Results 61 to 70 of about 534,301 (305)
The turtle and the rabbit story in a modern (PI3)key
Molecular & Cellular Oncology, 2018 Mitosis is a complex process controlling proper distribution of chromosomes and preventing genomic instability, a typical hallmark of cancer. We recently reported that that a class II isoform of Phosphoinositide 3-kinase (PI3K), PI3K-C2α, is involved in ...
Miriam Martini +2 more
doaj +1 more source
Modeling Dual Pathways for the Metazoan Spindle Assembly Checkpoint [PDF]
, 2006 Using computational modelling, we investigate mechanisms of signal transduction focusing on the spindle assembly checkpoint where a single unattached kinetochore is able to signal to prevent cell cycle progression.
Acquaviva +29 more
core +3 more sources
Cortical dendritic activity correlates with spindle-rich oscillations during sleep in rodents
Nature Communications, 2017 How sleep influences brain plasticity is not known. In particular, why certain electroencephalographic (EEG) rhythms are linked to memory consolidation is poorly understood. Calcium activity in dendrites is known to be necessary for structural plasticity
J. Seibt +8 more
semanticscholar +1 more source
Mechanotransduction in the muscle spindle [PDF]
Pflügers Archiv - European Journal of Physiology, 2014 The focus of this review is on the principal sensory ending of the mammalian muscle spindle, known as the primary ending. The process of mechanosensory transduction in the primary ending is examined under five headings: (i) action potential responses to defined mechanical stimuli-representing the ending's input-output properties; (ii) the receptor ...
Bewick, Guy S., Banks, Robert W.
openaire +5 more sources
PASSIVE TORQUE SIMULATION OF SMALL ANGULAR CONTACT BEARING AT HIGH SPEED [PDF]
, 2017 Description of common ball bearing torque models was presented and adopted to the complex thermo-mechanical model of the high speed spindle. Ball bearing passive torque was measured on the own high-speed spindle design.
Kekula J., Smolík J., Sulitka M.
core +1 more source
Journal of Neural Transplantation and Plasticity, 2016 Several studies have identified two types of sleep spindles: fast (13–15 Hz) centroparietal and slow (11–13 Hz) frontal spindles. Alterations in spindle activity have been observed in Alzheimer's disease (AD) and Mild Cognitive Impairment (MCI). Only few
M. Gorgoni +12 more
semanticscholar +1 more source
The Journal of Cell Biology, 2006 The Xorbit microtubule-binding protein, say Hannak and Heald (page 19), keeps the spindle from getting away from its passenger DNA. Figure Dominant-negative Xorbit (green) results in short spindles and chromosome (blue) alignment defects. Xorbit is a spindle-localized microtubule plus-end binding protein whose loss causes defects in ...
openaire +2 more sources
Structural Organization and Function of the Golgi Ribbon During Cell Division
Frontiers in Cell and Developmental Biology, 2022 The Golgi complex has a central role in the secretory traffic. In vertebrate cells it is generally organized in polarized stacks of cisternae that are laterally connected by membranous tubules, forming a structure known as Golgi ribbon.
Inmaculada Ayala, Antonino Colanzi
doaj +1 more source
Ipl1/aurora kinase suppresses S-CDK-driven spindle formation during prophase I to ensure chromosome integrity during meiosis [PDF]
, 2013 Cells coordinate spindle formation with DNA repair and morphological modifications to chromosomes prior to their segregation to prevent cell division with damaged chromosomes.
A Hochwagen +51 more
core +3 more sources
The elegans of spindle assembly [PDF]
Cellular and Molecular Life Sciences, 2010 The Caenorhabditis elegans one-cell embryo is a powerful system in which to study microtubule organization because this large cell assembles both meiotic and mitotic spindles within the same cytoplasm over the course of 1 h in a stereotypical manner. The fertilized oocyte assembles two consecutive acentrosomal meiotic spindles that function to reduce ...
Eileen T. O'Toole +3 more
openaire +3 more sources