Dynamics and Cytokinesis In Vivo [PDF]

, 1997
Sally P. Wheatley, Edward H. Hinchcliffe, Michael Glotzer, Anthony A. Hyman, Greenfield Sluder, Yu-Li Wang   +5 more
openalex   +1 more source

NuSAP Safeguards Centriole Integrity to Mediate CEP57‐CEP152 Torus Recruitment for Proper Engagement

Advanced Science, EarlyView.
This study reveals a novel role for the microtubule stabilizer NuSAP at centrioles. NuSAP depletion destabilizes the centriole's tubulin structure, causing premature disengagement, PCM defects, and mis‐localization of the CEP57‐CEP63‐CEP152 complex. By reinforcing centriole architecture, NuSAP enables early CEP57 loading and initiates a newly proposed ...
Shiyu Zhang, Zemin Jiang, Qiaoyun Yang, Hong Zheng, Minghao Wang, Chennianci Zhu, Lih‐Wen Deng, Karen Carmelina Crasta, Yih‐Cherng Liou   +8 more
wiley   +1 more source

Inhibition of anaphase spindle elongation in vitro by a peptide antibody that recognizes kinesin motor domain.

, 1993
Christopher J. Hogan, Harrison Wein, Linda Wordeman, Jonathan M. Scholey, Kenneth E. Sawin, W. Zacheus Cande   +5 more
openalex   +2 more sources

The centrosome and mitotic spindle apparatus in cancer and senescence [PDF]

, 2010
Stephan Schmidt, Frank Eßmann, Ion Cristian Cirstea, Fabian Kuck, Harish C. Thakur, Madhurendra Singh, Anja Kletke, Reiner U. Jänicke, Constanze Wiek, Helmut Hanenberg, Mohammad Reza Ahmadian, Klaus Schulze‐Osthoff, Bernd Nürnberg, Roland P. Piekorz   +13 more
openalex   +1 more source

S3RL: Enhancing Spatial Single‐Cell Transcriptomics With Separable Representation Learning

Advanced Science, EarlyView.
Separable Spatial Representation Learning (S3RL) is introduced to enhance the reconstruction of spatial transcriptomic landscapes by disentangling spatial structure and gene expression semantics. By integrating multimodal inputs with graph‐based representation learning and hyperspherical prototype modeling, S3RL enables high‐fidelity spatial domain ...
Laiyi Fu, Penglei Wang, Gaoyuan Xu, Jitao Lu, Qinke Peng, Danyang Wu, Hequan Sun   +6 more
wiley   +1 more source

Isolation and characterization of mutants supersensitive to the spindle poison, Isopropyl N-3-chlorophenyl carbamate (CIPC) in the fission yeast Schizosaccharomyces pombe.

, 1992
Junpei Ishiguro, Yukiko UHARA
openalex   +2 more sources

Testicular protein Spag5 has similarity to mitotic spindle protein Deepest and binds outer dense fiber protein Odf1 [PDF]

, 2001
Xueping Shao, Jiaping Xue, Frans A. van der Hoorn   +2 more
openalex   +1 more source

Study on the Unbalanced Fault Dynamic Characteristics of Eccentric Motorized Spindle considering the Effect of Magnetic Pull [PDF]

, 2021
Zhan Wang, Wenzhi He, Siyuan Du, Zhe Yuan   +3 more
openalex   +1 more source

Radical‐Mediated, Substrate‐Independent Fabrication of Hybrid Solid–Hydrogel Materials With Tunable Crosslinking: An Initiator‐ and Crosslinker‐Free Approach

Advanced Science, EarlyView.
This work introduces a substrate‐independent, reagent‐free plasma strategy that forms radical‐rich interlayers for covalent hydrogel attachment without initiators or crosslinkers. The long‐lived radicals drive in situ gelation, creating robust, cytocompatible hybrid solid–hydrogel constructs across diverse substrates.
Ghazal Shineh, Azin Khodaei, Pardis Keikhosravani, Masoud Zhianmanesh, Yiyun Xia, Aaron Glimour, Sina Naficy, Andrea Guzina, Daniella Bianchi, Khoon s Lim, Fariba Dehghani, Saber Amin Yavari, Marcela Bilek, Giselle C. Yeo, Behnam Akhavan   +14 more
wiley   +1 more source