Results 101 to 110 of about 50,141 (259)

Statement from the frontal fibrosing alopecia international expert alliance: SOFFIA 2024

open access: yesJournal of the European Academy of Dermatology and Venereology, EarlyView.
Optimal treatment for frontal fibrosing alopecia (FFA) remains contentious. An international expert panel agreed that highly/ultra‐potent topical steroids were the preferred first‐line topical therapy. Preferred systemic therapies were 5‐alpha reductase inhibitors, followed by hydroxychloroquine.
Nekma Meah   +64 more
wiley   +1 more source

Prescribing Patterns in Pediatric Hidradenitis Suppurativa

open access: yesPediatric Dermatology, EarlyView.
ABSTRACT Hidradenitis suppurativa (HS) is an inflammatory skin condition increasingly diagnosed in pediatric populations; however, data on treatment practices in this group remains limited. In this retrospective study of 163 patients diagnosed with HS ≤ 18 years of age, we found that treatment patterns varied significantly by disease severity.
Hannah Neimy   +3 more
wiley   +1 more source

Caenorhabditis elegans as an in vivo model system for human inherited primary arrhythmia syndromes

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Most genes involved in inherited primary arrhythmia syndromes (IPAS) are conserved in Caenorhabditis elegans, where genetic manipulation enables functional characterization of variants, identification of regulatory proteins, and in vivo drug testing.
Antoine Delinière   +6 more
wiley   +1 more source

A Case of Worsened Refractory Ascites due to Prednisolone Administration for Stricture Prevention after Endoscopic Submucosal Dissection for Extensive Early Esophageal Cancer: Case Report and Literature Review

open access: yesDEN Open, Volume 6, Issue 1, April 2026.
ABSTRACT Endoscopic submucosal dissection (ESD) is widely used for early esophageal cancer, even in patients with liver cirrhosis (LC). Corticosteroids, administered orally or by local injection, are often used to prevent post‐ESD esophageal stricture. However, their safety in patients with decompensated LC and refractory ascites remains unclear. A man
Yuki Tamura   +9 more
wiley   +1 more source

Rethinking Statin Dosage in Coronary Disease

open access: yesPharmacology Research &Perspectives, Volume 14, Issue 1, February 2026.
It is widely acknowledged that a sufficient statin dose is important in the management of symptomatic coronary disease, along with weight reduction and appropriate antithrombotic, blood pressure, and diabetes pharmacotherapy. Mid‐range statin doses have been shown to achieve the maximum improvements in total mortality and have the advantage of greater ...
Simon B. Dimmitt   +3 more
wiley   +1 more source

Emerging methods for subtype differentiation in primary aldosteronism

open access: yesJournal of Internal Medicine, Volume 299, Issue 2, Page 178-195, February 2026.
Abstract Primary aldosteronism (PA) is a common cause of hypertension. Compared to patients with essential hypertension, untreated PA is associated with a two‐ to fourfold greater risk of cardiovascular disease, renal failure, and death. PA is caused by increased secretion of aldosterone from one adrenal gland in 30% of the patients and both adrenal ...
Oskar Ragnarsson   +5 more
wiley   +1 more source

Retroperitoneal Dedifferentiated Liposarcoma With Penetrating Abscess Formation Secondary to Ileal Invasion: A Case Report

open access: yesClinical Case Reports, Volume 14, Issue 1, January 2026.
ABSTRACT Liposarcoma is a relatively common malignant soft tissue tumor in adults. Dedifferentiated liposarcoma (DLS) is a particularly invasive subtype characterized by high recurrence rates and a poor prognosis. We describe a case of a retroperitoneal liposarcoma with poor differentiation that presented with peritonitis accompanied by ileal ...
Kenichiro Yambe   +7 more
wiley   +1 more source

Multi‐Chamber Intracardiac Thrombi Complicated With Pulmonary and Lower Extremity Thrombosis in Male Patient: Case Report and Literature Reviews

open access: yesClinical Case Reports, Volume 14, Issue 1, January 2026.
ABSTRACT Multi‐chamber intracardiac thrombi are a rare and high‐risk complication in dilated cardiomyopathy, even during sinus rhythm. This case highlights the associated dangers of hemodynamic compromise and systemic embolization. Management requires vigilant anticoagulation and close monitoring to balance thromboembolic and bleeding risks.
Eba Fufa   +10 more
wiley   +1 more source

3.1 REDUCING ARTERIAL STIFFNESS INDEPENDENTLY OF BP: PROOF OF CONCEPT? CAVI, PWV AND CARDIAC DATA IN THE 6-MONTH VASERA TRIAL

open access: yesArtery Research, 2016
Purpose/ background/ objectives: People with or at risk of Type II diabetes (T2DM) are at increased risk of vascular disease and arterial stiffness (AS).
Charlotte Mills   +8 more
doaj   +1 more source

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