Results 41 to 50 of about 107,650 (257)

Gene therapy genetic aspects and possibilities for degenerative diseases of intervertebral disks treatment

open access: yesUkrainian Neurosurgical Journal, 2008
At the beginning of 90th past century, due to intensive development of molecular biology and tissue engineering, knowledge accumulation about growth factors influence on the intervertebral disc cells, became possible.
E. G. Pedachenko, K. I. Horbatyuk
doaj   +1 more source

Microgastrinae (Hymenoptera: Braconidae) parasitizing Epirrita autumnata (Lepidoptera: Geometridae) larvae in Fennoscandia with description of Cotesia autumnatae Shaw, sp. n. [PDF]

open access: yes, 2013
The microgastrine subset of hymenopteran parasitoids of the geometrid Epirrita autumnata is investigated in Fennoscandia. Ecology, including population dynamics, of the moth has been intensively studied in northern and mountainous Finland, Norway and ...
Klemola, T   +6 more
core   +2 more sources

Differential Tiam1/Rac1 activation in hippocampal and cortical neurons mediates differential spine shrinkage in response to oxygen/glucose deprivation. [PDF]

open access: yes, 2014
Distinct neuronal populations show differential sensitivity to global ischemia, with hippocampal CA1 neurons showing greater vulnerability compared to cortical neurons.
Blanco Suarez, Elena   +4 more
core   +2 more sources

In silico engineering and simulation of RNA interferences nanoplatforms for osteoporosis treating and bone healing promoting

open access: yesScientific Reports, 2023
Osteoporosis is a bone condition characterized by reduced bone mineral density (BMD), poor bone microarchitecture/mineralization, and/or diminished bone strength.
Aylar Imanpour   +6 more
doaj   +1 more source

Inhibition by small-molecule ligands of formation of amyloid fibrils of an immunoglobulin light chain variable domain. [PDF]

open access: yes, 2015
Overproduction of immunoglobulin light chains leads to systemic amyloidosis, a lethal disease characterized by the formation of amyloid fibrils in patients' tissues. Excess light chains are in equilibrium between dimers and less stable monomers which can
Brumshtein, Boris   +7 more
core   +1 more source

Hematopoietic (stem) cells—The elixir of life?

open access: yesFEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo   +4 more
wiley   +1 more source

Low back pain and osteoarthritis pain: a perspective of estrogen

open access: yesBone Research, 2023
Low back pain (LBP) is the world’s leading cause of disability and is increasing in prevalence more rapidly than any other pain condition. Intervertebral disc (IVD) degeneration and facet joint osteoarthritis (FJOA) are two common causes of LBP, and both
Huiwen Pang   +6 more
doaj   +1 more source

Peripheral and central mechanisms involved in hormonal control of male and female reproduction [PDF]

open access: yes, 2016
Reproduction involves the integration of hormonal signals acting across multiple systems togenerate a synchronized physiological output. A critical component of reproduction is the luteinizinghormone (LH) surge, which is mediated by estradiol (E2) and ...
Bentley, G. E.   +6 more
core   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

MicroRNA-9 controls dendritic development by targeting REST [PDF]

open access: yes, 2014
MicroRNAs (miRNAs) are conserved noncoding RNAs that function as posttranscriptional regulators of gene expression. miR-9 is one of the most abundant miRNAs in the brain.
Akerblom   +95 more
core   +1 more source

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