NuMA recruits dynein activity to microtubule minus-ends at mitosis
eLife, 2017 To build the spindle at mitosis, motors exert spatially regulated forces on microtubules. We know that dynein pulls on mammalian spindle microtubule minus-ends, and this localized activity at ends is predicted to allow dynein to cluster microtubules into
Christina L Hueschen +3 more
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Three-dimensional structure of kinetochore-fibers in human mitotic spindles
eLife, 2022 During cell division, kinetochore microtubules (KMTs) provide a physical linkage between the chromosomes and the rest of the spindle. KMTs in mammalian cells are organized into bundles, so-called kinetochore-fibers (k-fibers), but the ultrastructure of ...
Robert Kiewisz +5 more
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Practical Estimation of Machine Tool Spindle Dynamics for Maintenance Decision Making
Applied SciencesCondition-based maintenance of a machine tool spindle unit is known to reduce the total cost of operation in a manufacturing environment. However, standard vibration monitoring thresholds, which are based only on average vibration energy levels, do not ...
Patrick Chin +2 more
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Live cell imaging of meiosis in Arabidopsis thaliana
eLife, 2019 To follow the dynamics of meiosis in the model plant Arabidopsis, we have established a live cell imaging setup to observe male meiocytes. Our method is based on the concomitant visualization of microtubules (MTs) and a meiotic cohesin subunit that ...
Maria A Prusicki +8 more
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Afadin orients cell division to position the tubule lumen in developing renal tubules [PDF]
, 2017 In many types of tubules, continuity of the lumen is paramount to tubular function, yet how tubules generate lumen continuity in vivo is not known. We recently found the F-actin binding protein Afadin is required for lumen continuity in developing renal ...
Brakeman, Paul R. +9 more
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Frontiers in Neurology, 2022 PurposeInterictal epileptic discharges (IEDs) are known to affect cognitive function in patients with epilepsy, but the mechanism has not been elucidated.
Toshiki Okadome +8 more
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A comparative study of using spindle motor power and eddy current for the detection of tool conditions in milling processes [PDF]
, 2015 This paper investigates the use of the power of the driving motor of a CNC spindle in comparison to two perpendicular eddy current sensors for the detection of tool wear in milling processes. Monitoring the power through the current profile is a low cost
Abbass, JK, Al-Habaibeh, A
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PREDICTION THE EVOLUTION OF TEMPERATURE AND VIBRATIONS ON SPINDLE USING ARTIFICIAL NEURAL NETWORKS AND FUZZY LOGIC [PDF]
Annals: Series on engineering sciences (Academy of Romanian Scientists), 2016 Simulation spindle behavior in terms of temperature and vibration at higher speeds is more economical and more secure (avoid undesirable mechanical events) than testing practice.
Daniel Petru GHENCEA +2 more
doaj
Digital Twin-Driven Thermal Error Prediction for CNC Machine Tool Spindle
Lubricants, 2023 Traditional methods for predicting thermal error ignore the correlation between physical world data and virtual world data, leading to the low prediction accuracy of thermal errors and affecting the normal processing of the CNC machine tool (CNCMT ...
Quanbo Lu, Dong Zhu, Meng Wang, Mei Li
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A comparison of the distribution of actin and tubulin in the mammalian mitotic spindle as seen by indirect immunofluorescence [PDF]
, 1977 Rabbit antibodies against actin and tubulin were used in an indirect immunofluorescence study of the structure of the mitotic spindle of PtK1 cells after lysis under conditions that preserve anaphase chromosome movement. During early prophase there is no
Cande, W. Zacheus +2 more
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