Activation of ADF/cofilin by phosphorylation-regulated Slingshot phosphatase is required for the meiotic spindle assembly in Xenopus laevis oocytes [PDF]
, 2013 We identify Xenopus ADF/cofilin (XAC) and its activator, Slingshot phosphatase (XSSH), as key regulators of actin dynamics essential for spindle microtubule assembly during Xenopus oocyte maturation.
Abe, Hiroshi +9 more
core +1 more source
Influence of Elastomer Layers in the Quality of Aluminum Parts on Finishing Operations [PDF]
, 2020 In finishing processes, the quality of aluminum parts is mostly influenced by static and dynamic phenomena. Different solutions have been studied toward a stable milling process attainment.
Lamikiz, Aitzol +3 more
core +2 more sources
Theoretical investigation on nonlinear dynamic characteristic of spindle system
Advanced Composites Letters, 2020 Radial gap will occur at the spindle–tool holder interface when the spindle rotates at high speed. Therefore, the radial gap will lead to the nonlinear stiffness at the spindle–tool holder connection, and it will have effects on dynamic characteristic of
Xiangsheng Gao +4 more
doaj +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Estimating temperature distribution and heat quantity of spindle shaft for machining centers
Journal of Advanced Mechanical Design, Systems, and ManufacturingThe thermal issue of spindles for machining centers is still fundamentally unresolved. Thermal problems due to increased temperature of the spindle shaft lead to thermal displacement of the tool axis and an increase in friction torque, consequently ...
Shingo KAJIKAWA +3 more
doaj +1 more source
Skin friction coefficient on a yarn package surface in ring spinning
, 2004 The skin friction coefficient on the surface of a rotating yarn package affects the power required to drive the package. This paper examines the relationship between the skin friction coefficient on the package surface and its diameter and rotating speed,
Barrie Fraser +3 more
core +1 more source
The application of ANFIS prediction models for thermal error compensation on CNC machine tools [PDF]
, 2014 Thermal errors can have significant effects on CNC machine tool accuracy. The errors come from thermal deformations of the machine elements caused by heat sources within the machine structure or from ambient temperature change.
Abdulshahed +35 more
core +1 more source
Molecular Oncology, EarlyView.A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath +13 more
wiley +1 more source
Shock and Vibration, 2016 The dynamic performance of a new high-speed spindle supported by water-lubricated hybrid bearings is experimentally studied on a test rig. The present design allows the speed of the spindle up to 30,000 rpm, with a bearing internal diameter of 40 mm ...
Lin Wang, Hua Xu
doaj +1 more source
Selection of design and operational parameters in spindle-holder-tool assemblies for maximum chatter stability by using a new analytical model [PDF]
, 2007 In this paper, using the analytical model developed by the authors, the effects of certain system design and operational parameters on the tool point FRF, thus on the chatter stability are studied.
Budak, Erhan +4 more
core +1 more source