Loss of the puromycin-sensitive aminopeptidase, PAM-1, triggers the spindle assembly checkpoint during the first mitotic division in Caenorhabditis elegans. [PDF]
Durkan A, Koup A, Bell SE, Lyczak R.
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The Arabidopsis BUB1/MAD3 family protein BMF3 requires BUB3.3 to recruit CDC20 to kinetochores in spindle assembly checkpoint signaling. [PDF]
Deng X +5 more
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Retraction Note: The long noncoding RNA CRYBG3 induces aneuploidy by interfering with spindle assembly checkpoint via direct binding with Bub3. [PDF]
Guo Z +14 more
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Correction for Deng et al., The <i>Arabidopsis</i> BUB1/MAD3 family protein BMF3 requires BUB3.3 to recruit CDC20 to kinetochores in spindle assembly checkpoint signaling. [PDF]
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Repurposing Suan-Zao-Ren-Tang as anticancer agents in apoptotic sensitization against non-small cell lung cancer cell lines through amplification of spindle assembly checkpoint activation. [PDF]
Hsiao YC +7 more
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The spindle-assembly checkpoint in space and time
In eukaryotes, the spindle-assembly checkpoint ( SAC) is a ubiquitous safety device that ensures the fidelity of chromosome segregation in mitosis.
Andrea Musacchio, Edward D Salmon
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Spindle assembly checkpoint: the third decade [PDF]
The spindle assembly checkpoint controls cell cycle progression during mitosis, synchronizing it with the attachment of chromosomes to spindle microtubules. After the discovery of the mitotic arrest deficient ( MAD ) and budding ...
Andrea Musacchio
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The spindle assembly checkpoint
Current Opinion in Cell Biology, 1996The spindle assembly checkpoint monitors proper chromosome attachment to spindle microtubules and is conserved from yeast to humans. Checkpoint components reside on kinetochores of chromosomes and show changes in phosphorylation and localization as cells proceed through mitosis.
A D, Rudner, A W, Murray
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A quantitative systems view of the spindle assembly checkpoint [PDF]
The idle assembly checkpoint acts to delay chromosome segregation until all duplicated sister chromatids are captured by the mitotic spindle. This pathway ensures that each daughter cell receives a complete copy of the genome. The high fidelity and robustness of this process have made it a subject of intense study in both the experimental and ...
Jagesh V Shāh
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