Results 201 to 210 of about 303,580 (303)
Spindle checkpoint activation by fungal orthologs of the S. cerevisiae Mps1 kinase. [PDF]
Fabritius A +4 more
europepmc +1 more source
Delineating the contribution of Spc105-bound PP1 to spindle checkpoint silencing and kinetochore microtubule attachment regulation. [PDF]
Roy B +4 more
europepmc +1 more source
Spatiotemporal Crosstalk Between Oocyte and the Microenvironment Governs Preovulatory Follicle Aging
Preovulatory follicle aging is characterized by two distinct phases—early oocyte protective and late degenerative phases. The degenerative phase involves a positive feedback loop between oocyte mitochondrial dysfunction mediated by a mitochondrial‐localized microprotein PIGBOS, and granulosa cell functional decline through a circular RNA circdlg1 ...
Xin Yi Koh +7 more
wiley +1 more source
The Bub1-TPR Domain Interacts Directly with Mad3 to Generate Robust Spindle Checkpoint Arrest. [PDF]
Leontiou I +9 more
europepmc +1 more source
In the course of TIS, cells undergo a profound epigenomic reorganization that underlies the development of a senescence‐associated phenotype and formation of an inflammatory microenvironment. ABSTRACT Cellular senescence is a fundamental biological process contributing to aging, often accompanied by extensive chromatin remodeling.
Ge Zhang +8 more
wiley +1 more source
Dual DNA–RNA panel with matched tumor–normal testing may improve diagnostic accuracy and inform treatment decisions in the routine clinical management of sarcoma. ABSTRACT Next‐generation sequencing‐based comprehensive cancer genomic profiling is promising in cancer management; however, most studies rely on tumor‐only DNA panels from single ...
Eiji Nakata +10 more
wiley +1 more source
The Prognostic Significance of Tumoral Melanosis
ABSTRACT Background Tumoral melanosis (TM) is a histological term to describe a nodular aggregation of macrophages containing melanin pigment (melanophages) that is devoid of viable melanocytes. It is most often identified in skin, where it may be appreciated clinically as a pigmented lesion; however, it can also be found in other organs such as lymph ...
Alison J. Potter +7 more
wiley +1 more source

