Results 101 to 110 of about 995,356 (273)

Bioinspired Directional Hydrogel‐Based High‐Performance Flexible Sensor for Multiple Jumping Pattern Detection in Athletic Training

Advanced Science, EarlyView.
This study develops a bioinspired directional hydrogel (BDH) via flow‐induced alignment of polyvinyl alcohol and dispersed carbon nanotubes, enhanced by the immersion of natural moisturizing factors. The BDH exhibits superior mechanical strength, conductivity, and moisture retention, enabling high‐performance flexible sensors for precise motion ...
Hanqi Wang, Sen Wang, Yirong Jiang, Zhehao Han, Da Lin, Qinglu Luo, Tianqi Fu, Hanyi Zhang, Deshuai Yu, Jia Yi, Yan Hu, Youhui Lin   +11 more
wiley   +1 more source

Emerging role and function of SPDL1 in human health and diseases

Open Medicine
SPDL1 (spindle apparatus coiled-coil protein 1), also referred to as CCDC99, is a recently identified gene involved in cell cycle regulation. SPDL1 encodes a protein, hSpindly, which plays a critical role in the maintenance of spindle checkpoint ...
Feng Yuejiao, Tang Donghao, Wang Jie
doaj   +1 more source

Biomimetic Nanomedicine for Senescence‐Modulated Immune Activation Enhances Immunotherapy Efficacy in Hepatocellular Carcinoma

Advanced Science, EarlyView.
A multifunctional mPDZM nanoplatform is developed in this study. mPDZM integrates chemotherapy‐induced senescence, selective senolysis, and STING‐mediated immune activation. mPDZM effectively clears senescent tumor cells, remodels the tumor immune microenvironment, and enhances antitumor T‐cell responses.
Shiji Fang, Liyun Zheng, Bin Lin, Jiale Chen, Dehai Hou, Yiming Ding, Mengzhu Han, Pan Qin, Mengyuan Wang, Xiaoju Guo, Yeyu Zhang, Gaofeng Shu, Fazong Wu, Jianfei Tu, Minjiang Chen, Zhongwei Zhao, Zhuang Liu, Jiansong Ji   +17 more
wiley   +1 more source

Clinically Informed Intelligent Classification of Ovarian Cancer Cells by Label‐Free Holographic Imaging Flow Cytometry

Advanced Intelligent Systems, Volume 7, Issue 3, March 2025.
Quantitative phase maps of single cells recorded in flow cytometry modality feed a hierarchical architecture of machine learning models for the label‐free identification of subtypes of ovarian cancer. The employment of a priori clinical information improves the classification performance, thus emulating the clinical application of liquid biopsy during ...
Daniele Pirone, Beatrice Cavina, Daniele Gaetano Sirico, Martina Mugnano, Vittorio Bianco, Lisa Miccio, Anna Myriam Perrone, Anna Maria Porcelli, Giuseppe Gasparre, Ivana Kurelac, Pasquale Memmolo, Pietro Ferraro   +11 more
wiley   +1 more source

Eg5 UFMylation promotes spindle organization during mitosis

Cell Death and Disease
UFMylation is a highly conserved ubiquitin-like post-translational modification that catalyzes the covalent linkage of UFM1 to its target proteins. This modification plays a critical role in the maintenance of endoplasmic reticulum proteostasis, DNA ...
Guangxu Li, Yuanjiang Huang, Wenbo Han, Liyi Wei, Hongjing Huang, Yingbao Zhu, Qiao Xiao, Zujia Wang, Wen Huang, Ranhui Duan   +9 more
doaj   +1 more source

Disruption of Plasmodium falciparum kinetochore proteins destabilises the nexus between the centrosome equivalent and the mitotic apparatus

Nature Communications
Plasmodium falciparum is the causative agent of malaria and remains a pathogen of global importance. Asexual blood stage replication, via a process called schizogony, is an important target for the development of new antimalarials.
Jia-huang Li, Gerald J. Shami, Benjamin Liffner, Ellie Cho, Filip Braet, Manoj T. Duraisingh, Sabrina Absalon, Matthew W A Dixon, Leann Tilley   +8 more
semanticscholar   +1 more source

Printed Zinc Tin Oxide Memristors for Reservoir Computing

Advanced Intelligent Systems, EarlyView.
Fully patterned zinc tin oxide memristors produced mostly with printing techniques that is programmed for physical reservoir computing. MNIST handwriting dataset is used to program the memristor and a 4‐bit and a 5‐bit cell. In this work, fully patterned zinc tin oxide (ZTO) memristors are introduced using inkjet printing.
Raquel Azevedo Martins, Carlos Silva, Jonas Deuermeier, Gianluca Milano, Mateo Rosero‐Realpe, Carolina Parreira, Elvira Fortunato, Rodrigo Martins, Asal Kiazadeh, Emanuel Carlos   +9 more
wiley   +1 more source

Custom Shape Formation in Continuum Robots Using Compliant Bistable Segments for Medical Applications

Advanced Intelligent Systems, EarlyView.
This article describes the integration of compliant bi‐stability in continuum robots. This integration leads to two variants of compliant bistable mechanism (CBM) integrated continuum robot segments, extending and locking. Results show that when used together, these CBM‐integrated segments allow the continuum robot to form custom shapes.
Muhammad Umer Khan Niazi, Usman Mehmood, Jaesoon Choi, Yoon Se Lee, Youngjin Moon   +4 more
wiley   +1 more source

Fig-S1 from Mitotic Spindle Apparatus Abnormalities in Chronic Obstructive Pulmonary Disease Cells: A Potential Pathway to Lung Cancer [PDF]

, 2023
Jose Thaiparambil, Lingyun Dong, Diana Jasso, Jian‐An Huang, Randa El‐Zein   +4 more
openalex   +2 more sources

Loss of spatial control of the mitotic spindle apparatus in a Chlamydomonas reinhardtii mutant strain lacking basal bodies. [PDF]

, 1995
Linda L. Ehler, Jeffrey Holmes, Susan K. Dutcher   +2 more
openalex   +1 more source