Results 151 to 160 of about 6,534 (210)

Bioresorbable Scaffolds for Coronary Arteries: Where Do We Stand Today?

open access: yesVIEW Medicine, Volume 1, Issue 1, August 2026.
Bioresorbable coronary scaffolds are moving from thick strut pitfalls to thinner, stronger, healing‐oriented designs. Integrating advances in materials, guided implantation with preparation, size, and postdilation steps, and resorption aligned to healing, we synthesize clinical evidence and chart a roadmap toward intelligent, transient platforms ...
Junya Matsuda   +5 more
wiley   +1 more source

Apiotrichum‐Centered Fungal Interaction Network Disturbance Correlates With Increased Arterial Stiffness

open access: yesAging Cell, Volume 25, Issue 8, August 2026.
Apiotrichum‐centered gut fungal network disturbance correlates with increased arterial stiffness. Five driver genera including Apiotrichum, Mycothermus, Flavocillium, Hyaloscypha, and Microscypha regulate the interaction shift. Thirty‐nine metabolites comprising organic acids, fatty acyls, and sucrose target vasoconstriction regulators CYP11B2, ROCK2 ...
Jiarui Chen   +9 more
wiley   +1 more source

Effects of Physical Activity on Brain White Matter Integrity Are Region‐, Dose‐, and Age‐Dependent: Findings From the Population‐Based Rhineland Study

open access: yesAging Cell, Volume 25, Issue 8, August 2026.
Physical activity is related to more aligned white matter fibers and microstructural reorganization of the brain. Body weight, cardiometabolic, and inflammatory factors could partly mediate the effects of physical activity on brain white matter microstructure. The effects of physical activity on the brain are age‐ and region‐specific.
Eva Saxler   +7 more
wiley   +1 more source

Altered Distribution of CD14+ Macrophages and Reduced ROS Activity in Preeclamptic Placentas

open access: yesAmerican Journal of Reproductive Immunology, Volume 96, Issue 2, August 2026.
ABSTRACT Problem Pregnancy requires a delicate balance between maternal immune tolerance and protective responses, with macrophages playing a pivotal role in placental development and immune regulation. Preeclampsia, a hypertensive disorder that affects 5%–8% of pregnancies, is associated with immune dysregulation, oxidative stress, and impaired ...
Luis Donis‐Maturano   +5 more
wiley   +1 more source

Placental basal plate with attached myofibers and adverse pregnancy outcomes: A systematic scoping review

open access: yesActa Obstetricia et Gynecologica Scandinavica, Volume 105, Issue 8, Page 1435-1444, August 2026.
The presence of basal plate myometrial fibers was associated with higher rates of placenta‐related pregnancy disorders and abnormal placental attachment in subsequent pregnancies, but heterogeneity in the data was found due to variable inclusion criteria, sampling methods, and reported outcomes.
Eric Jauniaux   +3 more
wiley   +1 more source

Pathophysiological and Molecular Features of DXd ADC‐Related Interstitial Pneumonitis in Cynomolgus Monkeys

open access: yesCancer Science, Volume 117, Issue 8, Page 2305-2316, August 2026.
An interstitial lung disease model for DXd antibody‐drug conjugates was established in cynomolgus monkeys by weekly dosing of a non‐targeting DXd ADC. Integrated analysis of bronchoalveolar lavage fluid–derived extracellular vesicle proteomics and lung single‐cell RNA sequencing reveals cell‐type‐resolved molecular features of DXd ADC‐related lung ...
Kazuyoshi Kumagai   +5 more
wiley   +1 more source

Unravelling the Significance of Cystatin C and Bunina Bodies in Amyotrophic Lateral Sclerosis Pathogenesis

open access: yesNeuropathology and Applied Neurobiology, Volume 52, Issue 4, August 2026.
ABSTRACT Amyotrophic lateral sclerosis (ALS), also known as motor neuron disease (MND), is a fatal neurodegenerative disease primarily affecting motor neurons. Two key protein inclusions found in lower motor neurons serve as neuropathological hallmarks of the disease in human tissue: the TDP43‐positive inclusion and the cystatin C‐positive Bunina body.
Sarah M. Granger   +5 more
wiley   +1 more source

Interplay between PNPLA3 genotype, liver steatosis, and cardiac remodeling in young adults: A magnetic resonance imaging study

open access: yesPhysiological Reports, Volume 14, Issue 15, August 2026.
The PNPLA3 rs738409 variant was associated with cardiac remodeling, manifested as greater left ventricular mass, left ventricular end‐diastolic volume and right ventricular end‐diastolic volume, among young adults with steatotic liver disease but not in those without steatotic liver disease.
Nick S. R. Lan   +9 more
wiley   +1 more source

Bisphenol A exposure during early pregnancy impairs uterine spiral artery remodeling and provokes intrauterine growth restriction in mice. [PDF]

open access: yesSci Rep, 2018
Müller JE   +7 more
europepmc   +1 more source

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