Results 71 to 80 of about 138,981 (311)

Fine structure of synapses on dendritic spines [PDF]

, 2014
Camillo Golgi’s Reazione Nera led to the discovery of dendritic spines, small appendages originating from dendritic shafts. With the advent of electron microscopy (EM) they were identified as sites of synaptic contact.
Daniel eStuder, Graber, Werner Adrian, Graber, Werner, Xuejun Chai, Xuejun eChai, Frotscher, Michael, Nestel, Sigrun, Werner eGraber, Chai, Xuejun, Zhao, Shanting, Werner Graber, Michael Frotscher, Michael eFrotscher, Shanting Zhao, Sigrun eNestel, Shanting eZhao, Sigrun Nestel, Daniel Studer, Studer, Daniel Franz, Studer, Daniel   +19 more
core   +2 more sources

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Effects of Light Wavelength on Daughter Cladode Growth and Quality in Edible Cactus Nopalea cochenillifera Cultured in a Plant Factory with Artificial Light

Journal of Horticultural Research, 2018
In this study, we investigated the effects of different-colored light-emitting diodes (LEDs) on the growth and quality of daughter cladodes of the edible cactus Nopalea cochenillifera.
Horibe Takanori, Imai Shousei, Matsuoka Takuya   +2 more
doaj   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Sex differences in anxiety and depression: insights from adult rodent models of chronic stress and neural plasticity

Frontiers in Behavioral Neuroscience
The often co-morbid conditions of depression and anxiety are the most common mental illnesses and are more prevalent among females than males. Chronic stress paradigms in rodents serve as valuable preclinical models for investigating the factors ...
Rachel Bowman, Maya Frankfurt, Maya Frankfurt, Victoria Luine, Victoria Luine   +4 more
doaj   +1 more source

Subependymoma of the spine

Neurosciences, 2010
Subependymoma is a rare benign CNS tumor (WHO grade I). The common sites of origin for this type of tumor are the lateral and the fourth ventricles. A spinal intramedullary location is rare. Radiological features of intramedullary subependymoma can mimic more common and more aggressive tumor types.
Hussam E, Jabri, Mohammad A, Dababo, Ahmed M, Alkhani   +2 more
openaire   +2 more sources

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source

Unravelling Chemical Composition of Agave Spines: News from Agave fourcroydes Lem.

Plants, 2020
Spines are key plant modifications developed to deal against herbivores; however, its physical structure and chemical composition have been little explored in plant species.
Dalia C. Morán-Velázquez, Juan L. Monribot-Villanueva, Matthieu Bourdon, John Z. Tang, Itzel López-Rosas, Luis F. Maceda-López, José L. Villalpando-Aguilar, Lorena Rodríguez-López, Adrien Gauthier, Laura Trejo, Parastoo Azadi, Francisco Vilaplana, José A. Guerrero-Analco, Fulgencio Alatorre-Cobos   +13 more
doaj   +1 more source

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

FEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta, Nidhi Yadav, Subhasmita Das, R. Rajendra Kumar Reddy, Nupur Sharma, Amol Ratnakar Suryawanshi, Jaswinder Singh Maras, Ranjan Kumar Nanda   +7 more
wiley   +1 more source