Results 141 to 150 of about 46,150 (319)
Advancing antihypertensive drug development
Hypertension affects more than a billion individuals worldwide and remains a major cause of cardiovascular morbidity and mortality. Despite advances in therapies, optimal blood pressure control remains elusive for many patients because of treatment resistance, adverse effects, and adherence challenges.
Fay Pu+5 more
wiley +1 more source
Serum Estradiol Concentrations With Estradiol 0.06% Gel in Transgender and Gender‐Diverse Adults
ABSTRACT Objective Transgender and gender‐diverse individuals undergoing estradiol therapy for gender affirmation are typically treated with oral or transdermal estradiol, with transdermal estradiol recommended for those aged > 45 years. There are limited data evaluating estradiol gel in gender‐affirming hormone therapy regimens. We aimed to assess the
Raquel A. Maggacis+2 more
wiley +1 more source
A comparison of the potassium and magnesium‐sparing properties of amiloride and spironolactone in diuretic‐treated normal subjects. [PDF]
D. Murdoch+3 more
openalex +1 more source
Clinical Significance of Skeletal Fat‐to‐Muscle Ratio in Idiopathic Hyperaldosteronism
ABSTRACT Objective The objective of this study is to evaluate the correlation between the fat‐to‐muscle ratio (FMR) and insulin resistance (IR) with aldosterone production among patients with idiopathic hyperaldosteronism (IHA). Methods Patients with primary aldosteronism were screened from those with secondary hypertension and then subtyped via ...
Yuhe Jiang+6 more
wiley +1 more source
Renal sodium handling and neurohumoral systems in patients with cirrhosis in sitting posture [PDF]
Gerbes, Alexander L.+3 more
core +1 more source
The interplay between heart failure and chronic kidney disease
Abstract Chronic kidney disease (CKD) and heart failure (HF) are two globally prevalent, independent, long‐term conditions, which often coexist in an individual and display a bidirectional yet interconnected relationship. The presence of CKD often leads to the development of HF and vice versa, which propagates the worsening of each disease, reflecting ...
Anuradha Lala+2 more
wiley +1 more source
Inflammation in atherosclerotic cardiovascular disease: From diagnosis to treatment
Inflammation in atherosclerotic cardiovascular disease. Residual inflammatory risk (RIR), defined by high‐sensitive C‐reactive protein (hsCRP) concentration of ≥2 mg/L, represents a strong predictor of future atherosclerotic cardiovascular disease (ASCVD) events. Although increased hsCRP values ≥2 mg/L might be detected in every three out of five ASCVD
Natalie Arnold, Wolfgang Koenig
wiley +1 more source
Introduction: It is crucial to utilize combination therapy for immunoglobulin A nephropathy (IgAN) patients to reduce proteinuria and maintain stable kidney function.
Da Shang+4 more
doaj +1 more source