Results 51 to 60 of about 93,060 (311)
Molecular Oncology, EarlyView.This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker +16 more
wiley +1 more source
Measurement Research of Motorized Spindle Dynamic Stiffness under High Speed Rotating
Shock and Vibration, 2015 High speed motorized spindle has become a key functional unit of high speed machine tools and effectively promotes the development of machine tool technology.
Xiaopeng Wang, Yuzhu Guo, Tianning Chen
doaj +1 more source
Research on dynamic characteristics of motorized spindle based on comprehensive stiffness of angular contact ball bearing [PDF]
Mechanical SciencesIn order to study the dynamic performance of a motorized spindle system more accurately and to consider the centrifugal effect, thermal effect of the angular contact ball bearing (ACBB) caused by high speed and influence of temperature rise on the ...
B. Dong, C. Lei, K. Liu, R. Song, P. Cui
doaj +1 more source
Multi-agent framework based on smart sensors/actuators for machine tools control and monitoring [PDF]
, 2006 Throughout the history, the evolutions of the requirements for manufacturing equipments have depended on the changes in the customers' demands. Among the present trends in the requirements for new manufacturing equipments, there are more flexible and ...
Archimède, Bernard, Desforges, Xavier
core +3 more sources
RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
Modeling Method Analysis of the Friction Torque for High Speed Spindle Bearing
MATEC Web of Conferences, 2018 The friction torque inside the high-speed spindle bearing determines the performance of the friction, wear, heat, temperature rise and life of the bearing.
Li Songsheng +4 more
doaj +1 more source
Measurement Science Review, 2019 The spindle vibrations of the high-speed grinding motorized spindle largely determine the machining quality and precision. In order to accurately predict the spindle vibrations of the PMSM high-speed grinding motorized spindle, the vibration causes are ...
Cheng Mingke, Gao Feng, Li Yan
doaj +1 more source
Gazi Üniversitesi Fen Bilimleri Dergisi, 2022 The aim of this work is to investigate the effect of the spindle speed and feed rate used in milling X153CrMoV12 cold work steel by X5070 blue coated solid carbide end mill on surface roughness and hardness of the workpiece.
Ferhat CERİTBİNMEZ, Erdoğan KANCA
doaj +1 more source
Thermal Model of High-Speed Spindle Units
Intelligent Information Management, 2010 For the purpose to facilitate development of high-speed Spindle Units (SUs) running on rolling bearings, we have developed a beam element model, algorithms, and software for computer analysis of thermal characteristics of SUs. The thermal model incorporates a model of heat generation in rolling bearings, a model of heat transfer from bearings, and ...
Jeong-Du Kim, Igor Zverv, Keon-Beom Lee
openaire +2 more sources
Advanced Functional Materials, EarlyView.A microphysiological lung fibrosis model recapitulates myofibroblast–vascular interactions. Induced myofibroblasts and patient‐derived IPF fibroblasts impair angiogenesis and increase vascular permeability via TGF‐β1–driven signaling. Pharmacological interventions with SB 431542 and VEGF supplementation restore vascular morphology and barrier function.
Elena Cambria +7 more
wiley +1 more source