Results 181 to 190 of about 303,580 (303)
The modified calycosin derivative H10 was more effective in inhibiting cell proliferation through G0/G1 cell cycle arrest, together with inhibiting the migration and colony formation abilities of ovarian cancer cell lines SKOV3 and A2780. Comparative proteomic analysis coupled with Ingenuity Pathway Analysis further delineated calycosin derivative H10 ...
Fuhong Yang +8 more
wiley +1 more source
Plk1 regulates PICH, a centromere-associated SNF2 family tranlocase that is required for the spindle checkpoint [PDF]
Christoph Baumann
openalex +1 more source
Magnifying Glass on Sinonasal NUT Carcinoma Heterogeneity via Spatial Transcriptomics
ABSTRACT Background Nuclear protein in testis (NUT) carcinomas (NCs) are rare, clinically aggressive tumors with characteristic translocation involving NUTM1 and BRD4 genes. While NCs are generally characterized by undifferentiated basaloid cells with focal/abrupt squamous differentiation, tumoral heterogeneity remains unexplored.
Diana Bell +8 more
wiley +1 more source
Analysis of a Mad2 homolog in Trypanosoma brucei provides possible hints on the origin of the spindle checkpoint [PDF]
Bungo Akiyoshi
openalex +1 more source
Cellular Angiofibroma of the Prostate
ABSTRACT Introduction Cellular angiofibroma is a rare, benign mesenchymal tumor that affects middle‐aged adults. It most frequently arises in the vulvovaginal or inguinoscrotal region. It is characterized by a slow clinical progression with no known potential for recurrence or metastasis.
Fien Janssens +4 more
wiley +1 more source
Condensin II is required for efficient Spindle Assembly Checkpoint activation in Drosophila male meiosis [PDF]
Cíntia Horta +2 more
openalex +1 more source
Competition between MPS1 and microtubules at kinetochores regulates spindle checkpoint signaling
Yoshitaka Hiruma +8 more
semanticscholar +1 more source
ABSTRACT Introduction Humoral hypercalcemia of malignancy (HCM) caused by parathyroid hormone–related peptide (PTHrP) is a common paraneoplastic syndrome, and renal cell carcinoma (RCC) is one of the main causes. However, initial presentation with rapidly progressive cognitive decline is rare.
Fumiakira Yano +6 more
wiley +1 more source
Overexpression of Fbxo6 inactivates spindle checkpoint by interacting with Mad2 and BubR1. [PDF]
Xu HZ +7 more
europepmc +1 more source
Melanoma: Pathogenesis and Targeted Therapy
The treatment landscape for advanced melanoma has evolved significantly. BRAF–MEK inhibitor combinations are standard for BRAF‐mutant melanoma, whereas targeting NRAS mutations is more challenging, with MEK inhibitors like tunlametinib emerging as an option.
Yang Fu +5 more
wiley +1 more source

