Results 41 to 50 of about 50,141 (259)

Outcomes of Spironolactone Withdrawal in Dilated Cardiomyopathy With Improved Ejection Fraction

Frontiers in Cardiovascular Medicine, 2021
Background: The feasibility of spironolactone withdrawal in dilated cardiomyopathy patients with improved ejection fraction remains unknown. This study sought to determine whether spironolactone can be withdrawn safely in this circumstance.Methods ...
Yanjia Chen, Yanjia Chen, Zeping Qiu, Zeping Qiu, Jie Jiang, Xiuxiu Su, Fanyi Huang, Fanyi Huang, Jing Tang, Wei Jin, Wei Jin   +10 more
doaj   +1 more source

Factors Associated With Male Breast Cancer Incidence Among Prostate Cancer Survivors: Real World Evidence From Veterans Affairs National Prostate Cancer Data Core. [PDF]

Prostate
ABSTRACT Background While male breast cancer incidence is rare, veteran status is found to be associated with increased risk, for incidence, a higher prevalence of male breast cancer patients was observed among male veteran prostate cancer survivors.
Whyne EZ, Choi SH, Unni N, Kanjwal S, Dowell JE, Jeon-Slaughter H.   +5 more
europepmc   +2 more sources

Amiloride reduces portal hypertension in rat liver cirrhosis [PDF]

, 2010
Objective This study aimed to investigate the effect of amiloride on portal hypertension. Amiloride is known to inhibit Na(+)/H(+) exchangers on activated hepatic stellate cells.
Beitinger, Frigga, Bystron, Markus, De Toni, Enrico N., Gerbes, Alexander L., Hartmann, Anna C., Hennenberg, Martin, Steib, Christian J.   +6 more
core   +1 more source

Hyperkalemia in women with acne exposed to oral spironolactone: A retrospective study from the RADAR (Research on Adverse Drug Events and Reports) program

International Journal of Women's Dermatology, 2019
Purpose: The necessity of serum potassium monitoring for healthy women who are prescribed spironolactone for acne has been debated. The aim of this study was to compare the incidence of hyperkalemia in women 18 to 45 years of age to that in women 46 to ...
Rebecca M. Thiede, Supriya Rastogi, Beatrice Nardone, Lauren M. Sadowsky, Stephanie M. Rangel, Dennis P. West, Bethanee J. Schlosser   +6 more
doaj   +1 more source

Efficacy and Safety of Spironolactone in the Treatment of Resistant Hypertension：a Meta-analysis [PDF]

Zhongguo quanke yixue, 2022
BackgroundAs a special type of hypertension, resistant hypertension has complex etiology, is difficult to treat, and more likely to lead to target organ damage.
ZHANG Ping, ZOU Jing, GAO Cunzhou, WU Aiping, LI Rongshan
doaj   +1 more source

Patiromer to Enable Spironolactone Use in the Treatment of Patients with Resistant Hypertension and Chronic Kidney Disease: Rationale and Design of the AMBER Study [PDF]

, 2018
BACKGROUND: While chronic kidney disease (CKD) is common in resistant hypertension (RHTN), prior studies -evaluating mineralocorticoid receptor antagonists excluded patients with reduced kidney function due to risk of hyperkalemia.
Agarwal, Rajiv, Arthur, Susan, Garza, Dahlia, Mayo, Martha R., Romero, Alain, Rossignol, Patrick, Warren, Suzette, White, William B., Williams, Bryan   +8 more
core   +2 more sources

A combined clinical and biomarker approach to predict diuretic response in acute heart failure [PDF]

, 2015
Background: Poor diuretic response in acute heart failure is related to poor clinical outcome. The underlying mechanisms and pathophysiology behind diuretic resistance are incompletely understood.
Bloomfield, Daniel M., Bruno, Noemi, Cleland, John G.F., Cotter, Gad, Damman, Kevin, Davison, Beth, Dittrich, Howard C., Givertz, Michael M., Hillege, Hans L., Metra, Marco, O’Connor, Christopher M., Ponikowski, Piotr, Teerlink, John R., ter Maaten, Jozine M., Valente, Mattia A.E., van Veldhuisen, Dirk J., Voors, Adriaan A.   +16 more
core   +4 more sources

Spironolactone lowers portal hypertension by inhibiting liver fibrosis, ROCK-2 activity and activating NO/PKG pathway in the bile-duct-ligated rat. [PDF]

PLoS ONE, 2012
OBJECTIVE: Aldosterone, one of the main peptides in renin angiotensin aldosterone system (RAAS), has been suggested to mediate liver fibrosis and portal hypertension.
Wei Luo, Ying Meng, Hong-Li Ji, Chun-Qiu Pan, Shan Huang, Chang-Hui Yu, Li-Ming Xiao, Kai Cui, Shu-Yuan Ni, Zhen-Shu Zhang, Xu Li   +10 more
doaj   +1 more source

The role of hypothalamus-pituitary-adrenal (HPA)-like axis in inflammatory pilosebaceous disorders [PDF]

, 2020
Skin is the largest peripheral endocrine organ and functions as a hormone target and endocrine gland. A cutaneous hypothalamus-pituitary-adrenal (HPA)-like axis enables the skin to respond to stress and regulates its steroidogenic activity.
Clark, Ashley K, Saric-Bosanac, Suzana, Shi, Vivian Y, Sivamani, Raja K   +3 more
core  

Medical treatment of ascites in cirrhosis [PDF]

, 1993
Medical treatment of cirrhotic ascites is essentially supportive, dictated by the patient's discomfort, impaired cardiovascular or respiratory function and potential for infection. Treatment of ‘simple’ ascites (moderate fluid accumulation, serum albumin
Alexander L. Gerbes, Bernardi, Bichet, Bosch, Broekhuysen, Caramelo, Conn, DiBona, Epstein, Faloon, Fogel, Fuller, Ganger, Gerbes, Gerbes, Gerbes, Gerbes, Gerbes, Gerbes, Gerbes, Gerbes, Gerbes, Ginès, Gregory, Guarner, Henriksen, Hoermann, Jüngst, Karnad, Keppler, Laffi, Lenz, Levy, Moore, Perez-Ayuso, Petrillo, Pockros, Ring-Larsen, Schrier, Schölmerich, Shear, Sherlock   +41 more
core   +1 more source