Results 201 to 210 of about 58,631 (285)
The Journal of Physiology, EarlyView.Abstract figure legend Schematic outlining the activation of hypoxia‐sensitive pathways, the influence of hypoxia and associated pathways on the cytoskeleton, and the impact of these on disease progression. Abstract A highly‐regulated and dynamic cytoskeleton is vital for functional cellular physiology and the maintenance of homeostasis.
Darragh Flood, Cormac T. Taylor
wiley +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend Regulatory mechanisms such as alternative splicing, post‐translational modification, membrane trafficking, and protein interactions control channel gating, membrane abundance, and overall activity of PIEZO2. Proper regulation supports PIEZO2‐dependent proprioceptive, somatosensory, nociceptive, pruriceptive and interoceptive ...
Eunice I. Oribamise +2 more
wiley +1 more source
A minimal deterministic model reveals integration of spindle assembly and position checkpoints in mitosis. [PDF]
Sci RepIbrahim B.
europepmc +1 more source
Scheduling optimization of optical lens polishing
International Transactions in Operational Research, Volume 33, Issue 6, Page 3744-3768, November 2026.Abstract Optical systems have achieved notable progress in focusing and imaging technologies; however, manual grinding remains indispensable, resulting in elevated costs, extended timelines, and inefficiencies. These difficulties are compounded by operational constraints, uneven machine utilization, and risks of order delays and escalating expenses ...
Tzu‐Chin Lin, Bertrand M. T. Lin
wiley +1 more source
PP6 phosphatase and Elongator contribute to kinesin 5-dependent spindle assembly by controlling microtubule regulators levels. [PDF]
PLoS GenetMarín L +9 more
europepmc +1 more source
A Quarter Century of EHD Protein Research: From Endosomal Recycling to Ciliopathies
Traffic, Volume 27, Issue 3, September 2026.Human EHD protein subcellular localization. ABSTRACT Eps15 homology domain‐containing proteins comprise a conserved family of membrane‐remodeling ATPases that regulate endocytic trafficking, membrane fission, receptor recycling, primary ciliogenesis and membrane dynamics across eukaryotes. Since the initial identification of EHD1 and its Caenorhabditis
Devin Frisby +3 more
wiley +1 more source
The Secret (Mitotic) Life of Clathrin
Traffic, Volume 27, Issue 3, September 2026.A perspective on the function of clathrin at the mitotic spindle during cell division. ABSTRACT The discovery of clathrin was a foundational event in membrane traffic research. Its identification as the major protein component of the coat that surrounds endocytic vesicles kickstarted the biochemical and molecular characterization of endocytosis. During
Stephen J. Royle
wiley +1 more source
Role of spindle assembly checkpoint proteins in gametogenesis and embryogenesis. [PDF]
Front Cell Dev BiolPun R, North BJ.
europepmc +1 more source
Hypoxia Induces a Mitotic Survival Advantage After Radiotherapy in Head and Neck Cancer Cells
International Journal of Cancer, Volume 159, Issue 4, Page 1042-1055, 15 August 2026.Hypoxic tumor environments significantly limit radiotherapy effectiveness against cancer, particularly in head and neck squamous cell carcinoma (HNSCC). Here, the authors tracked hypoxic and post‐hypoxic cells using a hypoxia‐fate mapping system in human papillomavirus (HPV)‐positive and HPV‐negative HNSCC models.
Marilyn Wegge +3 more
wiley +1 more source
19S proteasome loss regulates mitotic spindle assembly through a ubiquitin-independent degradation mechanism. [PDF]
Cell RepMarescal O, Cheeseman IM.
europepmc +1 more source