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Spindle checkpoint proteins and chromosome–microtubule attachment in budding yeast [PDF]
Emily S. Gillett+2 more
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Crosstalk of the mitotic spindle assembly checkpoint with p53 to prevent polyploidy
Celia Vogel+4 more
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The spindle-assembly checkpoint in space and time
Nature Reviews Molecular Cell Biology, 2007In eukaryotes, the spindle-assembly checkpoint (SAC) is a ubiquitous safety device that ensures the fidelity of chromosome segregation in mitosis. The SAC prevents chromosome mis-segregation and aneuploidy, and its dysfunction is implicated in tumorigenesis. Recent molecular analyses have begun to shed light on the complex interaction of the checkpoint
Andrea Musacchio, Maria Giordano
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