Results 51 to 60 of about 457,484 (165)

Dynamic Global and Local Enhancement of Theta‐Band Functional Networks as Neural Markers of Spinal Cord Stimulation Efficacy in Disorders of Consciousness

open access: yesCNS Neuroscience &Therapeutics, Volume 32, Issue 9, September 2026.
To address the critical challenge of lacking objective prognostic neural markers for evaluating long‐term efficacy of spinal cord stimulation (SCS) in disorders of consciousness (DoC), this study proposed an EEG‐based dynamic functional connectivity (dFC) framework, uncovering SCS‐induced transient neural reorganization through higher‐order feature ...
Yinuo Liu   +6 more
wiley   +1 more source

How mainly spinothalamic tract cells are there? A retrograde tracing study in cat

open access: yes, 2004
The spinothalamic tract, well known for its role in nociception, is the most frequently studied ascending pathway originating from the spinal cord. It is known that spinothalamic neurons are located in all segments of the spinal cord, but in most mammals
Holstege, G, Mouton, LJ, Klop, EM
core   +1 more source

The Prevalence of Neuropathic Pain in Multiple Sclerosis—A Systematic Review and Meta‐Analysis Using the NeuPSIG Algorithm

open access: yesEuropean Journal of Pain, Volume 30, Issue 8, September 2026.
ABSTRACT Background and Objectives Multiple sclerosis (MS) is a neurodegenerative disorder frequently leading to neuropathic pain. Due to the neurodegenerative nature, the diagnosis of neuropathic pain remains challenging. A grading system has been developed providing an overview of diagnostic certainty (i.e., possible, probable and definite). Since no
Rasmus C. Jungersen   +4 more
wiley   +1 more source

Rostrocaudal and laminar distribution of spinothalamic neurons in the high cervical spinal cord of the cat

open access: yes, 1981
In the cat, retrogradely labelled spinothalamic tract cells were found in contralateral medial laminae VI and lateral laminae VII-VIII and ipsilateral lateral laminae VII-VIII and medial laminae VI of the C1, C2, C3 and C4 segments.
Snow P.J., Comans P.E.
core   +1 more source

Beyond motor recovery: Stem cell‐derived exosomes for sensory restoration and neuropathic pain relief after spinal cord injury

open access: yesIbrain, Volume 12, Issue 3, Page 330-349, Fall 2026.
Stem cell‐derived exosomes offer a promising cell‐free therapy for spinal cord injury by delivering diverse bioactive cargos. This review highlights their roles in motor recovery, sensory restoration, and neuropathic pain relief through axonal regeneration, synaptic remodeling, neural differentiation, glial metabolic reprogramming, immunomodulation ...
Md Miftahul Mithu   +8 more
wiley   +1 more source

Brainstem fiber tracts and manual ROI placement.

open access: yes, 2020
Placement of ROI-pairs (“Seed” and “target”) and their fiber outputs performed with manual tractography. Abbreviations: MLF = medial longitudinal fasciculus; DLF = dorsal longitudinal fasciculus; SCP = superior cerebellar peduncle; MFT = medial forebrain
Ansgar J. Furst (3692116)   +8 more
core   +1 more source

Cervical Atrophy Following Complete Thoracic Spinal Cord Injury: Insights From a Multinational Cohort

open access: yesEuropean Journal of Neurology, Volume 33, Issue 9, September 2026.
Thoracic spinal cord injury is associated with significant remote degeneration of the uninjured cervical cord, even in the absence of direct cervical damage. Compared to able‐bodied controls, individuals with chronic thoracic injury showed reduced cervical cross‐sectional area and antero‐posterior/right–left diameters, along with increased eccentricity
Yann Quidé   +8 more
wiley   +1 more source

Excitation of primate spinothalamic neurons by cutaneous C-fiber volleys

open access: yes, 1979
1. The responses of spinothalamic tract cells in the lumbosacral spinal cords of anesthetized monkeys were examined following electrical stimulation of the sural nerve or the application of noxious thermal and mechanical stimuli to the skin on the ...
K. D. Gerhart   +3 more
core   +1 more source

Spinothalamic tract neurons in laminae I, III and IV of the rat: a retrograde neuronal tracing study [PDF]

open access: yes, 2009
Ascending pathways in the spinal cord are very important in transmitting sensory information from the periphery to the higher brain centres. The spinothalamic tract represents an important component of these ascending pathways, and it has been ...
Al-Khater, Khulood
core   +4 more sources

Successful pain control with add-on methadone for refractory neuropathic pain due to radiation necrosis in pontine metastatic lesion: a case report

open access: yesBMC Palliative Care
Background Central pain, characterized by neuropathic pain, can manifest due to injury to the superior spinothalamic tract. The brainstem includes sensory and motor pathways as well as nuclei of the cranial nerves, and therefore cancer metastasis in the ...
Fumio Kurosaki   +6 more
doaj   +1 more source

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