Results 41 to 50 of about 110,511 (285)

Single‐cell RNA‐sequencing of retrieved human oocytes and eggs in clinical practice and for human ovarian cell atlasing

open access: yesMolecular Reproduction and Development, Volume 89, Issue 12, Page 597-607, December 2022., 2022
Abstract With the advancement of single‐cell separation techniques and high‐throughput sequencing platforms, single‐cell RNA‐sequencing (scRNA‐seq) has emerged as a vital technology for understanding tissue and organ systems at cellular resolution. Through transcriptional analysis, it is possible to characterize unique or rare cell types, interpret ...
Jordan H. Machlin, Ariella Shikanov
wiley   +1 more source

Axin-1 Regulates Meiotic Spindle Organization in Mouse Oocytes. [PDF]

open access: yesPLoS ONE, 2016
Axin-1, a negative regulator of Wnt signaling, is a versatile scaffold protein involved in centrosome separation and spindle assembly in mitosis, but its function in mammalian oogenesis remains unknown.
Xiao-Qin He   +12 more
doaj   +1 more source

Direct interaction between yeast spindle pole body components: Kar1p is required for Cdc31p localization to the spindle pole body. [PDF]

open access: yesThe Journal of cell biology, 1994
The Saccharomyces cerevisiae genes KAR1 and CDC31 are required for the initial stages of spindle pole body (SPB) duplication in yeast. The Cdc31 protein is most related to caltractin/centrin, a calcium-binding protein present in microtubule organizing centers in many organisms. Because of a variety of genetic interactions between CDC31 and KAR1 (Vallen,
Mark D. Rose, Sue Biggins
openaire   +2 more sources

The effects of endocrine‐disrupting chemicals on ovarian‐ and ovulation‐related fertility outcomes

open access: yesMolecular Reproduction and Development, Volume 89, Issue 12, Page 608-631, December 2022., 2022
Abstract Exposure to endocrine‐disrupting chemicals (EDCs) is unavoidable, which represents a public health concern given the ability of EDCs to target the ovary. However, there is a large gap in the knowledge about the impact of EDCs on ovarian function, including the process of ovulation.
Katie L. Land   +3 more
wiley   +1 more source

The Organization of the Core Proteins of the Yeast Spindle Pole Body [PDF]

open access: yesMolecular Biology of the Cell, 2005
The spindle pole body (SPB) is the microtubule organizing center of Saccharomyces cerevisiae. Its core includes the proteins Spc42, Spc110 (kendrin/pericentrin ortholog), calmodulin (Cmd1), Spc29, and Cnm67. Each was tagged with CFP and YFP and their proximity to each other was determined by fluorescence resonance energy transfer (FRET).
Brian E. Snydsman   +9 more
openaire   +3 more sources

Leader of the SAC: molecular mechanisms of Mps1/TTK regulation in mitosis [PDF]

open access: yesOpen Biology, 2018
Discovered in 1991 in a screen for genes involved in spindle pole body duplication, the monopolar spindle 1 (Mps1) kinase has since claimed a central role in processes that ensure error-free chromosome segregation.
Spyridon T. Pachis   +1 more
doaj   +1 more source

$T^{1,1}$ truncation on the spindle [PDF]

open access: yes, 2023
We study the compactification of the $\mathcal{N}=2$ AdS$_5$ consistent truncation of the conifold, in presence of a Betti vector multiplet, on the spindle. We derive the BPS equations and solve them at the poles, computing the central charge for both the twist and the anti-twist class, turning on the magnetic charge associated to the baryonic symmetry.
arxiv   +1 more source

The Cdc31p-binding protein Kar1p is a component of the half bridge of the yeast spindle pole body [PDF]

open access: yes, 1995
KAR1 has been identified as an essential gene which is involved in karyogamy of mating yeast cells and in spindle pole body duplication of mitotic cells (Rose, M. D., and G. R. Fink. 1987. Cell. 48:1047-1060).
Courtney, I.   +4 more
core   +2 more sources

A FRET-based study reveals site-specific regulation of spindle position checkpoint proteins at yeast centrosomes

open access: yeseLife, 2016
The spindle position checkpoint (SPOC) is a spindle pole body (SPB, equivalent of mammalian centrosome) associated surveillance mechanism that halts mitotic exit upon spindle mis-orientation.
Yuliya Gryaznova   +4 more
doaj   +1 more source

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