Results 51 to 60 of about 138,981 (311)
Sonic hedgehog signaling in astrocytes mediates cell type-specific synaptic organization
eLife, 2019 Astrocytes have emerged as integral partners with neurons in regulating synapse formation and function, but the mechanisms that mediate these interactions are not well understood.
Steven A Hill +7 more
doaj +1 more source
Intracellular A53T Mutant α-Synuclein Impairs Adult Hippocampal Newborn Neuron Integration
Frontiers in Cell and Developmental Biology, 2020 Dendritic dysfunction is an early event in α-synuclein (α-syn) mediated neurodegeneration. Altered postsynaptic potential and loss of dendritic spines have been observed in different in vitro and in vivo models of synucleinopathies.
Martin Regensburger +9 more
doaj +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Journal of General and Family Medicine, 2018 The spine is homogeneously osteosclerotic and which appears to have no particular abnormal findings, however, that was proved to be a result of multiple metastases from prostate cancer. We should consider the possibility of prostate cancer if we see a "bright spine" on X-ray examination.
Ogushi, Akihiko +2 more
openaire +2 more sources
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
, 2020 This dataset contains detection limits for chemical data from fossil chaetognath spines (Phakelodus) and conodonts (Cordylodus, Palmatolepis, Neospathodus) measured using an electron ...
Wierzbowski, Hubert +2 more
core +1 more source
Zoologia (Curitiba), 2015 The cuticle is the outermost of the three cellular layers of the mammalian hair. It comprises numerous keratinized scales, whose morphology, combined with other microscopic characteristics of the hair, confers characteristic signature traits to various ...
Tarcísio de Souza Duarte, Gisele Lessa
doaj +1 more source
Conspicuous carotenoid-based pelvic spine ornament in three-spined stickleback populations—occurrence and inheritance [PDF]
PeerJ, 2015 Reports on reddish carotenoid-based ornaments in female three-spined sticklebacks (Gasterosteus aculeatus) are few, despite the large interest in the species’ behaviour, ornamentation, morphology and evolution.
CR Amundsen +4 more
doaj +2 more sources
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
The actin-modulating protein synaptopodin mediates long-term survival of dendritic spines
eLife, 2020 Large spines are stable and important for memory trace formation. The majority of large spines also contains synaptopodin (SP), an actin-modulating and plasticity-related protein.
Kenrick Yap +7 more
doaj +1 more source