Kinesin KIF3A regulates meiotic progression and spindle assembly in oocyte meiosis. [PDF]
Liu JC +7 more
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Kinesin-5/Cut7 C-terminal tail phosphorylation is essential for microtubule sliding force and bipolar mitotic spindle assembly. [PDF]
Jones MH +4 more
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Targeting the EGFR and Spindle Assembly Checkpoint Pathways in Oral Cancer: A Plausible Alliance to Enhance Cell Death. [PDF]
Calheiros-Lobo M +7 more
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Exploring the Therapeutic Implications of Co-Targeting the EGFR and Spindle Assembly Checkpoint Pathways in Oral Cancer. [PDF]
Calheiros-Lobo M +5 more
europepmc +1 more source
Correction for Deng et al., A coadapted KNL1 and spindle assembly checkpoint axis orchestrates precise mitosis in Arabidopsis. [PDF]
europepmc +1 more source
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Spindle Assembly and Mitosis in Plants
Annual Review of Plant Biology, 2022In contrast to well-studied fungal and animal cells, plant cells assemble bipolar spindles that exhibit a great deal of plasticity in the absence of structurally defined microtubule-organizing centers like the centrosome. While plants employ some evolutionarily conserved proteins to regulate spindle morphogenesis and remodeling, many essential spindle
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Mechanisms underlying spindle assembly and robustness
The microtubule-based spindle orchestrates chromosome segregation during cell division. Following more than a century of study, many components and pathways contributing to spindle assembly have been described, but how the spindle robustly assembles remains incompletely understood.
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Spindle assembly checkpoint: the third decade [PDF]
The spindle assembly checkpoint controls cell cycle progression during mitosis, synchronizing it with the attachment of chromosomes to spindle microtubules. After the discovery of the mitotic arrest deficient ( MAD ) and budding ...
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The Spindle Assembly and Spindle Position Checkpoints
Annual Review of Genetics, 2003▪ Abstract  The mitotic spindle segregates chromosomes to opposite ends of the cell in preparation for cell division. Chromosome attachment to the spindle is monitored by the spindle assembly checkpoint, and at least in yeast cells, penetration of one spindle pole into the bud is monitored by the spindle position checkpoint.
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The spindle assembly checkpoint
Current Opinion in Cell Biology, 1996The spindle assembly checkpoint monitors proper chromosome attachment to spindle microtubules and is conserved from yeast to humans. Checkpoint components reside on kinetochores of chromosomes and show changes in phosphorylation and localization as cells proceed through mitosis.
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