Results 181 to 190 of about 6,534 (210)

Spiral Artery Remodeling and Trophoblast Invasion in Preeclampsia and Fetal Growth Restriction [PDF]

Hypertension, 2013
Failure to transform uteroplacental spiral arteries is thought to underpin disorders of pregnancy, including preeclampsia and fetal growth restriction (FGR). In this study, spiral artery remodeling and extravillous-cytotrophoblast were examined in placental bed biopsies from normal pregnancy (n=25), preeclampsia (n=22), and severe FGR (n ...
Judith Bulmer, Fiona Lyall
exaly   +4 more sources

Some of the next articles are maybe not open access.

Related searches:

Deep trophoblast invasion and spiral artery remodelling in the placental bed of the chimpanzee

Placenta, 2011
Deep trophoblast invasion is usually considered to be a unique feature of human placentation as compared to other primates. Because of the occasional occurrence of preeclampsia in great apes, which in the human is associated with impaired deep invasion, this uniqueness may be questioned. The availability of two well-documented pregnant chimpanzee uteri
Pijnenborg, R, Vercruysse, L, Carter, Anthony Michael; id_orcid 0000-0002-8359-2085   +2 more
openaire   +2 more sources

Decidual spiral artery remodelling begins before cellular interaction with cytotrophoblasts

Placenta, 1998
Endometrial arteries undergo structural alterations during pregnancy to increase blood flow to the intervillous space. It is hypothesized that physiologic change in decidual arteries is similar to vascular remodelling seen in other organs. Histologic features of spiral arteries in secretory endometrial biopsies were compared blindly to decidual ...
C M, Craven, T, Morgan, K, Ward
openaire   +2 more sources

Ex vivo endothelin dependent contraction of the remodeled rat spiral artery

Placenta, 2014
Similarities of the rat to the human placenta make rat pregnancy models relevant to the study of human gestational diseases. Understanding of species differences is necessary to extrapolate from animal models to humans. We observed alpha-smooth muscle actin (αSMA) expression in rat endovascular trophoblasts (EVasT) and investigated the spatial and ...
I, Ariel, G, Skarzinski, T, Kossovsky, V, Belzer, D, Knigin, M, Khamaisi, Z, Abassi, M, Bursztyn   +7 more
openaire   +2 more sources

The role of the placenta in the initiation of spiral artery remodelling in an early pregnant chimpanzee uterus

Placenta, 2017
In this study we evaluated the full extent of placental bed changes (centre to periphery) in a pregnant chimpanzee uterus, kept at the Museum for Central Africa in Tervuren, Belgium. According to placental size the specimen was equivalent to an 8 weeks pregnant human uterus.Histological sections from central to peripheral tissue blocks of the placental
L. Vercruysse, A.M. Carter, R. Pijnenborg   +2 more
openaire   +3 more sources

Deep trophoblast invasion and spiral artery remodelling in the placental bed of the lowland gorilla

Placenta, 2011
In contrast to baboon or rhesus macaque, trophoblast invasion in the human placental bed occurs by the interstitial as well as the endovascular route and reaches as deep as the inner myometrium. We here describe two rare specimens of gorilla placenta.
Pijnenborg, R, Vercruysse, L, Carter, Anthony Michael; id_orcid 0000-0002-8359-2085   +2 more
openaire   +3 more sources

Spiral artery remodeling and maternal cardiovascular risk: the spiral artery remodeling (SPAR) study

2016
BACKGROUND:: Women with a history of placental bed disorders, including preeclampsia and intrauterine growth restriction have an increased long-term risk of cardiovascular disease (CVD). Further, similarities exist between atherosclerosis and abnormalities observed in placental bed spiral arteries in pregnancies affected by preeclampsia and ...
Veerbeek, Jan H W, Brouwers, Laura, Koster, Maria P H, Koenen, Steven V., van Vliet, Elvira O G, Nikkels, Peter G J, Franx, Arie, van Rijn, Bas B., Circulatory Health, MS Verloskunde, Metabole ziekten patientenzorg, Pathologie Pathologen staf, Cancer, Brain, DV&B-MT-Medisch   +14 more
openaire   +2 more sources

Trophoblast Invasion: Remodelling of Spiral Arteries and Beyond

2018
Despite massive scientific and clinical efforts, the etiology of preeclampsia remains a mystery. Quite a variety of different hypotheses has been developed and this is ongoing, but none of them has been able to explain the symptoms of the different preeclampsia subtypes satisfactorily.
openaire   +1 more source

Role of IDO1 in the spiral artery remodeling during pregnancy

During gestation, the trophoectoderm, the outer layer of the blastocyst, engages with the uterine wall to form the placenta, a temporary organ at the maternal-fetal vascular interface. To increase blood flow through the placenta, uterine spiral arteries transform into large, dilated, low-resistance vessels in which the endothelial layer has been ...
Dema Ghaban, Alison Carey
openaire   +1 more source

Dysregulated Mitochondrial Calcium Causes Spiral Artery Remodeling Failure in Preeclampsia

Hypertension
BACKGROUND: Calcium deficiency in women is strongly linked to an increased risk of developing preeclampsia. Mitochondrial calcium ([Ca 2+ ] m ) homeostasis is essential to regulate vascular smooth muscle cell (VSMC) function. However, the role of [Ca
Xiyuan Lu, Yifan Wang, Na Geng, Zhiguo Zou, Xueqing Feng, Yuehong Wang, Zhice Xu, Ning Zhang, Jun Pu   +8 more
openaire   +2 more sources