The Kaohsiung Journal of Medical Sciences, EarlyView.ABSTRACT Preeclampsia (PE) is an obstetric disease that is characterized by reduced migration and invasion of placental trophoblast cells. Here, the effects of the E3 ubiquitin ligase UBE3A on the migration and invasion of trophoblast cells were evaluated.
Xiu‐Jun Li +5 more
wiley +1 more source
Altered expression of norepinephrine transporter and norepinephrine in human placenta cause pre-eclampsia through regulated trophoblast invasion [PDF]
, 2013 Objective: We investigated the norepinephrine transporter (NET) expression in normal and pre-eclamptic placentas and analyzed the invasion activity of trophoblastic cells based on norepinephrine (NE)-NET regulation.
Choi, Jong Ho +4 more
core +1 more source
Magnetic Resonance in Medicine, EarlyView.ABSTRACT Purpose To develop accelerated 3D phase contrast (PC) MRI using jointly learned wave encoding and reconstruction. Methods Pseudo‐fully sampled neurovascular 4D flow data (N = 40) and a simulation framework were used to learn phase encoding locations, wave readout parameters, and model‐based reconstruction network (MoDL) for a rapid 3D PC scan (
Chenwei Tang +7 more
wiley +1 more source
A Surgical Perspective on Targeted Therapy of Hepatocellular Carcinoma. [PDF]
, 2015 Hepatocellular carcinoma (HCC), the second leading cause of cancer deaths worldwide, is difficult to treat and highly lethal. Since HCC is predominantly diagnosed in patients with cirrhosis, treatment planning must consider both the severity of liver ...
Busuttil, Ronald W +2 more
core +2 more sources
Technical Review of Magnetic Resonance Fingerprinting Applications in Cerebral Physiology
Magnetic Resonance in Medicine, EarlyView.ABSTRACT Magnetic resonance fingerprinting (MRF) enables quantitative MRI by allowing the simultaneous mapping of multiple tissue properties through innovative acquisition and computational methods. This review focuses on the application of MRF techniques to cerebral physiology, emphasizing advancements in vascular imaging and the integration of ...
Chieh‐Te Lin +2 more
wiley +1 more source
Defective Uterine Spiral Artery Remodeling and Placental Senescence in a Pregnant Rat Model of Polycystic Ovary Syndrome [PDF]
, 2023 Min Hu +10 more
openalex +1 more source
Uncovering the Genetic Landscape of Spinal Dysraphism: A Retrospective Analysis of 150 Fetal Cases
Prenatal Diagnosis, EarlyView.ABSTRACT Objective Spinal dysraphism (SD) results from incomplete neural tube closure and encompasses a heterogeneous group of congenital anomalies with genetic and environmental etiologies. Although genetic contributions are recognized, causative variants remain insufficiently defined, and the clinical implications of extended genetic testing on ...
I. Bedei +9 more
wiley +1 more source
B-Flow/Spatiotemporal Image Correlation M-Mode and Contrast-Enhanced/Microbubble Ultrasonography Quantification of Spiral Artery Distensibility and Placental Intervillous Perfusion in the First Trimester in a Primate Model of Impaired Spiral Artery Remodeling. [PDF]
Ultrasound Med Biol, 2023 Turan OM +5 more
europepmc +1 more source
EVALUATION OF UNK CELL CAPACITY TO INITIATE PREGNANCY-ASSOCIATED SPIRAL ARTERY REMODELLING
, 2010 Transient uterine Natural Killer (uNK) cells are the predominant leukocytes of early gestational human and murine uteri. Murine uNK cells promote changes in endometrial structure including initiation of perivascular smooth muscle reduction in spiral arteries. Less is known about human uNK cell functions due to sampling constraints.
Michael Joseph Bilinski
openalex +3 more sources
Environmental Toxicology, EarlyView.ABSTRACT Exposure to mono(2‐ethylhexyl) phthalate (MEHP) during pregnancy has been associated with adverse pregnancy and birth outcomes characterized by extravillous trophoblast (EVT) abnormal function. Previous reports have suggested that MEHP can activate the PI3K/AKT pathway in EVT cells, a pathway known to regulate inflammation and angiogenesis in ...
Luis Daniel Martínez‐Razo +5 more
wiley +1 more source