Results 161 to 170 of about 303,580 (303)

In Situ Assembly of Transformable Monopeptide on Activated Neutrophils Attenuates NETs‐Induced Hepatocellular Carcinoma Metastasis by Disrupting NE Nuclear Translocation

Advanced Science, Volume 13, Issue 1, 5 January 2026.
Activated neutrophils release extracellular traps (NETs) that promote tumor metastasis. FTP‐NPs are develpoed, a peptidic nanomaterial that binds NE on neutrophil membranes, forming NE‐fibril clusters that deactivate NE and prevent NETs formation. This strategy reduces metastasis and enhances the anti‐tumor immune response by targeting NE subcellular ...
Yichi Chen, Yijun Wang, Haitao Shang, Jiayue Qiu, Ruotian Zhang, Yuxiang Xiong, Tong Wang, Fengyi Wang, Anbang Wu, Xin Lin, Bolin Wu, Chen Huang, Wen Cheng, Lu Zhang   +13 more
wiley   +1 more source

Sinonasal Sarcomas Management: An International Consensus Statement

International Forum of Allergy &Rhinology, Volume 16, Issue 1, Page 55-69, January 2026.
ABSTRACT Introduction Sinonasal sarcomas are exceedingly rare entities, constituting less than 7% of head and neck sarcomas. Their complex histology needs specialized treatment, which is often based on multimodal approaches including surgery, radiation therapy, and/or chemotherapy.
Alessandro Vinciguerra, Francesca Caspani, Marco Valentini, Anna Maria Camarda, Salvatore Provenzano, Eric W. Wang, Cem Meço, Marco Ferrari, Pavol Surda, Semi Harrabi, Fernando Augusto Batista Campos, Javier Martin Broto, B. Ashleigh Guadagnolo, Pierina Navarria, Ali Hosni, Nadia Hindi, Antoine Italiano, Daniel M. Trifiletti, Bernd Kasper, Benjamin Verillaud, Alberto Schreiber, Paolo Castelnuovo, Piero Nicolai, Iacopo Dallan, Matias Chacon, Shirley Y. Su, Juliette Thariat, Claudia Valverde, Matt Lechner, Jean Yves Blay, Maria Rosaria Fiore, Jean Anderson Eloy, Mehdi Brahmi, James N. Palmer, Victor Castro Oliden, Daniela Greto, Iwona Lugowska, Angelo Paolo Dei Tos, Thibaut van Zele, Alkis J. Psaltis, Paolo Giovanni Casali, Armelle Dufresne, Claudia Sangalli, Christos Georgalas, Ester Orlandi, Peter‐John Wormald, Philippe Herman, Ricardo Carrau, Ehab Y. Hanna, Lisa Licitra, Mario Turri‐Zanoni, Paolo Battaglia   +51 more
wiley   +1 more source

Yeast Sphingolipid Phospholipase Gene ISC1 Regulates the Spindle Checkpoint by a CDC55-Dependent Mechanism. [PDF]

Mol Cell Biol, 2020
Matmati N, Hassan BH, Ren J, Shamssedine AA, Jeong E, Shariff B, Snider J, Rødkær SV, Chen G, Mohanty BK, Zheng WJ, Obeid LM, Røssel-Larsen M, Færgeman NJ, Hannun YA.   +14 more
europepmc   +1 more source

Evidence that Aurora B is implicated in spindle checkpoint signalling independently of error correction

, 2011
Stefano Santaguida, Claudio Vernieri, Fabrizio Villa, Andrea Ciliberto, Arianna Esposito Verza   +4 more
openalex   +2 more sources

Protein Kinase C Regulates Meiosis in Mammalian Oocytes

BioEssays, Volume 48, Issue 1, January 2026.
Protein kinase C (PKC) participates in the regulation of mammalian oocyte meiosis. PKC is involved in meiosis resumption in prophase I and in the stabilization of meiosis I and meiosis II spindles. PKC stimulates the maturation‐promoting factor during fertilization and stabilizes the mitotic spindle during early embryo development. ABSTRACT The protein
Jaroslav Kalous, Fatima J. Berro, Lucie Nemcova   +2 more
wiley   +1 more source

Dynamics of spindle assembly and position checkpoints: Integrating molecular mechanisms with computational models

Computational and Structural Biotechnology Journal
Mitotic checkpoints orchestrate cell division through intricate molecular networks that ensure genomic stability. While experimental research has uncovered key aspects of checkpoint function, the complexity of protein interactions and spatial dynamics ...
Bashar Ibrahim
doaj   +1 more source

The Double Face of Base Excision Repair: Preventing and Triggering Double‐Strand Breaks

BioEssays, Volume 48, Issue 1, January 2026.
Base excision repair is conserved from bacteria to man, robustly eliminating oxidized bases in DNA and reinserting the appropriate nucleotide to restore an intact double helix. Recent results describe conditions and mechanisms that misregulate long‐patch BER to generate double‐strand breaks, triggering chromosome fragmentation and cell death, altering ...
Susan M. Gasser
wiley   +1 more source

Spindle Checkpoint Protein Xmad1 Recruits Xmad2 to Unattached Kinetochores [PDF]

, 1998
Rey‐Huei Chen, Andrej Shevchenko, Matthias Mann, Andrew W. Murray   +3 more
openalex   +1 more source

Evaluation of the Spindle Assembly Checkpoint Integrity in Mouse Oocytes [PDF]

, 2022
Mansour Aboelenain, Karen Schindler, Cecilia S. Blengini   +2 more
openalex   +1 more source

Where, When, and How? Integrating Spatiotemporal Cues in Cell Division

BioEssays, Volume 48, Issue 1, January 2026.
Accurate chromosome segregation during mitosis depends on the spatial and temporal regulation of spindle assembly, kinetochore‐microtubule attachment, and checkpoint signaling. Here, we highlight how mitotic chromosomes can serve as dynamic hubs that integrate molecular cues to coordinate spindle organization and timing, ensuring faithful genome ...
Luca Cirillo, Hradini Konthalapalli, Claudio Alfieri, Jonathon Pines   +3 more
wiley   +1 more source