Spindle checkpoint - Open Access .click

Current Opinion in Cell Biology, 1996
The spindle assembly checkpoint monitors proper chromosome attachment to spindle microtubules and is conserved from yeast to humans. Checkpoint components reside on kinetochores of chromosomes and show changes in phosphorylation and localization as cells proceed through mitosis.
A D, Rudner, A W, Murray
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The Spindle Assembly and Spindle Position Checkpoints

Annual Review of Genetics, 2003
▪ Abstract The mitotic spindle segregates chromosomes to opposite ends of the cell in preparation for cell division. Chromosome attachment to the spindle is monitored by the spindle assembly checkpoint, and at least in yeast cells, penetration of one spindle pole into the bud is monitored by the spindle position checkpoint.
Daniel J, Lew, Daniel J, Burke
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Meiotic spindle, spindle checkpoint and embryonic aneuploidy

Frontiers in Bioscience, 2006
In mitosis, a spindle checkpoint plays important roles at the metaphase-anaphase transition to ensure the formation of a bipolar spindle, the completion of connecting chromosomes to microtubules and the alignment of all chromosomes at the spindle equator before initiation of anaphase.
Wei-Hua, Wang, Qing-Yuan, Sun
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The spindle checkpoint

Current Opinion in Genetics & Development, 1999
Prior to sister-chromatid separation, the spindle checkpoint inhibits cell-cycle progression in response to a signal generated by mitotic spindle damage or by chromosomes that have not attached to microtubules. Recent work has shown that the spindle checkpoint inhibits cell-cycle progression by direct binding of components of the spindle checkpoint ...
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mitosis
cell biology
cell division

cell cycle
cell
gene

kinetochore
chromosome
anaphase