Results 41 to 50 of about 403,042 (304)
eLife, 2022 During anaphase B, molecular motors slide interpolar microtubules to elongate the mitotic spindle, contributing to the separation of chromosomes. However, sliding of antiparallel microtubules reduces their overlap, which may lead to spindle breakage ...
Manuel Lera-Ramirez +2 more
doaj +1 more source
BMC Genetics, 2011 Background Metaphase cells have short spindles for efficient bi-orientation of chromosomes. The cohesin proteins hold sister chromatids together, creating Sister Chromatid Cohesion (SCC) that helps in the maintenance of short spindle lengths in metaphase.
Sanyal Kaustuv +4 more
doaj +1 more source
Investigation of the Chemical Composition and Efficiency of Seed Oil of Spindle Tree (Euonymus Europaea L.) on the Model of Non-allergic Dermatitis [PDF]
, 2018 The aim of the research was to study the chemical composition and effectiveness of the seed oil of Spindle tree (Euonymus europaea L.) on the non-allergic contact dermatitis model.The oil was obtained by the extraction by petroleum ether from the seeds ...
Vrubel, O. (Olha) +2 more
core +2 more sources
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Kaposiform lymphangiomatosis (KLA) is an aggressive complex lymphatic anomaly. Patients exhibit malformed lymphatic vessels and often develop hemorrhagic effusions and elevated angiopoietin‐2 (Ang‐2) levels. A somatic NRAS p.Q61R (NRASQ61R) mutation has been associated with KLA.
C. Griffin McDaniel +3 more
wiley +1 more source
Animals, 2023 F-actin is of critical importance in oocyte meiotic maturation. Actin assembly and its dynamics are mainly regulated by actin nucleation factors. The actin-related protein complex 2/3 (Arp2/3) is responsible for the organization of F-actin filaments ...
Meng-Hao Pan +11 more
doaj +1 more source
Spindle configurations of skew lines
, 2004 We prove a conjecture of Crapo and Penne which characterizes isotopy classes of skew configurations with spindle-structure. We use this result in order to define an invariant, spindle-genus, for spindle-configurations.
Borobia +11 more
core +2 more sources
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Non-REM Sleep Characteristics Predict Early Cognitive Impairment in an Aging Population
Frontiers in Neurology, 2019 Objective: Recent research suggests that sleep disorders or changes in sleep stages or EEG waveform precede over time the onset of the clinical signs of pathological cognitive impairment (e.g., Alzheimer's disease).
Jacques Taillard +18 more
doaj +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Strong static magnetic field delayed the early development of zebrafish [PDF]
Open Biology, 2019 One of the major topics in magnetobiology is the biological effects of strong static magnetic field (SMF) on living organisms. However, there has been a paucity of the comprehensive study of the long-term effects of strong SMF on an animal's development.
Shuchao Ge +6 more
doaj +1 more source