Results 131 to 140 of about 23,483 (241)
Modelling Growth, Remodelling and Damage of a Thick-walled Fibre-reinforced Artery with Active Response: Application to Cerebral Vasospasm and Treatment [PDF]
arXivCerebral vasospasm, a prolonged constriction of cerebral arteries, is the first cause of morbidity and mortality for patients who survive hospitalisation after aneurysmal subarachnoid haemorrhage. The recent finding that stent-retrievers can successfully treat the disease has challenged the viewpoint that damage to the extracellular matrix is necessary.
arxiv
The Kaohsiung Journal of Medical Sciences, EarlyView.ABSTRACT This study explores the differential expression of lncRNA PVT1 in intracranial aneurysms (IAs) and its role in the phenotypic switching of vascular smooth muscle cells (VSMCs). PVT1 and ALOX5 expressions in the serum of IA patients and healthy controls were detected by qRT‐PCR.
Yu‐Fei Cheng +4 more
wiley +1 more source
A computational study of the effects of remodelled electrophysiology and mechanics on initiation of ventricular fibrillation in human heart failure [PDF]
arXiv, 2014 The study of pathological cardiac conditions such as arrhythmias, a major cause of mortality in heart failure, is becoming increasingly informed by computational simulation, numerically modelling the governing equations. This can provide insight where experimental work is constrained by technical limitations and/or ethical issues.
arxiv
α‐Synuclein in Parkinson's Disease: From Bench to Bedside
Medicinal Research Reviews, Volume 45, Issue 3, Page 909-946, May 2025.ABSTRACT α‐Synuclein (α‐syn), a pathological hallmark of PD, is emerging as a bridging element at the crossroads between neuro/immune‐inflammatory responses and neurodegeneration in PD. Several evidence show that pathological α‐syn accumulates in neuronal and non‐neuronal cells (i.e., neurons, microglia, macrophages, skin cells, and intestinal cells ...
Gabriele Bellini +8 more
wiley +1 more source
Frontiers in Pharmacology, 2015 The onset of pregnancy implies the appearance of a new organ, the placenta. One main function of the placenta is to supply oxygen to the fetus via hemoproteins.
Maria Laura Zenclussen +6 more
doaj +1 more source
Medicinal Research Reviews, Volume 45, Issue 3, Page 842-866, May 2025.ABSTRACT At different stages of life, from embryonic to postnatal, varying oxygen concentrations modulate cellular gene expression by enhancing or repressing hypoxia‐inducible transcription factors. During embryonic/fetal life, these genes encode proteins involved in adapting to a low‐oxygen environment, including the induction of specific enzymes ...
Luca Filippi +9 more
wiley +1 more source
Assessment of Maternal Vascular Remodeling During Pregnancy in the Mouse Uterus. [PDF]
, 2015 The placenta mediates the exchange of factors such as gases and nutrients between mother and fetus and has specific demands for supply of blood from the maternal circulation.
Colucci, Francesco +2 more
core +2 more sources
Bisphenol A exposure during early pregnancy impairs uterine spiral artery remodeling and provokes intrauterine growth restriction in mice [PDF]
, 2018 Judith Elisabeth Müller +7 more
openalex +1 more source
Prediction of Preeclampsia in Twins Using First Trimester: cffDNA Fraction, PlGF, and MAP
Prenatal Diagnosis, EarlyView.ABSTRACT Objectives To evaluate cell‐free fetal DNA fraction (cffDNAF) as a first‐trimester screening marker for preeclampsia necessitating delivery before 37 weeks' gestation in twin pregnancies alone and combined with other bio‐markers. Methods Women with two live fetuses were enrolled in the first trimester, and evaluated for cffDNAF as a first ...
Ran Svirsky +9 more
wiley +1 more source