Results 41 to 50 of about 110,511 (285)
Disappearance of Cdc14 from the daughter spindle pole body requires Glc7-Bud14 [PDF]
İdil Kirdök, Ayşe Koca Çaydaşı
openalex +2 more sources
Abstract With the advancement of single‐cell separation techniques and high‐throughput sequencing platforms, single‐cell RNA‐sequencing (scRNA‐seq) has emerged as a vital technology for understanding tissue and organ systems at cellular resolution. Through transcriptional analysis, it is possible to characterize unique or rare cell types, interpret ...
Jordan H. Machlin, Ariella Shikanov
wiley +1 more source
Axin-1 Regulates Meiotic Spindle Organization in Mouse Oocytes. [PDF]
Axin-1, a negative regulator of Wnt signaling, is a versatile scaffold protein involved in centrosome separation and spindle assembly in mitosis, but its function in mammalian oogenesis remains unknown.
Xiao-Qin He+12 more
doaj +1 more source
Direct interaction between yeast spindle pole body components: Kar1p is required for Cdc31p localization to the spindle pole body. [PDF]
The Saccharomyces cerevisiae genes KAR1 and CDC31 are required for the initial stages of spindle pole body (SPB) duplication in yeast. The Cdc31 protein is most related to caltractin/centrin, a calcium-binding protein present in microtubule organizing centers in many organisms. Because of a variety of genetic interactions between CDC31 and KAR1 (Vallen,
Mark D. Rose, Sue Biggins
openaire +2 more sources
The effects of endocrine‐disrupting chemicals on ovarian‐ and ovulation‐related fertility outcomes
Abstract Exposure to endocrine‐disrupting chemicals (EDCs) is unavoidable, which represents a public health concern given the ability of EDCs to target the ovary. However, there is a large gap in the knowledge about the impact of EDCs on ovarian function, including the process of ovulation.
Katie L. Land+3 more
wiley +1 more source
The Organization of the Core Proteins of the Yeast Spindle Pole Body [PDF]
The spindle pole body (SPB) is the microtubule organizing center of Saccharomyces cerevisiae. Its core includes the proteins Spc42, Spc110 (kendrin/pericentrin ortholog), calmodulin (Cmd1), Spc29, and Cnm67. Each was tagged with CFP and YFP and their proximity to each other was determined by fluorescence resonance energy transfer (FRET).
Brian E. Snydsman+9 more
openaire +3 more sources
Leader of the SAC: molecular mechanisms of Mps1/TTK regulation in mitosis [PDF]
Discovered in 1991 in a screen for genes involved in spindle pole body duplication, the monopolar spindle 1 (Mps1) kinase has since claimed a central role in processes that ensure error-free chromosome segregation.
Spyridon T. Pachis+1 more
doaj +1 more source
$T^{1,1}$ truncation on the spindle [PDF]
We study the compactification of the $\mathcal{N}=2$ AdS$_5$ consistent truncation of the conifold, in presence of a Betti vector multiplet, on the spindle. We derive the BPS equations and solve them at the poles, computing the central charge for both the twist and the anti-twist class, turning on the magnetic charge associated to the baryonic symmetry.
arxiv +1 more source
The Cdc31p-binding protein Kar1p is a component of the half bridge of the yeast spindle pole body [PDF]
KAR1 has been identified as an essential gene which is involved in karyogamy of mating yeast cells and in spindle pole body duplication of mitotic cells (Rose, M. D., and G. R. Fink. 1987. Cell. 48:1047-1060).
Courtney, I.+4 more
core +2 more sources
The spindle position checkpoint (SPOC) is a spindle pole body (SPB, equivalent of mammalian centrosome) associated surveillance mechanism that halts mitotic exit upon spindle mis-orientation.
Yuliya Gryaznova+4 more
doaj +1 more source