Results 21 to 30 of about 403,042 (304)

Retroperitoneal spindle cell variant of embryonal rhabdomyosarcoma in a child

open access: yesMedical Journal of Dr. D.Y. Patil Vidyapeeth, 2019
Spindle cell rhabdomyosarcoma (RMS) is a rare variant of embryonal RMS that has a predilection for young males and most commonly involves the paratesticular region followed by the head and neck.
Aditya Pratap Singh   +3 more
doaj   +1 more source

Excess TPX2 Interferes with Microtubule Disassembly and Nuclei Reformation at Mitotic Exit

open access: yesCells, 2020
The microtubule-associated protein TPX2 is a key mitotic regulator that contributes through distinct pathways to spindle assembly. A well-characterised function of TPX2 is the activation, stabilisation and spindle localisation of the Aurora-A kinase ...
Francesco D. Naso   +9 more
doaj   +1 more source

Coupling between motor cortex and striatum increases during sleep over long-term skill learning

open access: yeseLife, 2021
The strength of cortical connectivity to the striatum influences the balance between behavioral variability and stability. Learning to consistently produce a skilled action requires plasticity in corticostriatal connectivity associated with repeated ...
Stefan M Lemke   +5 more
doaj   +1 more source

The nucleolar RNA methyltransferase Misu (NSun2) is required for mitotic spindle stability [PDF]

open access: yes, 2009
Myc-induced SUN domain–containing protein (Misu or NSun2) is a nucleolar RNA methyltransferase important for c-Myc–induced proliferation in skin, but the mechanisms by which Misu contributes to cell cycle progression are unknown.
Shobbir Hussain   +49 more
core   +1 more source

PASSIVE TORQUE SIMULATION OF SMALL ANGULAR CONTACT BEARING AT HIGH SPEED [PDF]

open access: yes, 2017
Description of common ball bearing torque models was presented and adopted to the complex thermo-mechanical model of the high speed spindle. Ball bearing passive torque was measured on the own high-speed spindle design.
Kekula J., Smolík J., Sulitka M.
core   +1 more source

The Development of a Monitoring System Using a Wireless and Powerless Sensing Node Deployed Inside a Spindle

open access: yesSensors, 2011
Installation of a Wireless and Powerless Sensing Node (WPSN) inside a spindle enables the direct transmission of monitoring signals through a metal case of a certain thickness instead of the traditional method of using connecting cables.
Da-Sheng Lee, Liang-Cheng Chang
doaj   +1 more source

Loss of PDK1 Induces Meiotic Defects in Oocytes From Diabetic Mice

open access: yesFrontiers in Cell and Developmental Biology, 2021
Maternal diabetes has been shown to impair oocyte quality; however, the underlying mechanisms remain unclear. Here, using a streptozotocin (STZ)-induced diabetic mouse model, we first detected and reduced expression of pyruvate dehydrogenase kinase 1 ...
Juan Ge   +8 more
doaj   +1 more source

Anaphase B. [PDF]

open access: yes, 2016
Anaphase B spindle elongation is characterized by the sliding apart of overlapping antiparallel interpolar (ip) microtubules (MTs) as the two opposite spindle poles separate, pulling along disjoined sister chromatids, thereby contributing to chromosome ...
Brust-Mascher, Ingrid   +2 more
core   +2 more sources

The spindle checkpoint [PDF]

open access: yesJournal of Cell Science, 2006
Every mitosis, replicated chromosomes must be accurately segregated into each daughter cell. Pairs of sister chromatids attach to the bipolar mitotic spindle during prometaphase, they are aligned at metaphase, then sisters separate and are pulled to opposite poles during anaphase.
Karen M, May, Kevin G, Hardwick
openaire   +2 more sources

Spindle pole bodies [PDF]

open access: yesCurrent Biology, 2013
What is a spindle pole body? The spindle pole body (SPB) or duplication plaque of fungi is the functional equivalent of the centrosome in higher eukaryotes. SPBs serve as microtubule organizing centres (MTOCs), sites where microtubules (MTs) are assembled from tubulin subunits. In contrast to centrosomes, SPBs do not contain centrioles.
Seybold, Christian, Schiebel, Elmar
openaire   +2 more sources

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