Results 151 to 160 of about 303,580 (303)

KEN-Box-dependent Degradation of the Bub1 Spindle Checkpoint Kinase by the Anaphase-promoting Complex/Cyclosome [PDF]

, 2006
Wei Qi, Hongtao Yu
openalex   +1 more source

The spindle assembly checkpoint is a therapeutic vulnerability of CDK4/6 inhibitor-resistant ER+ breast cancer with mitotic aberrations

, 2022
Isabel Soria‐Bretones, Kelsie L. Thu, Jennifer Silvester, Jennifer Cruickshank, Samah El Ghamrasni, Wail Ba-Alawi, Graham C. Fletcher, Reza Kiarash, Mitchell J. Elliott, Jordan J. Chalmers, Andrea C. Elia, Albert Cheng, April A. N. Rose, Mark R. Bray, Benjamin Haibe‐Kains, Tak W. Mak, David W. Cescon   +16 more
openalex   +1 more source

A Novel FGFR3‐Targeting Antibody‐Drug Conjugate Induces Tumor Cell Apoptosis through the cGAS–STING Pathway in Bladder Cancer

Advanced Science, Volume 13, Issue 4, 19 January 2026.
LZU‐WZLYCS01 is a novel FGFR3‐targeting ADC for bladder cancer with 7‐ethyl‐9‐fluorocamptothecin (A2) as its cytotoxic payload. LZU‐WZLYCS01 intracellularly releases A2, which targets MAD2L1 to activate the cGAS‐STING pathway and induce tumor cell apoptosis.
Shu Cui, Xiongfei Luo, Guangrui Fan, Jingqi Jiang, Yingru Wang, Enguang Yang, Jinpeng Ma, Ze Zhang, Yuhan Wang, Juan Wang, Dengtuo Wang, Hanzhang Wang, Liang Cheng, Junqiang Tian, Zhilong Dong, Yingqian Liu, Zhiping Wang   +16 more
wiley   +1 more source

Spindle checkpoint: trapped by the corona, cyclin B1 goes MAD. [PDF]

EMBO J, 2020
Conde C, Gassmann R.
europepmc   +1 more source

Function of Drg1/Rit42 in p53-dependent Mitotic Spindle Checkpoint [PDF]

, 2004
Kyung‐Tae Kim, Pat P. Ongusaha, Young‐Kwon Hong, Siavash K. Kurdistani, Masafumi Nakamura, Kun Ping Lu, Sam W. Lee   +6 more
openalex   +1 more source

Evolutionary Dynamics of the Spindle Assembly Checkpoint in Eukaryotes

Current Biology, 2020
G. Kops, B. Snel, E. Tromer
semanticscholar   +1 more source

Arid1a Deficiency Drives Aristolochic Acid‐Induced Liver Tumorigenesis through Ctnnb1 Mutation and Defective Nucleotide Excision Repair

Advanced Science, Volume 13, Issue 3, 14 January 2026.
ARID1A is frequently mutated in both non‐malignant tissues and cancers, but its role in tumor development after exposure to genotoxic carcinogen remains unclear. It is found that aristolochic acid I accelerated liver tumorigenesis in ARID1A‐deficient context by impairing nucleotide excision repair and enhancing carcinogen bioactivation, revealing key ...
Lan Wang, Shi‐Hao Bai, Shu‐Jin Song, Xiao‐Li Zhang, Xue‐Ying Shang, Zhao‐Ning Lu, Xiao‐Fang Cui, Xin‐Le Zhu, Ze‐Guang Han   +8 more
wiley   +1 more source

The conserved AAA-ATPase PCH-2 ^TRIP13 regulates spindle checkpoint strength. [PDF]

Mol Biol Cell, 2020
Défachelles L, Russo AE, Nelson CR, Bhalla N.   +3 more
europepmc   +1 more source

Spindle assembly checkpoint and chromosome stability in Caenorhabditis elegans

, 2009
Maja Tarailo‐Graovac
openalex   +1 more source

The yeast nuclear pore complex functionally interacts with components of the spindle assembly checkpoint [PDF]

, 2002
Tatiana Iouk, Oliver Kerscher, Robert J. Scott, Munira A. Basrai, Richard W. Wozniak   +4 more
openalex   +1 more source