Results 61 to 70 of about 77,711 (269)

The spiny relationship between parallel fibers, climbing fibers, and Purkinje cells

open access: yesFrontiers in Physiology
Cerebellar Purkinje cells are one of the most complex neurons in the central nervous system and are well known for their extensive dendritic tree dotted by dendritic spines.
Stefano Masoli   +4 more
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

open access: yesFEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill   +6 more
wiley   +1 more source

Estructura de tallas y edad del marlin rayado Tetrapturus audax (Pisces:Xiphidae),en Cabo San Lucas,Baja California Sur,México

open access: yesRevista de Biología Tropical, 2004
De 1988 a 1993 se muestrearon 1030 ejemplares de marlin rayado (Tetrapturus audax )capturados por la flota deportiva de Cabo San Lucas.Se recolectaron 389 espinas dorsales para la estimación de la edad.La relación Longitud mandibular-Radio total de la ...
Felipe Neri Melo Barrera   +1 more
doaj  

Internal Armature of the Hindgut of Pericapritermes nitobei (Shiraki)

open access: yesSociobiology, 2016
The internal armature of the hindgut of Pericapritermes nitobei was examined under a light microscope. Termites were obtained from Iriomote Island, Okinawa Prefecture, Japan, identified based on the typological characters of soldiers and 12S ...
Natsumi Kanzaki, Wakako Ohmura
doaj   +1 more source

Subependymoma of the spine

open access: yesNeurosciences, 2010
Subependymoma is a rare benign CNS tumor (WHO grade I). The common sites of origin for this type of tumor are the lateral and the fourth ventricles. A spinal intramedullary location is rare. Radiological features of intramedullary subependymoma can mimic more common and more aggressive tumor types.
Hussam E, Jabri   +2 more
openaire   +2 more sources

Protocol for quantifying miRNA trafficking across the endosomal membrane

open access: yesFEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh   +2 more
wiley   +1 more source

Two new species of Echinostoma (Digenea: Echinostomatidae) from Argentinean birds

open access: yesRevista Mexicana de Biodiversidad, 2018
Two new species of Echinostoma from Argentinean birds are described, illustrated and compared with morphologically close species. Echinostoma guirae n. sp. found parasitizing the intestine of Guira guira (Cuculidae) from Formosa Province is characterized
Lía I. Lunaschi   +2 more
doaj   +1 more source

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

open access: yesFEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia   +9 more
wiley   +1 more source

Circadian clock regulates the shape and content of dendritic spines in mouse barrel cortex.

open access: yesPLoS ONE, 2019
Circadian rhythmicity affects neuronal activity induced changes in the density of synaptic contacts and dendritic spines, the most common location of synapses, in mouse somatosensory cortex.
Malgorzata Jasinska   +5 more
doaj   +1 more source

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