Results 81 to 90 of about 4,814 (215)
Discrimination and Quantification of Glomerular Receptor Subtypes for Atrial Natriuretic Factor (Anf) [PDF]
Binding sites for atrial natriuretic factor (ANF) were determined on isolated rat glomeruli as well as on glomerular membranes. To define optimal conditions, binding of ANF was investigated varying incubation time, temperature and protein concentration ...
Gerbes, Alexander L. +2 more
core +1 more source
The structural equation model of the relationships between rejectionsensitivity (RS) and anxious‐depressive attack (ADA). RS contributes significantly to the onset of ADA. Abstract This paper aimed to find clues to treatment‐resistant depression (TRD) solutions.
Hisanobu Kaiya
wiley +1 more source
Alcohol-related expectancies are associated with the D2 dopamine receptor and GABAa receptor B3 subunit genes [PDF]
Molecular genetic research has identified promising markers of alcohol dependence, including alleles of the D2 dopamine receptor (DRD2) and the GABAA receptor ¬3 subunit (GABRB3) genes.
Bandura +87 more
core +2 more sources
Chronic haloperidol impacts fear memory differently than single doses. Our study unveils how chronic D2R antagonist treatment alters fear memory expression and extinction in rats, offering crucial insights into potential therapeutic approaches for fear memory disorders.
Kosuke Enomoto +7 more
wiley +1 more source
Ligand-Gated Chloride Channels Are Receptors for Biogenic Amines in C. elegans [PDF]
Biogenic amines such as serotonin and dopamine are intercellular signaling molecules that function widely as neurotransmitters and neuromodulators. We have identified in the nematode Caenorhabditis elegans three ligand-gated chloride channels that are ...
Abe, Namiko +2 more
core +2 more sources
Fluorescent Tools for the Imaging of Dopamine D2‐Like Receptors**
In this study, we have identified UR‐MN212 (20), a spiperone‐based fluorescent ligand bearing a 5‐TAMRA dye, as suitable for fluorescence microscopy at the D2R. The binding affinity in the single‐digit nanomolar range could be determined in radioligand competition binding and molecular brightness studies at D2‐like receptors.
Martin Nagl +11 more
wiley +1 more source
Elevated Cholesterol in the Coxiella burnetii Intracellular Niche Is Bacteriolytic [PDF]
Coxiella burnetii is an intracellular bacterial pathogen and a significant cause of culture-negative endocarditis in the United States. Upon infection, the nascent Coxiella phagosome fuses with the host endocytic pathway to form a large lysosome-like ...
Barbara Burleigh +5 more
core +2 more sources
The freshwater crab Aegla platensis was used as a model to induce ovarian growth by adding different neuroregulators to a pellet food formulation. Added compounds were the dopaminergic inhibitor spiperone or the enkephalinergic inhibitor naloxone, both ...
Alejandra V Cahansky +5 more
doaj
Genome-wide shRNA screen revealed integrated mitogenic signaling between dopamine receptor D2 (DRD2) and epidermal growth factor receptor (EGFR) in glioblastoma [PDF]
Glioblastoma remains one of the deadliest of human cancers, with most patients succumbing to the disease within two years of diagnosis. The available data suggest that simultaneous inactivation of critical nodes within the glioblastoma molecular ...
Akers, Johnny C. +15 more
core +2 more sources
The transport of compounds around the body has been a topic of interest for many years, and the advent of non-invasive biological imaging in living tissue has made huge advances in the characterisation and localisation of cellular receptors for use in ...
Casey, Duncan Robert +1 more
core +1 more source

