Results 141 to 150 of about 61,341 (287)

Mineralocorticoid receptor antagonism in acutely decompensated chronic heart failure [PDF]

open access: yes, 2013
Spironolactone was likely to provide faster congestion relief. -------------------------------------------------------------------------------- Abstract Background/objectives Mineralocorticoid receptor antagonist (MRA) use in acutely ...
Almeida, S.   +5 more
core   +3 more sources

European Journal of Heart Failure consensus statement. Heart failure pharmacotherapy for patients with heart failure with reduced ejection fraction and concomitant atrial fibrillation: Review of evidence and call to action

open access: yesEuropean Journal of Heart Failure, EarlyView.
Heart failure (HF) and atrial fibrillation (AF) are major global health challenges with rising prevalence and significant morbidity, mortality, and healthcare burden. Despite advances in HF management, AF remains a critical comorbidity that worsens outcomes and requires ad hoc treatment strategies, increasing the risk of non‐adherence and side effects.
Mark Luedde   +24 more
wiley   +1 more source

Evaluation of spironolactone plus hydrochlorothiazide in reducing proteinuria in type 2 diabetic nephropathy [PDF]

open access: yes, 2015
Introduction: Inhibitors of the renin-angiotensin aldosterone system (RAAS) are the basic drugs for treatment of diabetic nephropathy, as to some extent is spironolactone.
Behradmanesh, Mohammad Saeed   +3 more
core  

Urinary markers in heart failure – types, timing and thresholds. European Journal of Heart Failure expert consensus document

open access: yesEuropean Journal of Heart Failure, EarlyView.
Pathophysiologic mechanisms of heart failure (HF) (i.e. renin–angiotensin–aldosterone system [RAAS], congestion, and inflammation), together with patient‐related factors such as diabetes, hypertension, and chronic kidney disease (CKD), contribute to kidney function decline and glomerular or tubular injury.
Masatake Kobayashi   +14 more
wiley   +1 more source

Remission during pregnancy of severe Chronic Hypertension due to 11-ß Hydroxylase Deficiency [PDF]

open access: yes, 2004
When hypertension is a result of an underlying identifiable abnormality, the latter's early discovery can lead to a timely cure of the hypertension and the prevention of its complications.
Attard, Gerhardt, Cachia, Mario J.
core  

Unexpected Giant Right Coronary Artery Aneurysm Diagnosed by Computed Tomography Angiography in the Emergency Department

open access: yesJournal of Clinical Ultrasound, EarlyView.
3D Volume Rendering coronary CTA reconstruction showing a giant thrombosed aneurysm of the proximal right coronary artery ABSTRACT Giant coronary artery aneurysms (GCAA) are usually defined as diameter > 8 mm or > 400% of the adjacent normal segment; they are very rare (reported prevalence ≈0.02%).
Stefano Giusto Picchi   +8 more
wiley   +1 more source

GAMBARAN PERESEPAN SPIRONOLACTONE PADA PASIEN GAGAL JANTUNG DI RSUP DR KARIADI SEMARANG [PDF]

open access: yes, 2015
Background Heart failure is a clinical syndrome caused by abnormalities of cardiac structure or function. A condition when the heart as a pump can’t fulfill body’s blood demand to keep tissue’s metabolism well.
Anggriyani, Novi, Ksatria, Feby Tegar
core   +1 more source

Factors Associated With Male Breast Cancer Incidence Among Prostate Cancer Survivors: Real World Evidence From Veterans Affairs National Prostate Cancer Data Core

open access: yesThe Prostate, EarlyView.
ABSTRACT Background While male breast cancer incidence is rare, veteran status is found to be associated with increased risk, for incidence, a higher prevalence of male breast cancer patients was observed among male veteran prostate cancer survivors.
Erum Z. Whyne   +5 more
wiley   +1 more source

A Dose‐Aware Model for Revealing Dose‐Risk Relationship of Drug–Drug Interaction

open access: yesCPT: Pharmacometrics &Systems Pharmacology, EarlyView.
ABSTRACT Drug–drug interaction (DDI) is a common cause of adverse drug events (ADEs). Despite real‐world data‐based studies have developed knowledge on DDI, the precise relationships between doses of two‐drug combinations exposure and the risks of ADEs remain largely unknown.
Yi Shi   +8 more
wiley   +1 more source

Clinical Phenogroups in Heart Failure With Preserved Ejection Fraction: Detailed Phenotypes, Prognosis, and Response to Spironolactone.

open access: yesJACC. Heart failure, 2020
Jordana B. Cohen   +17 more
semanticscholar   +1 more source

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