Results 11 to 20 of about 31,479 (277)
Bud14 function is crucial for spindle pole body size maintenance. [PDF]
Turk J BiolSpindle pole bodies (SPB), the functional equivalent of centrosomes in yeast, duplicate through generation of a new SPB next to the old one. However, SPBs are dynamic structures that can grow and exchange, and mechanisms that regulate SPB size remain largely unknown.
Girgin SM, Çaydaşi AK.
europepmc +4 more sources
Current Biology, 2013 What is a spindle pole body? The spindle pole body (SPB) or duplication plaque of fungi is the functional equivalent of the centrosome in higher eukaryotes. SPBs serve as microtubule organizing centres (MTOCs), sites where microtubules (MTs) are assembled from tubulin subunits. In contrast to centrosomes, SPBs do not contain centrioles.
Christian Seybold, Santanu Mondal
openalex +3 more sources
Role of spindle pole body component 25 in neurodegeneration. [PDF]
Ann Transl Med, 2021 Aberrant growth and polarization of microglia are critical for pathological initiation and progression of neurodegenerative conditions like Alzheimer's disease (AD). However, the molecular signals that govern the outgrowth of microglia have not yet been fully determined.
Cui F, Xu Z, Lv Y, Hu J.
europepmc +4 more sources
Translational control of MPS1 links protein synthesis with the initiation of cell division and spindle pole body duplication in Saccharomyces cerevisiae. [PDF]
GeneticsBlank HM +6 more
europepmc +3 more sources
p53; separase (extra spindle pole bodies homolog 1; ESPL1) [PDF]
Science-Business eXchange, 2008 openalex +2 more sources
Fission yeast cells undergo nuclear division in the absence of spindle microtubules. [PDF]
PLoS Biology, 2010 Mitosis in eukaryotic cells employs spindle microtubules to drive accurate chromosome segregation at cell division. Cells lacking spindle microtubules arrest in mitosis due to a spindle checkpoint that delays mitotic progression until all chromosomes ...
Stefania Castagnetti +2 more
doaj +1 more source
Yeast Kinesin-5 Motor Protein CIN8 Promotes Accurate Chromosome Segregation
Cells, 2022 Accurate chromosome segregation depends on bipolar chromosome–microtubule attachment and tension generation on chromosomes. Incorrect chromosome attachment results in chromosome missegregation, which contributes to genome instability.
Delaney Sherwin +2 more
doaj +1 more source
Cosegregation of asymmetric features during cell division
Open Biology, 2021 Cellular asymmetry plays a major role in the ageing and evolution of multicellular organisms. However, it remains unknown how the cell distinguishes ‘old’ from ‘new’ and whether asymmetry is an attribute of highly specialized cells or a feature inherent ...
Silje Anda +3 more
doaj +1 more source
Cells, 2022 The spindle position checkpoint (SPOC) of budding yeast delays mitotic exit in response to misaligned spindles to ensure cell survival and the maintenance of genomic stability.
Yan Li, Kiwon Song
doaj +1 more source
Coordination of chromatid separation and spindle elongation by antagonistic activities of mitotic and S-phase CDKs. [PDF]
PLoS Genetics, 2013 Because cohesion prevents sister-chromatid separation and spindle elongation, cohesion dissolution may trigger these two events simultaneously. However, the relatively normal spindle elongation kinetics in yeast cohesin mutants indicates an additional ...
Fengshan Liang +2 more
doaj +1 more source