Results 131 to 140 of about 110,511 (285)
Microtubule Dynamics and Oscillating State for Mitotic Spindle [PDF]
arXiv, 2010 We present a physical mechanism that can cause the mitotic spindle to oscillate. The driving force for this mechanism emerges from the polymerization of astral microtubules interacting with the cell cortex. We show that Brownian ratchet model for growing microtubules reaching the cell cortex, mediate an effective mass to the spindle body and therefore ...
arxiv
Influence of Cosolvents on the Pressure Stability of Human Serum Albumin
physica status solidi (a), EarlyView.Human serum albumin is able to bind various hydrophobic substances and drugs. To investigate this interaction, the protein structure is analyzed using small‐angle X‐ray scattering under high hydrostatic pressure. The resulting radius of gyration (see picture) indicates that hydrophobic substances influence the pressure stability of HSA differently ...
Jaqueline Savelkouls +3 more
wiley +1 more source
Biomarkers of cognitive impairment in obstructive sleep apnea
Sleep Research, EarlyView.Abstract Mild cognitive impairment (MCI) associated with obstructive sleep apnea (OSA) has garnered widespread attention. The mechanisms underlying MCI in patients with OSA are currently believed to be the combined effects of nocturnal intermittent hypoxia, hypercapnia, and sleep fragmentation, all of which can impact cerebral blood flow, synaptic ...
Zhijun Wang +7 more
wiley +1 more source
Small Structures, EarlyView.This article compares the mechanical properties of silkworm and spider silk by emphasizing their distinct hierarchical microstructures. Recent progress in multipathway engineering strategies that enhance silkworm silk's strength and elasticity is reviewed.
Mengqi Wang +13 more
wiley +1 more source
Self-organization of dynein motors generates meiotic nuclear oscillations.
PLoS Biology, 2009 Meiotic nuclear oscillations in the fission yeast Schizosaccharomyces pombe are crucial for proper chromosome pairing and recombination. We report a mechanism of these oscillations on the basis of collective behavior of dynein motors linking the cell ...
Sven K Vogel +4 more
doaj +1 more source
Dynein dynamics during meiotic nuclear oscillations of fission yeast [PDF]
, 2014 Cytoplasmic dynein is a ubiquitous minus-end directed motor protein that is essential for a variety of cellular processes ranging from cargo transport to spindle and chromosome positioning.
Ananthanarayanan, Vaishnavi
core +1 more source
Micrometer‐Sized Liposome‐Based Systems: A Hierarchical Breakdown
ChemSystemsChem, EarlyView.Micrometer‐sized liposomes (MSLs) are gaining attention for various applications, from biophysical cell models to molecular robots. Despite their growing importance, reviews on MSLs across disciplines are scarce. This review fills the gap by providing a systematic overview of MSL design, from applications to functionalization and to formation, aimed at
Shogo Hamada +9 more
wiley +1 more source
Quantifying Tubulin Concentration and Microtubule Number Throughout the Fission Yeast Cell Cycle
Biomolecules, 2019 The fission yeast Schizosaccharomyces pombe serves as a good genetic model organism for the molecular dissection of the microtubule (MT) cytoskeleton.
Isabelle Loiodice +8 more
doaj +1 more source
United European Gastroenterology Journal, EarlyView.ABSTRACT Background and Aims The long‐term outcomes of enteroscopic balloon dilation for small bowel strictures in patients with Crohn’s disease are not well understood. Although Crohn’s strictures can be classified into web‐like, ulcerated, and spindle‐shaped strictures based on endoscopic findings, the outcomes of enteroscopic balloon dilation ...
Sung Noh Hong +4 more
wiley +1 more source
A first-passage-time theory for search and capture of chromosomes by microtubules in mitosis [PDF]
Bulletin of Mathematical Biology 73(10):2483-506 (2011), 2009 The mitotic spindle is an important intermediate structure in eukaryotic cell division, in which each of a pair of duplicated chromosomes is attached through microtubules to centrosomal bodies located close to the two poles of the dividing cell. Several mechanisms are at work towards the formation of the spindle, one of which is the `capture' of ...
arxiv