Results 81 to 90 of about 4,814 (215)

Discrimination and Quantification of Glomerular Receptor Subtypes for Atrial Natriuretic Factor (Anf) [PDF]

, 1991
Binding sites for atrial natriuretic factor (ANF) were determined on isolated rat glomeruli as well as on glomerular membranes. To define optimal conditions, binding of ANF was investigated varying incubation time, temperature and protein concentration ...
Gerbes, Alexander L., Kollenda, Margit C., Scarborough, Robert M.   +2 more
core   +1 more source

Anxious‐depressive attack and rejection sensitivity—Toward a new approach to treatment‐resistant depression

Neuropsychopharmacology Reports, Volume 44, Issue 1, Page 17-28, March 2024.
The structural equation model of the relationships between rejectionsensitivity (RS) and anxious‐depressive attack (ADA). RS contributes significantly to the onset of ADA. Abstract This paper aimed to find clues to treatment‐resistant depression (TRD) solutions.
Hisanobu Kaiya
wiley   +1 more source

Alcohol-related expectancies are associated with the D2 dopamine receptor and GABAa receptor B3 subunit genes [PDF]

, 2004
Molecular genetic research has identified promising markers of alcohol dependence, including alleles of the D2 dopamine receptor (DRD2) and the GABAA receptor ￢3 subunit (GABRB3) genes.
Bandura, Bandura, Bau, Berman, Berridge, Blomqvist, Blum, Bruce R Lawford, Christiansen, Cohen, Comings, Connor, Connor, David, Davies, Depue, DiChiara, DiChiara, DiChiara, DiChiara, Dimitrov, Duan, Dudek, Ernest P Noble, Feeney, Gelernter, Gerald F.X Feeney, Goldman, Grandy, Greenfield, Gurling, Hitzemann, Hollerman, Ikemoto, Jönsson, Kidd, Knight, Laruelle, Lawford, Lawford, Lawford, Lawford, Long, Luddens, Madrid, Maldonado, McCarthy, McCarthy, Miller, Monti, Mutirangura, Neiswanger, Noble, Noble, Noble, Noble, Noble, Noble, Noble, Noble, Noone, Ott, Pato, Persico, Pohjalainen, Robinson, Ross McD Young, Schultz, Schultz, Selzer, Silvestri, Spitz, Terry Ritchie, Thanos, Thompson, Uhl, Vernon, Vik, Volkow, Volkow, Wells-Parker, Williams, Wilson, Wise, Young, Young, Young, Young   +87 more
core   +2 more sources

Effects of chronic haloperidol treatment on the expression of fear memory and fear memory extinction in the cued fear‐conditioned rats

Neuropsychopharmacology Reports, Volume 44, Issue 1, Page 197-205, March 2024.
Chronic haloperidol impacts fear memory differently than single doses. Our study unveils how chronic D2R antagonist treatment alters fear memory expression and extinction in rats, offering crucial insights into potential therapeutic approaches for fear memory disorders.
Kosuke Enomoto, Kazuro Shibata, Hiroyuki Muraoka, Masahiko Kawano, Ken Inada, Jun Ishigooka, Katsuji Nishimura, Hidehiro Oshibuchi   +7 more
wiley   +1 more source

Ligand-Gated Chloride Channels Are Receptors for Biogenic Amines in C. elegans [PDF]

, 2008
Biogenic amines such as serotonin and dopamine are intercellular signaling molecules that function widely as neurotransmitters and neuromodulators. We have identified in the nematode Caenorhabditis elegans three ligand-gated chloride channels that are ...
Abe, Namiko, Horvitz, Howard Robert, Ringstad, Niels   +2 more
core   +2 more sources

Fluorescent Tools for the Imaging of Dopamine D2‐Like Receptors**

ChemBioChem, Volume 25, Issue 2, January 15, 2024.
In this study, we have identified UR‐MN212 (20), a spiperone‐based fluorescent ligand bearing a 5‐TAMRA dye, as suitable for fluorescence microscopy at the D2R. The binding affinity in the single‐digit nanomolar range could be determined in radioligand competition binding and molecular brightness studies at D2‐like receptors.
Martin Nagl, Denise Mönnich, Niklas Rosier, Hannes Schihada, Alexei Sirbu, Nergis Konar, Irene Reyes‐Resina, Gemma Navarro, Rafael Franco, Peter Kolb, Paolo Annibale, Steffen Pockes   +11 more
wiley   +1 more source

Elevated Cholesterol in the Coxiella burnetii Intracellular Niche Is Bacteriolytic [PDF]

, 2017
Coxiella burnetii is an intracellular bacterial pathogen and a significant cause of culture-negative endocarditis in the United States. Upon infection, the nascent Coxiella phagosome fuses with the host endocytic pathway to form a large lysosome-like ...
Barbara Burleigh, Dhritiman Samanta, Minal Mulye, Robert A. Heinzen, Seth Winfree, Stacey D. Gilk   +5 more
core   +2 more sources

Induction of ovarian growth in Aegla platensis (Crustacea, Aeglidae) by means of neuroregulators incorporated to food

Revista de Biología Tropical, 2008
The freshwater crab Aegla platensis was used as a model to induce ovarian growth by adding different neuroregulators to a pellet food formulation. Added compounds were the dopaminergic inhibitor spiperone or the enkephalinergic inhibitor naloxone, both ...
Alejandra V Cahansky, Bibiana Kaiser Dutra, Daniela da Silva Castiglioni, Guendalina Turcato Oliveira, Georgina Bond Buckup, Enrique M Rodríguez   +5 more
doaj  

Genome-wide shRNA screen revealed integrated mitogenic signaling between dopamine receptor D2 (DRD2) and epidermal growth factor receptor (EGFR) in glioblastoma [PDF]

, 2014
Glioblastoma remains one of the deadliest of human cancers, with most patients succumbing to the disease within two years of diagnosis. The available data suggest that simultaneous inactivation of critical nodes within the glioblastoma molecular ...
Akers, Johnny C., Carter, Bob S., Cavenee, Webster, Chen, Clark C., Elledge, Stephen, Furnari, Frank, Futalan, Diahnn, Kozono, David, Kushwaha, Deepa, Kwon, Chang-Hyuk, Li, Jie, Ng, Kimberly, Schlabach, Michael, Shen, Ying, Steed, Tyler, Zhu, Shan   +15 more
core   +2 more sources

Drug interactions with lipid membranes: the effects of drug and lipid structure upon rates of ester hydrolysis

, 2012
The transport of compounds around the body has been a topic of interest for many years, and the advent of non-invasive biological imaging in living tissue has made huge advances in the characterisation and localisation of cellular receptors for use in ...
Casey, Duncan Robert, Casey, Duncan Robert   +1 more
core   +1 more source