Results 41 to 50 of about 3,016,957 (322)

Desing, synthesis and anti-inflammatory activity of dirivatives 10-R-3-aryl-6,7-dihydro-2H-[1,2,4]triazino[2,3-c]quinazolin-2-ones of spiro-fused cyclic frameworks

Acta Chimica Slovenica, 2017
Present work is devoted to the purposeful search of novel promising anti-inflammatory agents among the insufficiently known 3'-R-10'-R1-spiro[hetaryl-3(4),6'-[1,2,4]triazino[2,3-c]quinazolin]-2'(7'H)-ones.
Oleksandra Kolomoets, Oleksii Voskoboynik, Oleksii Antypenko, Galyna Berest, Inna Nosulenko, Vitaliy Palchikov, Olexandr Karpenko, Sergiy Kovalenko   +7 more
doaj   +1 more source

Spiro heterocyclic compounds. VI. Synthesis of spiro(imidazolidine-4,1'-isoindoline) and related compounds.

Chemical and Pharmaceutical Bulletin, 1982
AbstractAus dem Homophthalsäureimid (I) erhält man mit Natriumnitrit das Oxim (II), das bei der Hydrierung ein Gemisch aus der Imino‐ Verbindung (III) und dem Dimeren (IV) liefert.
Mari Shigetsuna, Sachiyo Tahara, Hirotaka Otomasu   +2 more
openaire   +4 more sources

Organocatalytic Asymmetric Synthesis of Six‐Membered Carbocycle‐Based Spiro Compounds

, 2018
Well-developed asymmetric organocatalysis has been widely incorporated in various cascade/tandem sequences, providing simple access to structurally complex target molecules in a highly stereoselective fashion, including spirocyclic compounds.
Xie Xin, Wei Huang, Cheng Peng, Bo Han
semanticscholar   +1 more source

Synthesis of spiro quasi[1]catenanes and quasi[1]rotaxanes via a templated backfolding strategy

Nature Communications, 2017
Spiro compounds contain two or more rings linked together through one common atom. Here the authors provide a method to backfold both rings, producing spiro quasi[1]catenanes, via a strategy of temporarily linking the linear intermediates with covalent ...
Luuk Steemers, Martin J. Wanner, Martin Lutz, Henk Hiemstra, Jan H. van Maarseveen   +4 more
doaj   +1 more source

(±)-Peniorthoesters A and B, Two Pairs of Novel Spiro-Orthoester en-antiomers With an Unusual 1,4,6-Trioxaspi-ro[4.5]decane-7-One Unit From Penicillium minioluteum

Frontiers in Chemistry, 2018
(±)-Peniorthoesters A and B (±1 and ±2), two pairs of unprecedented spiro-orthoester enantiomers with a 1,4,6-trioxaspiro[4. 5]decane-7-one unit, were obtained from Penicillium minioluteum. Their structures were determined by spectroscopic methods, X-ray
Xiaorui Liu, Chunmei Chen, Yinyu Zheng, Mi Zhang, Qingyi Tong, Junjun Liu, Qun Zhou, Jianping Wang, Zengwei Luo, Hucheng Zhu, Yonghui Zhang   +10 more
doaj   +1 more source

Peniciadametizine A, a Dithiodiketopiperazine with a Unique Spiro[furan-2,7'-pyrazino[1,2-b][1,2]oxazine] Skeleton, and a Related Analogue, Peniciadametizine B, from the Marine Sponge-Derived Fungus Penicillium adametzioides

Marine Drugs, 2015
Peniciadametizine A (1); a new dithiodiketopiperazine derivative possessing a unique spiro[furan-2,7'-pyrazino[1,2-b][1,2]oxazine] skeleton, together with a highly oxygenated new analogue, peniciadametizine B (2); as well as two known compounds ...
Yang Liu, Attila Mándi, Xiao-Ming Li, Ling-Hong Meng, Tibor Kurtán, Bin-Gui Wang   +5 more
doaj   +1 more source

Facile, Regio- and Diastereoselective Synthesis of Spiro-Pyrrolidine and Pyrrolizine Derivatives and Evaluation of Their Antiproliferative Activities

Molecules, 2014
A number of novel spiro-pyrrolidines/pyrrolizines derivatives were synthesized through [3+2]-cycloaddition of azomethine ylides with 3,5-bis[(E)-arylmethylidene]tetrahydro-4(1H)-pyridinones 2a–n.
Abdulrahman I. Almansour, Raju Suresh Kumar, Farzana Beevi, Amir Nasrolahi Shirazi, Hasnah Osman, Rusli Ismail, Tan Soo Choon, Brian Sullivan, Kellen McCaffrey, Alaa Nahhas, Keykavous Parang, Mohamed Ashraf Ali   +11 more
doaj   +1 more source

Spiro-Compounds. Synthesis and Dehydrogenation of Spiro (5,5) undecanes

, 1972
Department of Chemistry, Kalyani University, Kalyani, West Bengal (Received 29 October 1971) Synthesis of 1-ethyl-3'-methyl-8,9 benzospiro-(5,5) undecane and 1-ethyl-3’-methyl-8,9- benzospiro (5,5) undecan-10-ol have been described. Catalytic dehydrogenation of both the spiro compounds by heating with Pd-C catalyst at 360° in a sealed tube gave 1-ethyl-
ASHUTOSH MITRA, SUNIL BARAN DAS
openaire   +2 more sources

Spiro Cyclohexadienones from the Reaction of Phenolic Enaminone Derivatives with Hypervalent Iodine Reagents

Molecules, 2000
Phenolic enamino compounds, prepared from 2-(4-hydroxyphenyl)-ethylamine and the corresponding β-keto carbonyl compounds, afford spiro cyclohexadienone derivatives on reaction with hypervalent iodine reagents.
Anastasios Varvoglis, Spyros Spyroudis, Ioannis Papoutsis, Anna Asmanidou   +3 more
doaj   +1 more source

ChemInform Abstract: SPIRO HETEROCYCLIC COMPOUNDS. III. SYNTHESIS OF SPIRO(OXINDOLE‐3,4′‐(4′H‐PYRAN)) COMPOUNDS

Chemischer Informationsdienst, 1980
AbstractDie Michaeladdition von CH‐aciden Verbindungen (II) bzw. (IV) an die Oxindole (I) führt in einer mehrstufigen Reaktion zu den Spiroverbindungen (III) bzw. (V).
Kimio Higashiyama, Hirotaka Otomasu
openaire   +4 more sources