Results 131 to 140 of about 6,534 (210)

Erythropoietin Disequilibrium in Hypertensive Disorders of Pregnancy: Molecular Crosstalk, Placental Hypoxia and Perinatal Consequences

Comprehensive Physiology, Volume 16, Issue 4, August 2026.
Placental hypoxia, HIF‐1α activation, renal HIF‐2α‐mediated EPO signaling, inflammation, and hepcidin‐driven iron restriction converge to produce functional EPO resistance. This erythropoietin disequilibrium impairs effective erythropoiesis, aggravates maternal vascular dysfunction, compromises placental oxygen transfer, and contributes to adverse ...
Emmanuel Ifeanyi Obeagu
wiley   +1 more source

Thromboinflammatory biomarkers in obstetric pathophysiology: Predictive insights into placental insufficiency and feto‐maternal adverse outcomes

Clinical and Translational Discovery, Volume 6, Issue 4, August 2026.
Placental insufficiency is a thromboinflammatory disorder driven by angiogenic imbalance, complement activation, endothelial dysfunction and coagulation dysregulation, leading to microvascular thrombosis, impaired uteroplacental perfusion and adverse maternal and fetal outcomes, including pre‐eclampsia, fetal growth restriction and stillbirth. Abstract
Emmanuel Ifeanyi Obeagu
wiley   +1 more source

Krüppel-like factor 17 upregulates uterine corin expression and promotes spiral artery remodeling in pregnancy. [PDF]

Proc Natl Acad Sci U S A, 2020
Wang C, Wang Z, He M, Zhou T, Niu Y, Sun S, Li H, Zhang C, Zhang S, Liu M, Xu Y, Dong N, Wu Q.   +12 more
europepmc   +1 more source

Quantification of Tricuspid Valve Regurgitation With 2D and 4D‐Flow MRI: Comparison of Different Methods in Adult Patients With Ebstein's Anomaly

Journal of Magnetic Resonance Imaging, Volume 64, Issue 2, Page 515-523, August 2026.
ABSTRACT Background Ebstein's anomaly (EA) is a congenital heart disorder involving tricuspid valve dysplasia and right heart abnormalities resulting in severe tricuspid regurgitation (TR). Multiple techniques assess regurgitation severity, but their correlation with EA severity markers remains unclear. Purpose To compare MRI techniques for quantifying
Eric Buffle, Mathieu Albertini, Damian Craiem, Victor Waldmann, Francesca Pitocco, Laurence Iserin, Umit Gencer, Elie Mousseaux, Gilles Soulat   +8 more
wiley   +1 more source

Divergent Atrial Transcriptomic Signatures in Diabetic and Nondiabetic Atrial Fibrillation

Journal of Arrhythmia, Volume 42, Issue 4, August 2026.
Diabetes alters the atrial transcriptome in atrial fibrillation, characterized by enhanced mitochondrial ATP synthesis, suppressed immune and inflammatory pathways, and distinct miRNA expression profiles, suggesting metabolic and epigenetic remodeling of the atrial substrate.
Kenshi Yoshimura, Yuya Kiriake, Hiroki Osanai, Mengyan Wei, Shinichiro Kume, Tatsuki Kurokawa, Masaki Morishima, Ryusuke Suzuki, Shinji Miyamoto, Katsushige Ono   +9 more
wiley   +1 more source

Dynamic spiral artery remodeling in early human pregnancy: an analysis of specimens collected with a standardized protocol†. [PDF]

Biol Reprod
Ye S, Ma Y, Li W, Qi L, Fang X, Yu X, Yu D, Wang X, Chen DB, Wang YL.   +9 more
europepmc   +1 more source

Maternal systemic vascular dysfunction in a primate model of defective uterine spiral artery remodeling.

Am J Physiol Heart Circ Physiol, 2021
Albrecht ED, Babischkin JS, Aberdeen GW, Burch MG, Pepe GJ.   +4 more
europepmc   +1 more source

Pulsed Field Ablation Versus Thermal Ablation for First‐Time Pulmonary Vein Isolation in Atrial Fibrillation: A Systematic Review and Meta‐Analysis

Journal of Arrhythmia, Volume 42, Issue 4, August 2026.
In patients undergoing first‐time pulmonary vein isolation for atrial fibrillation, pulsed field ablation was associated with lower arrhythmia recurrence and reduced transient phrenic nerve palsy compared with thermal ablation. Durable pulmonary vein isolation and most safety outcomes were similar between treatment strategies.
Yousef Radwan Alnomani, Abdelaziz A. Awad, Ahmed Abdelaziz, Mazen Negmeldin Aly Yassin, Omnia Samy El‐Sayed, Menna Marwan, Alaa Radwan Mady, Mahmoud Ali, Khaled Akil, Belal Hamed, Al‐Hassan Soliman Wadan, Mohamed Abdelsalam   +11 more
wiley   +1 more source

Mechanosensing of Shear Stress and Uterine Spiral Artery Remodeling by Invasive Trophoblasts in Early Pregnancy. [PDF]

Int J Mol Sci
Szukiewicz D, Trojanowski S, Wróbel E, Wojdasiewicz P, Szewczyk G.   +4 more
europepmc   +1 more source

Fetal growth restriction is a host specific response to infection with an impaired spiral artery remodeling-inducing strain of Porphyromonas gingivalis. [PDF]

Sci Rep, 2020
Tavarna T, Phillips PL, Wu XJ, Reyes L.
europepmc   +1 more source